Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes, via activation of mTORC1 in the medial prefrontal cortex in lipopolysaccharide-induced depression model mice.

Autor: Deyama, Satoshi¹ (AUTHOR) deyama@p.kanazawa-u.ac.jp, Sugie, Rinako¹ (AUTHOR), Tabata, Masaki¹ (AUTHOR), Kaneda, Katsuyuki¹ (AUTHOR)

Publikováno v: Nutritional Neuroscience. Aug2024, Vol. 27 Issue 8, p795-808. 14p.

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Tomatidine Extraction from Various Solvents and Cancer Inhibition Mechanism Through In Silico Analysis.

Autor: Lisdiana, Lisdiana¹ lisdiana@mail.unnes.ac.id, Iswari, Retno Sri¹, Christijanti, Wulan¹, Harjono Harjono², Sasi, Fitri Arum³, Dafip, Muchamad^1,4

Publikováno v: Trends in Sciences. Oct2023, Vol. 20 Issue 10, p1-12. 12p.

Tomatidine attenuates lipopolysaccharide-induced nerve cell injury via transcription factor EB.

Autor: ZHANG Weigang¹, WANG Lei¹, MAO Jiayue¹, ZHANG Jie¹, CHEN Yuqing¹, DONG Minghui¹, LI Shu¹, WANG Lin¹

Publikováno v: Chinese Journal of Pathophysiology. Dec2023, Vol. 39 Issue 12, p2123-2132. 10p.

Exploring the Effects of Tomatidine ((3β, 5α, 22β, and 25β)-Spirosolan-3-ol) on Voltage-gated Na+ currents: Insights Into Its Ionic Mechanisms of Action on Current Magnitude, Gating, and Frequency Dependence.

Autor: Lin TL; Department of Paediatrics, An Nan Hospital, China Medical University, Tainan, Taiwan., So EC; Department of Anaesthesia, An Nan Hospital, China Medical University, Tainan, Taiwan.; Department of Cell Biology and Anatomy, National Cheng Kung University Medical College, Tainan, Taiwan.; Department of Anaesthesiology, University of Hong Kong, Hong Kong., Wu SN; Department of Physiology, National Cheng Kung University Medical College, Tainan, Taiwan.; Institute of Basic Medical Sciences, National Cheng Kung University Medical College, Tainan, Taiwan.; Department of Medical Education and Research, An Nan Hospital, China Medical University, Tainan, Taiwan.

Publikováno v: Journal of physiological investigation [J Physiol Investig] 2024 Nov 01; Vol. 67 (6), pp. 298-311. Date of Electronic Publication: 2024 Dec 06.