Zobrazeno 1 - 10
of 945
pro vyhledávání: '"tp63"'
Autor:
Yui Niiyama‐Uchibori, Shinsuke Mizutani, Taku Tsukamoto, Haruya Okamoto, Daisuke Ide, Akio Onishi, Daishi Kato, Takahiro Fujino, Yuji Shimira, Aya Miyagawa‐Hayashino, Eiichi Konishi, Kennosuke Karube, Yasuhito Nannya, Junya Kuroda
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 798-801 (2024)
Abstract In ALK‐negative anaplastic large cell lymphoma (ALCL), gene rearrangements of DUSP22 and TP63 are considered mutually exclusive. The former predicts a favorable prognosis, while the latter is generally unfavorable. We report the first case
Externí odkaz:
https://doaj.org/article/d6c191da8c874987bff4280cefb003d4
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies with a 5‐year survival rate of only 15% in patients with advanced diseases. Tumor protein 63 (TP63), a master transcription factor (TF) in ESCC, cooperates
Externí odkaz:
https://doaj.org/article/c4985d6919fa4701aba5b9e6da3c0873
Autor:
Alevtina Gall, Marita Bosticardo, Stacey Ma, Karin Chen, Kayla Amini, Francesca Pala, Ottavia M. Delmonte, Tara Wenger, Michael Bamshad, John Sleasman, Matthew Blessing, Nicolai S. C. van Oers, Luigi D. Notarangelo, M. Teresa de la Morena
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pathogenic variants in the transcription factor TP63 are associated with clinically overlapping syndromes including ectrodactyly-ectodermal dysplasia clefting (EEC) and ankyloblepharon-ectodermal defects-cleft lip/palate (AEC). T cell lymphopenia has
Externí odkaz:
https://doaj.org/article/f3b40d2853fc4c849e9c6fd59b40708d
Autor:
Traoré Lassina, Savadogo Mousso, Zouré Abdou Azaque, Kiendrebeogo Touwendpoulimdé Isabelle, Soudre Fabienne Marie B. T. B., Dabre Soayebo, Traore Aida Djé Djénéba, Adico Marc Donald Wilfried, Lare Tilate, Ouedraogo Teega-Wendé Clarisse, Ouedraogo Rogomenoma Alice, Ouattara Abdoul Karim, Yelemkoure Edwige T., Sawadogo Alexis Yobi, Zongo Nayi, Bambara Hierrhum Aboubacar, Nadembega Christelle W., Djigma Florencia W., Simpore Jacques
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 209-49 (2024)
Genetic alterations in the TP63 (GenBank: NC_000003.12, ID: 8626) and CCR5 (receptor 5 chemokine co-receptor) (GenBank: NC_000003.12, ID: 1234) genes may increase the risk of developing breast cancer. The aim of this study was to investigate the prob
Externí odkaz:
https://doaj.org/article/a2334ef0c738490ab25b03b42696f6d0
Autor:
Yali Fan, Shuya Chen, Chunfang Chu, Xiaodan Yin, Jing Jin, Lingyan Zhang, Huihui Yan, Zheng Cao, Ruixia Liu, Mingwei Xin, Lin Li, Chenghong Yin
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Background Premature ovarian insufficiency (POI) is a severe disorder leading to female infertility. Genetic mutations are important factors causing POI. TP63-truncating mutation has been reported to cause POI by increasing germ cell apoptos
Externí odkaz:
https://doaj.org/article/ff0b246776f94482b6921ed3a060baaa
Autor:
R. Sultanov, A. Mulyukina, O. Zubkova, A. Fedoseeva, A. Bogomazova, K. Klimina, A. Larin, T. Zatsepin, T. Prikazchikova, M. Lukina, M. Bogomiakova, E. Sharova, E. Generozov, M. Lagarkova, G. Arapidi
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background Prostate adenocarcinoma (PRAD) is the second leading cause of cancer-related deaths in men. High variability in DNA methylation and a high rate of large genomic rearrangements are often observed in PRAD. Results To investigate the
Externí odkaz:
https://doaj.org/article/de8467b7e9804ea7be2cf36b001cb329
Autor:
Yufen Chen, Zhen Wang, Xiaolu Qu, Bangmin Song, Yueting Tang, Bugao Li, Guoqing Cao, Guoqiang Yi
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
BackgroundPorcine skeletal muscle development is pivotal for improving meat production. TP63, a transcription factor, regulates vital cellular processes, yet its role in skeletal muscle proliferation is unclear.MethodsThe effects of TP63 on skeletal
Externí odkaz:
https://doaj.org/article/7e52151642c14c0da6afda43ebc8232f
Autor:
Boting Ning, Andrew M. Tilston-Lunel, Justice Simonetti, Julia Hicks-Berthet, Adeline Matschulat, Roxana Pfefferkorn, Avrum Spira, Matthew Edwards, Sarah Mazzilli, Marc E. Lenburg, Jennifer E. Beane, Xaralabos Varelas
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Bronchial premalignant lesions (PMLs) are composed primarily of cells resembling basal epithelial cells of the airways, which through poorly understood mechanisms have the potential to progress to lung squamous cell carcinoma (LUS
Externí odkaz:
https://doaj.org/article/8eeb49dcba4b46ed83d733498621d057
Autor:
Chih-Hung Lin, Po-Liang Cheng, Cheng-Yeh Chuang, Yu-Ting Kang, Li-Wen Lee, Tzu-Hung Hsiao, Chung-Ping Hsu
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1101 (2024)
Esophageal cancer ranks among the ten most common cancers worldwide. Despite the adoption of neoadjuvant concurrent chemoradiotherapy (nCCRT) followed by surgery as the standard treatment approach in recent years, the local recurrence rate remains hi
Externí odkaz:
https://doaj.org/article/b3d9ce590bce4feeb0d37bfe8c700434
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 264-265 (2024)
Externí odkaz:
https://doaj.org/article/84812179e5ed44ac9f90564542dcff63