Zobrazeno 1 - 10
of 8 267
pro vyhledávání: '"tnfα"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11336-11348 (2024)
Inflammation is a tightly regulated process involving immune receptor recognition, immune cell migration, inflammatory mediator secretion, and pathogen elimination, all essential for combating infection and restoring damaged tissue. However, excessiv
Externí odkaz:
https://doaj.org/article/c9352e8111104cfaa3dcf06ccaf5adc4
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Sepsis is a pathological and biochemical disorder induced by numerous infections, leading to critical illness and a high mortality rate worldwide. Vincamine is an indole alkaloid compound obtained from the leaves of Vinca minor. The present
Externí odkaz:
https://doaj.org/article/634fbfa617ad49f8995c06113242466f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Inflammatory bowel disease is defined by inflammation and immune dysregulation. This study investigated the effects of Gα13 liver-specific knockout (LKO) on proximal and distal colons of dextran sodium sulfate (DSS)-induced mice in conjunct
Externí odkaz:
https://doaj.org/article/b66bf5bb51fc4e62aa5698a86ea0960e
Autor:
Marouf Alhalabi, Soumar Mueen Alziadan
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-7 (2024)
Abstract Background The role of cytomegalovirus infection as an opportunistic pathogen in exacerbating ulcerative colitis and its response to treatment remain a topic of ongoing debate. Clinicians encounter numerous challenges, including the criteria
Externí odkaz:
https://doaj.org/article/9b903caa9e3c430c83adcd448e5a1221
Autor:
Irina D. Bulgakova, V. V. Zverev, E. O. Kravtsova, G. N. Usatova, D. A. Shoichet, E. A. Zadvornykh, A. A. Shumkina
Publikováno v:
Инфекция и иммунитет, Vol 14, Iss 3, Pp 500-504 (2024)
Introduction. Today, prevalence of neurodegenerative diseases increases. In recent years, more studies have revealed a new knowledge about the role of microglia in the development of these diseases. Animal experiments showed that peripheral inflammat
Externí odkaz:
https://doaj.org/article/18a189aeef894167809a095a06623b04
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 765-770 (2024)
The development of subclinical atherosclerosis in patients with rheumatoid arthritis (RA) is associated with chronic inflammation, one of the key mechanisms of which may be abnormal activation of macrophages.Objective: To assess the characteristics o
Externí odkaz:
https://doaj.org/article/4b6cf093c00949d4b9399e3adbcc28aa
Autor:
C. I. Philippi, J. Hagens, K. M. Heuer, H. C. Schmidt, P. Schuppert, L. Pagerols Raluy, M. Trochimiuk, Z. Li, M. J. Bunders, K. Reinshagen, C. Tomuschat
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study explores the application of the RIP3-caspase3-assay in heterogeneous spheroid cultures to analyze cell death pathways, emphasizing the nuanced roles of apoptosis and necroptosis. By employing directly conjugated monoclonal antibod
Externí odkaz:
https://doaj.org/article/87996718065d4aaa9f3b411fe6dbe7d0
Autor:
Enrique Hernández-Jiménez, Erika P. Plata-Menchaca, Damaris Berbel, Guillem López de Egea, Macarena Dastis-Arias, Laura García-Tejada, Fabrizio Sbraga, Pierre Malchair, Nadia García Muñoz, Alejandra Larrad Blasco, Eva Molina Ramírez, Xose Pérez Fernández, Joan Sabater Riera, Arnau Ulsamer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBacteremia is a life-threatening condition that can progress to sepsis and septic shock, leading to significant mortality in the emergency department (ED). The standard diagnostic method, blood culture, is time-consuming and prone to fals
Externí odkaz:
https://doaj.org/article/8374191210b34e6cae49bd7ff3fd318b
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116733- (2024)
It has been well acknowledged that maternal exposure to fine particulate matters (PM2.5) might lead to poor pregnancy outcomes including the intrauterine growth restriction (IUGR) by interfering with the placental development. Our previous studies ha
Externí odkaz:
https://doaj.org/article/a879ad79b0864b22876d489374d43b50
Autor:
M. P. Kostinov, V. V. Gainitdinova, S. V. Kazharova, A. E. Vlasenko, V. B. Polishchuk, D. U. Allaberdina
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 577-590 (2024)
A decrease of nonspecific body resistance, an imbalance of local and systemic immunity and a free-radical oxidation abnormality substantially contribute to the pathogenesis of community-acquired pneumonia (CAP).Purpose: To study the efficiency of inc
Externí odkaz:
https://doaj.org/article/fb80af456f53477f9f60c486360eb66d