Zobrazeno 1 - 10
of 487
pro vyhledávání: '"tissue protection"'
Autor:
Brooke L. Farrugia, James Melrose
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14101 (2023)
This review examines the roles of HS–proteoglycans (HS–PGs) in general, and, in particular, perlecan and syndecan as representative examples and their interactive ligands, which regulate physiological processes and cellular behavior in health and
Externí odkaz:
https://doaj.org/article/823a346bd21e4e4084f6e4ee35cbf483
Autor:
Riem Gawish, Barbara Maier, Georg Obermayer, Martin L Watzenboeck, Anna-Dorothea Gorki, Federica Quattrone, Asma Farhat, Karin Lakovits, Anastasiya Hladik, Ana Korosec, Arman Alimohammadi, Ildiko Mesteri, Felicitas Oberndorfer, Fiona Oakley, John Brain, Louis Boon, Irene Lang, Christoph J Binder, Sylvia Knapp
Publikováno v:
eLife, Vol 11 (2022)
Sepsis is a life-threatening condition characterized by uncontrolled systemic inflammation and coagulation, leading to multiorgan failure. Therapeutic options to prevent sepsis-associated immunopathology remain scarce. Here, we established a mouse mo
Externí odkaz:
https://doaj.org/article/488b92e3c6ae4a14a465997f8ae7c7c0
Autor:
Yedi Herdiana
Publikováno v:
Polymers, Vol 15, Iss 16, p 3485 (2023)
Gastroesophageal Reflux Disease (GERD) is a chronic ailment that results from the backward flow of stomach acid into the esophagus, causing heartburn and acid regurgitation. This review explores nanotechnology as a novel treatment approach for GERD.
Externí odkaz:
https://doaj.org/article/5d6ff84732ce4f6385064c82ab380be4
Autor:
Margaret M. Smith, James Melrose
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 437 (2023)
Pentosan polysulfate (PPS), a small semi-synthetic highly sulfated heparan sulfate (HS)-like molecule, shares many of the interactive properties of HS. The aim of this review was to outline the potential of PPS as an interventional therapeutic protec
Externí odkaz:
https://doaj.org/article/52f356245f6345b2b24a9d0b3b007418
Publikováno v:
Advanced Science, Vol 9, Iss 13, Pp n/a-n/a (2022)
Abstract Gaseous molecules have been increasingly explored for therapeutic development. Here, following an analytical background introduction, a systematic review of medical gas research is presented, focusing on tissue protections, mechanisms, data
Externí odkaz:
https://doaj.org/article/fe0e2a8449f3488e815d4d530504f76e
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100183- (2022)
The development of long lasting therapeutic agents is critically important for efficient treatment of chronic diseases. We herein report a rational strategy to develop a therapeutic thermogel featured with prolonged anti-inflammatory and corneal-prot
Externí odkaz:
https://doaj.org/article/8a180c58bd6245a2bfe0498b1d0096d6
Autor:
Anna L. Höving, Kazuko E. Schmidt, Barbara Kaltschmidt, Christian Kaltschmidt, Cornelius Knabbe
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9626 (2022)
Tissue regeneration substantially relies on the functionality of tissue-resident endogenous adult stem cell populations. However, during aging, a progressive decline in organ function and regenerative capacities impedes endogenous repair processes. E
Externí odkaz:
https://doaj.org/article/4337255411c64a519f232a9569fc1548
Akademický článek
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Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Annexin-A1 (ANXA1) was first discovered in the early 1980's as a protein, which mediates (some of the) anti-inflammatory effects of glucocorticoids. Subsequently, the role of ANXA1 in inflammation has been extensively studied. The biology of ANXA1 is
Externí odkaz:
https://doaj.org/article/0aa8338713444ddf92b98e665f1e5c69
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 9262 (2020)
The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs is a major goal in repair medicine. Stem cells are classified by their potential to differentiate into functional cells. Compared with other
Externí odkaz:
https://doaj.org/article/1f39209e3c6540cea7cedf9e7e1560b0