Zobrazeno 1 - 10
of 1 245
pro vyhledávání: '"toxin–antitoxin system"'
Autor:
Hebin Liao, Xiaodan Yan, Chenyi Wang, Chun Huang, Wei Zhang, Leyi Xiao, Jun Jiang, Yongjia Bao, Tao Huang, Hanbo Zhang, Chunming Guo, Yufeng Zhang, Yingying Pu
Publikováno v:
eLife, Vol 13 (2024)
Biofilms are complex bacterial communities characterized by a high persister prevalence, which contributes to chronic and relapsing infections. Historically, persister formation in biofilms has been linked to constraints imposed by their dense struct
Externí odkaz:
https://doaj.org/article/c11cf25ae6ee40e3a190849636af158f
Autor:
Yongkui Chen, Ying-Xian Goh, Peifei Li, Jiahao Guan, Yanjie Chao, Hongping Qu, Hong-Yu Ou, Xiaoli Wang
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTHypervirulent Klebsiella pneumoniae isolates have been increasingly reported worldwide, especially hypervirulent drug-resistant variants owing to the acquisition of a mobilizable virulence plasmid by a carbapenem-resistant strain. This pLVPK-
Externí odkaz:
https://doaj.org/article/30c89dbc01304fab8b71c0b1952b6cc4
Autor:
Yawei Hou, Yifan Li, Ningning Tao, Xianglong Kong, Yameng Li, Yao Liu, Huaichen Li, Zhenguo Wang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundThe toxin-antitoxin (TA) system plays a vital role in the virulence and pathogenicity of Mycobacterium tuberculosis (M. tuberculosis). However, the regulatory mechanisms and the impact of gene mutations on M. tuberculosis transmission remai
Externí odkaz:
https://doaj.org/article/6c98e4e22bdc4486a9f6cf4db12e05e5
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The toxin-antitoxin (TA) system plays a key role in bacteria escaping antibiotic stress with persistence, however, the mechanisms by which persistence is controlled remain poorly understood. Weissella cibaria, a novel probiotic, can enters a persiste
Externí odkaz:
https://doaj.org/article/d3cf18f25a574c1dab3f00f01154ac8d
Autor:
Wei Wei, Lindsey Burbank
Publikováno v:
PhytoFrontiers, Vol 3, Iss 2, Pp 337-346 (2023)
Xylella fastidiosa has multiple chromosomally encoded type II toxin-antitoxin (TA) systems, several of which have unknown functions in the bacterial lifecycle. In many bacterial species, type II TA systems are associated with bacterial stress surviva
Externí odkaz:
https://doaj.org/article/7b8f7c46c7d34ce5845f91cd4e337764
Autor:
Fisentzos Floras, Chantell Mawere, Manvir Singh, Victoria Wootton, Luke Hamstead, Gareth McVicker, Jack C. Leo
Publikováno v:
Biology, Vol 13, Iss 9, p 652 (2024)
The bacterium Yersinia ruckeri causes enteric redmouth disease in salmonids and hence has substantial economic implications for the farmed fish industry. The Norwegian Y. ruckeri outbreak isolate NVH_3758 carries a relatively uncharacterized plasmid,
Externí odkaz:
https://doaj.org/article/a27f98a0441a4dd4857c3671072dbcad
Autor:
Talita Duarte Pagani, Paloma Rezende Corrêa, Cristiane Lima, Leonardo Henrique Ferreira Gomes, Marcos Gustavo Araujo Schwarz, Teca Calcagno Galvão, Wim Maurits Degrave, Napoleão Fonseca Valadares, Leila Mendonça-Lima
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 8, Pp 6538-6549 (2023)
Mycobacterium bovis BCG is the only vaccine against tuberculosis. The variable forms of cultivation throughout the years, before seed-lots were developed, allowed in vitro evolution of the original strain, generating a family of vaccines with differe
Externí odkaz:
https://doaj.org/article/ecaf66e95a7447b28c50f39d0a5f6e6b
Publikováno v:
Toxins, Vol 16, Iss 5, p 208 (2024)
Recent discoveries establish DNA and RNA as bona fide substrates for ADP-ribosylation. NADAR (“NAD- and ADP-ribose”-associated) enzymes reverse guanine ADP-ribosylation and serve as antitoxins in the DarT-NADAR operon. Although NADARs are widespr
Externí odkaz:
https://doaj.org/article/8173d3fb39f74abd942bd7c18384f47a
Publikováno v:
Antibiotics, Vol 13, Iss 5, p 398 (2024)
Klebsiella pneumoniae causes severe human diseases, but its resistance to current antibiotics is increasing. Therefore, new antibiotics to eradicate K. pneumoniae are urgently needed. Bacterial toxin–antitoxin (TA) systems are strongly correlated w
Externí odkaz:
https://doaj.org/article/567742051adf4b4d84a3f15c5296460b
Autor:
Jordan D. Lin, Peter J. Stogios, Kento T. Abe, Avril Wang, John MacPherson, Tatiana Skarina, Anne-Claude Gingras, Alexei Savchenko, Alexander W. Ensminger
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Toxin-antitoxin (TA) systems are abundant genetic modules in bacterial chromosomes and on mobile elements. They are often patchily distributed, as a consequence of horizontal exchange, and the breadth of their functionality in bacterial phys
Externí odkaz:
https://doaj.org/article/b2ffacc24f704038bfbfdf5f027fa204