Lung Cancer Screening: Low-Dose Thoracic Computed Tomography Performed in a High-Risk Portuguese Population

Autor: Sara Moura Cabral, Inês Abreu, Daniela Madama, Amélia Estevão, Eugénio Cordeiro, João Pimentel, Nuno Miranda, António Jorge Ferreira, Carlos Robalo Cordeiro

Publikováno v: Acta Médica Portuguesa, Vol 36, Iss 9 (2023)

Introduction: The Urgeiriça mines were once the main uranium producer in Portugal. The aim of this study was to estimate the benefit of low-dose chest computed tomography (LDCT) for lung cancer screening in former miners that were considered as bein

Externí odkaz: https://doaj.org/article/12ccf86c43f84de79eeb79e158744e20

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Dysregulated mitochondrial metabolism upon cigarette smoke exposure in various human bronchial epithelial cell models

Autor: Christy B. M. Tulen, Ying Wang, Daan Beentjes, Phyllis J. J. Jessen, Dennis K. Ninaber, Niki L. Reynaert, Frederik-Jan van Schooten, Antoon Opperhuizen, Pieter S. Hiemstra, Alexander H. V. Remels

Publikováno v: Disease Models & Mechanisms, 15(3):049247. Company of Biologists Ltd
Disease Models and Mechanisms, 15(3). COMPANY BIOLOGISTS LTD

Exposure to cigarette smoke (CS) is the primary risk factor for developing chronic obstructive pulmonary disease. The impact of CS exposure on the molecular mechanisms involved in mitochondrial quality control in airway epithelial cells is incomplete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ec9d0bd70b6fc6d76a428662e39da1
https://doi.org/10.1242/dmm.049247

Electronic Cigarette Use and the Diagnosis of Nonmelanoma Skin Cancer Among United States Adults

Autor: Shelby Breit, Hayrettin Okut, Katelyn Dugan, Elizabeth Ablah

Publikováno v: Cureus

Introduction Electronic cigarette (e-cigarette) use has many potential effects, including damage to the skin. Limited research has assessed e-cigarette use with the incidence of nonmelanoma skin cancer. The current study was conducted to determine if

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264d5e5293d250bd8fb14d4b2dc28a18
http://europepmc.org/articles/PMC8608672

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

Autor: Liu, M, Jiang, Y, Wedow, R, Li, Y, Brazel, DM, Chen, F, Datta, G, Davila-Velderrain, J, McGuire, D, Tian, C, Zhan, X, Team, 23Andme Research, Psychiatry, Hunt All-In, Choquet, H, Docherty, AR, Faul, JD, Foerster, JR, Fritsche, LG, Gabrielsen, ME, Gordon, SD, Haessler, J, Hottenga, J-J, Huang, H, Jang, S-K, Jansen, PR, Ling, Y, Mägi, R, Matoba, N, McMahon, G, Mulas, A, Orrù, V, Palviainen, T, Pandit, A, Reginsson, GW, Skogholt, AH, Smith, JA, Taylor, AE, Turman, C, Willemsen, G, Young, H, Young, KA, Zajac, GJM, Zhao, W, Zhou, W, Bjornsdottir, G, Boardman, JD, Boehnke, M, Boomsma, DI, Chen, C, Cucca, F, Davies, GE, Eaton, CB, Ehringer, MA, Esko, T, Fiorillo, E, Gillespie, NA, Gudbjartsson, DF, Haller, T, Harris, KM, Heath, AC, Hewitt, JK, Hickie, IB, Hokanson, JE, Hopfer, CJ, Hunter, DJ, Iacono, WG, Johnson, EO, Kamatani, Y, Kardia, SLR, Keller, MC, Kellis, M, Kooperberg, C, Kraft, P, Krauter, KS, Laakso, M, Lind, PA, Loukola, A, Lutz, SM, Madden, PAF, Martin, NG, McGue, M, McQueen, MB, Medland, SE, Metspalu, A, Mohlke, KL, Nielsen, JB, Okada, Y, Peters, U, Polderman, TJC, Posthuma, D, Reiner, AP, Rice, JP, Rimm, E, Rose, RJ, Runarsdottir, V, Stallings, MC, Stančáková, A, Stefansson, H, Thai, KK, Tindle, HA, Tyrfingsson, T, Wall, TL, Weir, DR, Weisner, C, Whitfield, JB, Winsvold, BS, Yin, J, Zuccolo, L, Bierut, LJ, Hveem, K, Lee, JJ, Munafò, MR, Saccone, NL, Willer, CJ, Cornelis, MC, David, SP, Hinds, DA, Jorgenson, E, Kaprio, J, Stitzel, JA, Stefansson, K, Thorgeirsson, TE, Abecasis, G, Liu, DJ, Vrieze, S

Publikováno v: Liu, M, Jiang, Y, Wedow, R, Li, Y, Brazel, D M, Chen, F, Datta, G, Davila-Velderrain, J, McGuire, D, Tian, C, Zhan, X, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, Hinds, D A, Hromatka, B S, Huber, K E, Kleinman, A, Litterman, N K, McIntyre, M H, Mountain, J L, Northover, C A M, Sathirapongsasuti, J F, Sazonova, O V, Shelton, J F, Shringarpure, S, Tian, C, Tung, J Y, Vacic, V, Wilson, C H, Pitts, S J, Mitchell, A, Skogholt, A H, Winsvold, B S, Sivertsen, B R, Stordal, E, Morken, G, Kallestad, H V, Heuch, I, Zwart, J-A, Fjukstad, K K, Pedersen, L M, Gabrielsen, M E, Jansen, P R, Posthuma, D, 23andMe Research team, Jorgenson, E, Stitzel, J A, Liu, D J & Vrieze, S 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
Nature Genetics
the 23 and Me Research Team 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
Nature Genetics, 51(2), 237-244. Nature Publishing Group
Liu, M, Hottenga, J J, Jansen, P R, Willemsen, G, Boomsma, D I, Davies, G E, Polderman, T J C, Posthuma, D, Vrieze, S, 23Andme Research Team & HUNT All-In Psychiatry 2019, ' Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use ', Nature Genetics, vol. 51, no. 2, pp. 237-244 . https://doi.org/10.1038/s41588-018-0307-5
PMC
Nature genetics
Nature genetics, 51(2), 237-244. Nature Publishing Group

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex diseases and disorders1. They are heritable2,3 and etiologically related4,5 behaviors that have been resistant to gene discovery efforts6,7,8,9,10,11. In sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f01e166190b1f57e8157a42854d232
https://research.vumc.nl/en/publications/d6127763-905e-44ae-88b1-ab80a1e7e269