Successful heart transplant in a child with congenital core myopathy and delayed‐onset restrictive cardiomyopathy due to recessive mutations in the titin (TTN) gene.

Autor: Wacker, Julie^1,2 (AUTHOR) julie.wacker@hcuge.ch, Di Bernardo, Stefano^2,3 (AUTHOR), Lobrinus, Johannes Alexander⁴ (AUTHOR), Jungbluth, Heinz^5,6 (AUTHOR), Gautel, Mathias⁶ (AUTHOR), Beghetti, Maurice^1,2 (AUTHOR), Fluss, Joel⁷ (AUTHOR)

Publikováno v: Pediatric Transplantation. Sep2023, Vol. 27 Issue 6, p1-4. 4p.

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Titin (TTN): from molecule to modifications, mechanics, and medical significance.

Autor: Loescher CM; Department of Cardiology I, Coronary, Peripheral Vascular Disease and Heart Failure, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149 Münster, Germany., Hobbach AJ; Department of Cardiology I, Coronary, Peripheral Vascular Disease and Heart Failure, University Hospital Münster, Münster, Germany., Linke WA; Department of Cardiology I, Coronary, Peripheral Vascular Disease and Heart Failure, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149 Münster, Germany.

Publikováno v: Cardiovascular research [Cardiovasc Res] 2022 Nov 10; Vol. 118 (14), pp. 2903-2918.

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Titin (TTN): from molecule to modifications, mechanics, and medical significance

Autor: Wolfgang A. Linke, Anastasia J. Hobbach, Christine M Loescher

Publikováno v: Cardiovascular Research. 118:2903-2918

The giant sarcomere protein titin is a major determinant of cardiomyocyte stiffness and contributor to cardiac strain sensing. Titin-based forces are highly regulated in health and disease, which aids in the regulation of myocardial function, includi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13af594b578a223877976475148679ee
https://doi.org/10.1093/cvr/cvab328