Zobrazeno 1 - 10
of 2 058
pro vyhledávání: '"tolerogenic"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Gene editing of living cells has become a crucial tool in medical research, enabling scientists to address fundamental biological questions and develop novel strategies for disease treatment. This technology has particularly revolutionized a
Externí odkaz:
https://doaj.org/article/72a5f87a160448cb8626c2ded775f7af
Autor:
Fatemeh Asgari, Mahdi Khodadoust, Abdolrahim Nikzamir, Somayeh Jahani‐Sherafat, Mostafa Rezaei Tavirani, Mohammad Rostami‐Nejad
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background In mammals, amino acid metabolism has evolved to control immune responses. Tryptophan (Trp) is the rarest essential amino acid found in food and its metabolism has evolved to be a primary regulatory node in the control of immune r
Externí odkaz:
https://doaj.org/article/693ad1d67905428780b30f47c2cf31a0
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 20, Iss 1, Pp 1-9 (2024)
Abstract H. pylori is a gram-negative bacterium that is usually acquired in childhood and can persistently colonize the gastric mucosa of humans, affecting approximately half of the world’s population. In recent years, the prevalence of H. pylori i
Externí odkaz:
https://doaj.org/article/a39da42efdbc476cb8c7938d03a9b9ea
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute kidney injury (AKI) is characterized by a rapid decline in renal function and is associated with a high morbidity and mortality rate. At present, the underlying mechanisms of AKI remain incompletely understood. Immune disorder is a prominent fe
Externí odkaz:
https://doaj.org/article/cb3a60ae73af4809aa7b1bca439c22fc
Autor:
Anikó E. Malik, Drew Slauenwhite, Sarah M. McAlpine, John G. Hanly, Jean S. Marshall, Thomas B. Issekutz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveAntigen-presenting dendritic cells (DCs) and monocytes play an essential role in rheumatoid arthritis (RA) pathogenesis, however, their tolerogenic potential remains unclear. Herein, the tolerogenic profiles of DCs are characterized in treat
Externí odkaz:
https://doaj.org/article/ada887f28e424002807018d3e254353f
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Radiation-induced lung injury is a common complication associated with radiotherapy. It is characterized by early-stage radiation pneumonia and subsequent radiation pulmonary fibrosis. However, there is currently a lack of effective therapeutic strat
Externí odkaz:
https://doaj.org/article/c4d375a6a61b414081055191a4d3d75d
Autor:
Gaona Shi, Yu Zhou, Wenshuai Liu, Chengjuan Chen, Yazi Wei, Xinlong Yan, Lei Wu, Weiwei Wang, Lan Sun, Tiantai Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 6, Pp 2778-2794 (2023)
Tolerogenic dendritic cells (tolDCs) facilitate the suppression of autoimmune responses by differentiating regulatory T cells (Treg). The dysfunction of immunotolerance results in the development of autoimmune diseases, such as rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/29fdddd46e6440ee884d46b379a326f3
Autor:
Mohammed Ghiboub, Matthew Bell, Dovile Sinkeviciute, Rab K. Prinjha, Menno P. J. de Winther, Nicola R. Harker, David F. Tough, Wouter J. de Jonge
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 5, Pp 4228-4245 (2023)
SP140 is an epigenetic reader protein expressed predominantly in immune cells. GWAS studies have shown an association between SP140 single nucleotide polymorphisms (SNPs) and diverse autoimmune and inflammatory diseases, suggesting a possible pathoge
Externí odkaz:
https://doaj.org/article/3c050099aea741a3bd355412024aa66a
Autor:
Samuel J Gavzy, Allison Kensiski, Zachariah L Lee, Emmanuel F Mongodin, Bing Ma, Jonathan S Bromberg
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTBifidobacterium is a widely distributed commensal bacterial genus that displays beneficial pro-homeostatic and anti-inflammatory immunomodulatory properties. Depletion or absence of Bifidobacterium in humans and model organisms is associated
Externí odkaz:
https://doaj.org/article/80e4ff0cd0d747bdbf46b4bf723576c9
Autor:
Chenglin Kang, Xiaomei Li, Peng Liu, Yue Liu, Yuan Niu, Xianhai Zeng, Hailiang Zhao, Jiangqi Liu, Shuqi Qiu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Dendritic cells (DCs), central participants in the allergic immune response, can capture and present allergens leading to allergic inflammation in the immunopathogenesis of allergic rhinitis (AR). In addition to initiating antigen-specific immune res
Externí odkaz:
https://doaj.org/article/fb0680b8845d4c66b98be21bf172d204