Zobrazeno 1 - 10
of 7 583
pro vyhledávání: '"tnbc"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cancer stem cells (CSCs) have the potential to self-renew and induce cancer, which may contribute to a poor prognosis by enabling metastasis, recurrence, and therapy resistance. Hence, this study was performed to identify the association bet
Externí odkaz:
https://doaj.org/article/8824695dcd1b4090affa6514bc9533fb
Autor:
Chrispus Ngule, Ruyi Shi, Xingcong Ren, Hongyan Jia, Felix Oyelami, Dong Li, Younhee Park, Jinhwan Kim, Hami Hemati, Yi Zhang, Xiaofang Xiong, Andrew Shinkle, Nathan L. Vanderford, Sara Bachert, Binhua P. Zhou, Jianlong Wang, Jianxun Song, Xia Liu, Jin-Ming Yang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Triple negative breast cancer (TNBC) is a particularly lethal breast cancer (BC) subtype driven by cancer stem cells (CSCs) and an immunosuppressive microenvironment. Our study reveals that nucleus accumbens associated protein 1 (NAC1), a me
Externí odkaz:
https://doaj.org/article/f74140f6f5a14ff3a6bfa413df989010
Autor:
Carolina Carlosama, Cindy Arévalo, María Camila Jimenez, Paola Lasso, Claudia Urueña, Susana Fiorentino, Alfonso Barreto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Tumor metabolism is a crucial aspect of cancer development, and mitochondria plays a significant role in the aggressiveness and metastasis of tumors. As a result, mitochondria have become a promising therapeutic target in cancer treatment, l
Externí odkaz:
https://doaj.org/article/8cff2678565a44d9a698f467022f5443
Autor:
Soheila Montazersaheb, Aziz Eftekhari, Amir Shafaroodi, Soodeh Tavakoli, Sara Jafari, Ayşe Baran, Mehmet Fırat Baran, Sevda Jafari, Elham Ahmadian
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Radiation therapy (RT) is a modality for TNBC management. Radiosensitizers can mitigate the adverse effects of RT. Applying green-synthesized silver n
Externí odkaz:
https://doaj.org/article/51089754c8d34974ad89b929a7939fa0
Autor:
Xiaorong Hou, Zhaofang Bai, Yuanyuan Chen, Wei Shi, Huijie Yang, Ruisheng Li, Xiaoyan Zhan, Youping Liu, Xu Zhao, Xiaohe Xiao
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Squama Manis is a valuable traditional Chinese medicine with a long history of medicinal use in the treatment of breast-related diseases. However, owing to the excessive exploitation and utilization of the resources, Squama Manis
Externí odkaz:
https://doaj.org/article/d44439efc9634ef1bbd8ed34823afca3
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Human trophoblastic cell surface antigen 2 (Trop2) is a glycoprotein, a cellular marker of trophoblastic and stem cells, and a calcium signaling transducer involved in several signaling pathways, leading to the proliferation, invasion, and m
Externí odkaz:
https://doaj.org/article/7214982032d74db3801c36504f675c87
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract To investigate the effects of higher cellular stanniocalcin 2 (STC2) on suppressing the migration and invasion but promoting the apoptosis of triple-negative breast cancer (TNBC). STC2 in TNBC and the para-carcinoma tissues were analyzed by
Externí odkaz:
https://doaj.org/article/df1df57340bf48418af3ce6ce4a0444c
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Triple negative breast cancer (TNBC) is a type of breast cancer that is negative for oestrogen receptor, progesterone receptor and human epidermal growth factor receptor 2, is highly malignant and aggressive, lacks of correspondin
Externí odkaz:
https://doaj.org/article/99501706471e4104ad5a18473d4cdcf1
Autor:
Claudia Cifuentes, Clara L. Oeste, Isabel Fernández-Pisonero, Alejandro M. Hortal, Carmen García-Macías, Jeanne Hochart, Regina Rubira, Lydia Horndler, Carlos Horndler, Xosé R. Bustelo, Balbino Alarcón
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-28 (2024)
Abstract Background Breast cancer (BC) is the most common cancer in women, with triple negative BC (TNBC) accounting for 20% of cases. While early detection and targeted therapies have improved overall life expectancy, TNBC remains resistant to curre
Externí odkaz:
https://doaj.org/article/50bafe4d36984ae5843b8ab7cb2b0b97
Autor:
Shivangi Agarwal, Monalisa Parija, Sanoj Naik, Pratima Kumari, Sandip K. Mishra, Amit K. Adhya, Sushil K. Kashaw, Anshuman Dixit
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Breast invasive carcinoma (BRCA) is the most malignant and leading cause of death in women. Global efforts are ongoing for improvement in early detection, prevention, and treatment. In this milieu, a comprehensive analysis of RNA-sequencing
Externí odkaz:
https://doaj.org/article/0459bb96a5244d0ea1121b11843a71ca