Zobrazeno 1 - 10
of 438
pro vyhledávání: '"tissue microenvironment"'
Publikováno v:
Bioactive Materials, Vol 35, Iss , Pp 461-476 (2024)
Obesity triggers inflammatory responses in the microenvironment of white adipose tissue, resulting in chronic systemic inflammation and the subsequent development of non-communicable diseases, including type 2 diabetes, coronary heart disease, and br
Externí odkaz:
https://doaj.org/article/c544f16ebb29432b926493482143f276
Autor:
Noyuri Zama, Satoshi Toda
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-7 (2024)
Abstract Cancer cell therapy, particularly chimeric antigen receptor (CAR) T-cell therapy for blood cancers, has emerged as a powerful new modality for cancer treatment. Therapeutic cells differ significantly from conventional drugs, such as small mo
Externí odkaz:
https://doaj.org/article/507b9594d31c4c9ba3ff622f0c27a2a2
Autor:
Laura Ingeborg Davidsen, Carolina E. Hagberg, Victor Goitea, Stine Meinild Lundby, Steen Larsen, Morten Frendø Ebbesen, Natasha Stanic, Hande Topel, Jan-Wilhelm Kornfeld
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Adipose tissues, particularly beige and brown adipose tissue, play crucial roles in energy metabolism. Brown adipose tissues’ thermogenic capacity and the appearance of beige cells within white adipose tissue have spurred interest in their metaboli
Externí odkaz:
https://doaj.org/article/06226211492f46eeb6a14f769791f6c1
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHypopharyngeal squamous cell carcinoma (HSCC) is one of the malignant tumors with the worst prognosis in head and neck cancers. The transformation from normal tissue through low-grade and high-grade intraepithelial neoplasia to cancerous
Externí odkaz:
https://doaj.org/article/283672fd7eb24e36b26daddd3d3955a9
Autor:
Jagabandhu Bag, Sabyasachi Banerjee, Arnab De, Sreejan Manna, Subhasis Banerjee, S. K. Ashok Kumar, Sourav De
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Background The second leading cause of mortality in the world, behind cardiovascular disorders, is cancer. The currently employed treatment options including radiotherapy, chemotherapy are reported with many adverse reactions. These limitati
Externí odkaz:
https://doaj.org/article/2f6eb429ec5a485191e45228fbf25bf4
Autor:
Cheng Chang, Xin Tang, Axel H. Schönthal, Mei Chen, David T. Woodley, Yanzhuang Wang, Chengyu Liang, Wei Li
Publikováno v:
Cells, Vol 13, Iss 15, p 1280 (2024)
Cell secretion repairs tissue damage and restores homeostasis throughout adult life. The extracellular heat shock protein-90alpha (eHsp90α) has been reported as an exosome cargo and a potential driver of wound healing. However, neither the mechanism
Externí odkaz:
https://doaj.org/article/9429bddcdb69401fb9f862dd0a194671
Autor:
Zhi-heng Luo, Jian-xiong Ma, Wei Zhang, Ai-xian Tian, Shu-wei Gong, Yan Li, Yu-xiao Lai, Xin-long Ma
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract The pathogenesis of osteoporosis involves multiple factors, among which alterations in the bone microenvironment play a crucial role in disrupting normal bone metabolic balance. Transient receptor potential vanilloid 5 (TRPV5), a member of t
Externí odkaz:
https://doaj.org/article/2187c4e34dc7408ebb32d7f162bc4ee1
Autor:
Dmitrii Atiakshin, Nina Kulchenko, Andrey Kostin, Michael Ignatyuk, Andrey Protasov, Ilya Klabukov, Denis Baranovskii, Mikhail Faniev, Elina Korovyakova, Irina Chekmareva, Igor Buchwalow, Markus Tiemann
Publikováno v:
Cells, Vol 13, Iss 10, p 833 (2024)
Infertility is an important personal and society disease, of which the male factor represents half of all causes. One of the aspects less studied in male infertility is the immunological testicular microenvironment. Mast cells (MCs), having high pote
Externí odkaz:
https://doaj.org/article/7a196573b5a643ee96f54cab3366a51f
Autor:
Serena Mancarella, Isabella Gigante, Grazia Serino, Elena Pizzuto, Francesco Dituri, Maria F. Valentini, Jingxiao Wang, Xin Chen, Raffaele Armentano, Diego F. Calvisi, Gianluigi Giannelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background Intrahepatic cholangiocarcinoma (iCCA) is a highly malignant tumor characterized by an intensive desmoplastic reaction due to the exaggerated presence of the extracellular (ECM) matrix components. Liver fibroblasts close to the tu
Externí odkaz:
https://doaj.org/article/04d9818126634bcbb9a920a39c75e01a
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
We have established a pseudotemporal ordering for the transcriptional signatures of distinct microregions within reactive lymphoid tissues, namely germinal center dark zones (DZ), germinal center light zones (LZ), and peri-follicular areas (Peri). By
Externí odkaz:
https://doaj.org/article/e042b52e459442c6b80bfa9002208b4d