Zebrafish-based discovery of antiseizure compounds from the north sea: Isoquinoline alkaloids TMC-120A and TMC-120B

Autor: Silas Anselm Rasmussen, Sara Kildgaard, Monika Ślęzak, Camila V. Esguerra, Thomas Ostenfeld Larsen, Daniëlle Copmans, Peter de Witte, Michèle Partoens, Nina Dirkx, Alexander D. Crawford

Publikováno v: Copmans, D, Kildgaard, S, Rasmussen, S A, Ślezak, M, Dirkx, N, Partoens, M, Esguerra, C V, Crawford, A D, Larsen, T O & De Witte, P A M 2019, ' Zebrafish-based discovery of antiseizure compounds from the north sea: Isoquinoline alkaloids TMC-120A and TMC-120B ', Marine Drugs, vol. 17, no. 11, 607 . https://doi.org/10.3390/md17110607
Marine Drugs
Volume 17
Issue 11
Marine Drugs, Vol 17, Iss 11, p 607 (2019)

There is a high need for the development of new and improved antiseizure drugs (ASDs) to treat epilepsy. Despite the potential of marine natural products (MNPs), the EU marine biodiscovery consortium PharmaSea has made the only effort to date to perf

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https://orbit.dtu.dk/en/publications/1cba1001-99b4-4b69-92ff-cfda39e4aa59