Zobrazeno 1 - 10
of 12 885
pro vyhledávání: '"tlr2"'
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 711-716 (2024)
TLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens. Polymorphisms in genes involved
Externí odkaz:
https://doaj.org/article/72e52993f1694815a430cd012bf50fac
Autor:
Daping Xie, Congwei Han, Chonghao Chen, Zhencheng Liao, Senio Campos de Souza, Yiming Niu, João F. Mano, Lei Dong, Chunming Wang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 315-330 (2024)
Cancer vaccination holds great promise for cancer treatment, but its effectiveness is hindered by suboptimal activation of CD8+ cytotoxic T lymphocytes, which are potent effectors to mediate anti-tumor immune responses. A possible solution is to swit
Externí odkaz:
https://doaj.org/article/63cce374d08d4b5183ab56a352bb148e
Autor:
Anthea Miller, Giorgia Pia Lombardo, Giuseppina Rizzo, Magdalena Kotanska, Giuseppinella Melita, Socrate Pallio, Alba Migliorato, Giuseppina Cutroneo, Simona Pergolizzi
Publikováno v:
Gastroenterology Insights, Vol 15, Iss 3, Pp 541-554 (2024)
Inflammatory bowel diseases (IBDs) represent multifactorial chronic inflammatory conditions of the gastrointestinal tract. The main IBDs are Crohn’s disease (CD) and ulcerative colitis (UC). CD may cause perforation, stricture or transmural inflamm
Externí odkaz:
https://doaj.org/article/24816025f6e64b87a2245d8cdc5539a6
Autor:
Junyong Wang, Yuan Tang, Xuelian Zhao, Zetao Ding, Marhaba Ahmat, Dayong Si, Rijun Zhang, Xubiao Wei
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Thymopentin (TP5) plays an important role in host immunomodulation, yet its bioavailability is significantly limited by its short half-life. YW12D is a peptide with strong stability but relatively weak immunoactivity. Tuning the physicochemical prope
Externí odkaz:
https://doaj.org/article/7e092654f81f4df091a1f030407d1290
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionStreptococcus uberis is a member of the pyogenic cluster of Streptococcus commonly associated with intramammary infection and mastitis in dairy cattle. It is a poorly controlled globally endemic pathogen responsible for a significant caus
Externí odkaz:
https://doaj.org/article/6d47982fcb2342cf8811e16d1ec853d8
Autor:
Han Wang, Qi Xu, Heng Heng, Wenxing Zhao, Hongyuhang Ni, Kaichao Chen, Bill Kwan Wai Chan, Yang Tang, Miaomiao Xie, Mingxiu Peng, Edward Wai Chi Chan, Guan Yang, Sheng Chen
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105340- (2024)
Summary: Background: The continuous emergence of multidrug-resistant (MDR) Acinetobacter baumannii (Ab) strains poses further challenges in its control and clinical management. It is necessary to decipher the mechanisms underlying the high mortality
Externí odkaz:
https://doaj.org/article/877794228a95425d93ea26b6abe71772
Publikováno v:
Venereology, Vol 3, Iss 1, Pp 26-34 (2024)
The Arg753Gln polymorphism in Toll-like receptor 2 has been associated with an increased risk of bacterial infections as well as with protection from the late stages of Lyme disease and the acquisition of syphilis. In this study, we determined the pr
Externí odkaz:
https://doaj.org/article/8e0c9e2f8ed54562b0a8618afab75e91
Autor:
Davoud Ghazanfari, Maria Cecilia Courreges, Lydia E. Belinski, Michael J. Hogrell, Jacob Lloyd, Stephen C. Bergmeier, Kelly D. McCall, Douglas J. Goetz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract During a SARS-CoV-2 infection, macrophages recognize viral components resulting in cytokine production. While this response fuels virus elimination, overexpression of cytokines can lead to severe COVID-19. Previous studies suggest that the s
Externí odkaz:
https://doaj.org/article/56233cae8bb2417da30fac712d7f764f
Publikováno v:
陆军军医大学学报, Vol 46, Iss 8, Pp 829-836 (2024)
Objective To investigate the protective effect of Toll-like receptor (TLR) 2 /TLR9 agonists, Pam2CSK4 (Pam) and CpG ODN (CpG) on mice infected with Acinetobacter baumannii (Ab) in the lungs. Methods Female C57 mice (6~8 weeks old) were randomly divid
Externí odkaz:
https://doaj.org/article/45b11a81db0b416f9f1c3d1b7b9c7996
Autor:
Theresa Neuper, Tobias Frauenlob, Hieu-Hoa Dang, Peter W. Krenn, Gernot Posselt, Christof Regl, Nikolaus Fortelny, Veronika Schäpertöns, Michael S. Unger, Gunda Üblagger, Daniel Neureiter, Iris Mühlbacher, Michael Weitzendorfer, Franz Singhartinger, Klaus Emmanuel, Christian G. Huber, Silja Wessler, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Sophisticated immune evasion strategies enable Helicobacter pylori (H. pylori) to colonize the gastric mucosa of approximately half of the world’s population. Persistent infection and the resulting chronic inflammation are a major cause of gastric
Externí odkaz:
https://doaj.org/article/71409594e0d44f3793c2a852288917da