Zobrazeno 1 - 10
of 853
pro vyhledávání: '"toll-like receptor 4 (tlr4)"'
Autor:
Sandeep Yadav, Mohd. Aslam, Ayushi Prajapat, Iona Massey, Bhaskara Nand, Durgesh Kumar, Kamlesh Kumari, Garima Pandey, Chandrabhan Verma, Prashant Singh, Akram AlFantazi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract The widespread use of pesticides poses significant threats to both environmental and human health, primarily due to their potential toxic effects. The study investigated the cardiovascular toxicity of selected pesticides, focusing on their i
Externí odkaz:
https://doaj.org/article/734af09154d9488fa837cd9cd7a90152
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 16, Pp 340-347 (2024)
Objective: To investigate the effect and mechanism of Hippophae rhamnoides flavone (HRF) on polycystic ovarian syndrome (PCOS) in rats, and to provide new ideas for the prevention and treatment of PCOS. Methods: A PCOS rat model was duplicated by giv
Externí odkaz:
https://doaj.org/article/5f6eaec194a9434398d23e58bee4909a
Publikováno v:
Renal Failure, Vol 46, Iss 1 (2024)
Objective This study was designed to observe the effect of toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) pathway activity on sepsis-associated acute kidney injury (SA-AKI), thereby providing new considerations for the prevention and tre
Externí odkaz:
https://doaj.org/article/535110157df24377afd50559a4bcfc3e
Publikováno v:
Toxicology Reports, Vol 11, Iss , Pp 355-367 (2023)
Confronting the profound public health concern of alcohol-induced liver damage calls for inventive therapeutic measures. The social, economic, and clinical ramifications are extensive and demand a comprehensive understanding. This thorough examinatio
Externí odkaz:
https://doaj.org/article/b240be7957674d3e8a08ad01ec1fdf06
Autor:
Raquel Dos Santos Martins, Jan B. F. Hulscher, Albert Timmer, Elisabeth M. W. Kooi, Klaas Poelstra
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
IntroductionNecrotizing enterocolitis (NEC) is a life-threatening inflammatory disease. Its onset might be triggered by Toll-Like Receptor 4 (TLR4) activation via bacterial lipopolysaccharide (LPS). We hypothesize that a deficiency of intestinal alka
Externí odkaz:
https://doaj.org/article/b071803383f8418d8e7846566a81e56c
Publikováno v:
Guoji Yanke Zazhi, Vol 23, Iss 10, Pp 1709-1713 (2023)
AIM: To investigate the expression and clinical significance of Toll-like receptor 4(TLR4)and vascular endothelial growth factor A(VEGFA)in the serum of patients with diabetic retinopathy(DR).METHODS: A total of 183 patients with type 2 diabetes mell
Externí odkaz:
https://doaj.org/article/a12c3d070b374cfa917db98191d38269
Autor:
Eun-Young Kim, Ji-Eun Kim, Soo-Hyun Chung, Ji-Eun Park, Dohee Yoon, Hyo-Jin Min, Yoolim Sung, Soo Been Lee, Seong Who Kim, Eun-Ju Chang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Toll-like receptor 4 (TLR4) conducts a highly regulated inflammatory process by limiting the extent of inflammation to avoid toxicity and tissue damage, even in bone tissues. Thus, it is plausible that strategies for the maintenan
Externí odkaz:
https://doaj.org/article/c1aa2215a83f48b587ca69ce98c6a8d9
Autor:
Chao Zhang, Yanlang Yang
Publikováno v:
Biomolecules & Biomedicine (2023)
The clinical manifestation of hyperuricaemia, known as hyperuricaemia nephropathy, is relatively common. Its pathophysiology is largely based on chronic inflammation in circulatory and renal tissues. Toll-like receptor 4 (TLR4), a subclass of innate
Externí odkaz:
https://doaj.org/article/77a589417c3d4f8c9a4cbaa5dbf62bae
Publikováno v:
Liver Research, Vol 7, Iss 1, Pp 1-8 (2023)
Alcohol-related liver disease (ALD) became an important health issue worldwide. Following chronic alcohol consumption, the development of ALD might be caused by metabolic and immunologic factors, such as reactive oxygen species (ROS) and pro-inflamma
Externí odkaz:
https://doaj.org/article/8ccf24c67fb840558ba8129febfaaf86
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Contrast-induced acute kidney injury (CI-AKI) is the third most common cause of hospital-acquired renal failure. However, there is no effective treatment of CI-AKI, and its mechanism is unknown. Interestingly, atorvastatin has bee
Externí odkaz:
https://doaj.org/article/9f635f9ca42a4f689e6e7f8712abe29d