Zobrazeno 1 - 10
of 17 553
pro vyhledávání: '"tissue microarray a"'
Autor:
Seyma Büyücek, Nina Schraps, Anne Menz, Florian Lutz, Viktoria Chirico, Florian Viehweger, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube-Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Morton Freytag
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-17 (2024)
Abstract Background Claudin-3 (CLDN3) participates in the formation of the tight-junctions (TJs) that regulate intercellular permeability. Altered CLDN3 expression has been linked to tumor progression in multiple tumor types. Despite its widespread e
Externí odkaz:
https://doaj.org/article/29aab683632e4490aaaf89e2dde1d4cb
Autor:
Kira Furlano, Henning Plage, Sebastian Hofbauer, Sarah Weinberger, Bernhard Ralla, Annika Fendler, Florian Roßner, Simon Schallenberg, Sefer Elezkurtaj, Martina Kluth, Maximilian Lennartz, Niclas C. Blessin, Andreas H. Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Joachim Weischenfeldt, Tobias Klatte, Thorsten Schlomm, David Horst, Henrik Zecha
Publikováno v:
BJUI Compass, Vol 5, Iss 11, Pp 1081-1089 (2024)
Abstract Objective There is a shortage of established prognostic biomarkers in bladder cancer. One candidate is tumour protein 63 (p63), a transcription factor of the p53 gene family that is expressed in the normal urothelium. Recently proposed RNA e
Externí odkaz:
https://doaj.org/article/858134d5041e486092630ed50c6fad55
Autor:
Henrike Barbara Zech, Clara von Bargen, Agnes Oetting, Nikolaus Möckelmann, Christina Möller-Koop, Melanie Witt, Nina Struve, Cordula Petersen, Christian Betz, Kai Rothkamm, Adrian Münscher, Till Sebastian Clauditz, Thorsten Rieckmann
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) negative for Human Papillomavirus (HPV) has remained a difficult to treat entity, whereas tumors positive for HPV are characterized by radiosensitivity and favorable patient outcome. O
Externí odkaz:
https://doaj.org/article/c1e43d1aa9b54a65af428ae6df20aafc
Autor:
Alexandre deNonneville, Elsa Kalbacher, Francesco Cannone, Arnaud Guille, José Adelaïde, Pascal Finetti, Maria Cappiello, Eric Lambaudie, Giuseppe Ettore, Emmanuelle Charafe, Emilie Mamessier, Magali Provansal, François Bertucci, Renaud Sabatier
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2586-2600 (2024)
Endometrioid ovarian cancers (EOvC) are usually managed as serous tumors. In this study, we conducted a comprehensive molecular investigation to uncover the distinct biological characteristics of EOvC. This retrospective multicenter study involved pa
Externí odkaz:
https://doaj.org/article/7e6216ea4f234271b8862b530fe72449
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Blacks/African American (BAA) patients diagnosed with head and neck squamous cell carcinoma (HNSCC) have worse survival outcomes than White patients. However, the mechanisms underlying racial disparities in HNSCC have not been tho
Externí odkaz:
https://doaj.org/article/2cd138a31c8d40ac99820dee8f89fef9
Autor:
Renan Gomes do Nascimento, Mércia Patrícia Ferreira da Conceição, Daniel Rodrigues de Bastos, Cynthia Aparecida Bueno de Toledo Osorio, Rossana Verónica Mendoza López, Eduardo Moraes Reis, Otto Luiz Dutra Cerqueira
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The search for prognostic markers in breast cancer has bumped into a typical feature of these tumors, intra and intertumoral heterogeneity. Changes in the expression profile, localization of these proteins or shedding to the surrounding stro
Externí odkaz:
https://doaj.org/article/6328f6277bc949a4b097a3f377ad88bf
Autor:
Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch, Till Krech, Patrick Lebok, Stefan Steurer, Eike Burandt, Sarah Minner, Andreas H. Marx, Ronald Simon, Waldemar Wilczak, Guido Sauter, Anne Menz, Frank Jacobsen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK7 overexpression was
Externí odkaz:
https://doaj.org/article/5ac61efaf1d649688eb409482a34a7c5
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 38, Iss 1 (2024)
We designed this study to identify potential diagnostic and prognostic markers for lung adenocarcinoma (LUAD). Four gene expression profiles were downloaded from GEO and merged into a training cohort, and those genes that were differentially expresse
Externí odkaz:
https://doaj.org/article/dd9efc54f8bd4b9483d3ee12e6070c21
Publikováno v:
ESMO Gastrointestinal Oncology, Vol 6, Iss , Pp 100105- (2024)
Background: There are limited treatment options for patients with advanced or metastatic gastrointestinal stromal tumours (GISTs) that lack mutations targetable by tyrosine kinase inhibitors (TKIs) or that have developed resistance to TKIs. Gastrin-r
Externí odkaz:
https://doaj.org/article/79bcba9d0c914c6fac7fa299b9a6c93f
Autor:
Lore De Cock, Flavia Paternostro, Ulla Vanleeuw, Karo Wyns, Annouschka Laenen, Che-Jui Lee, Raf Sciot, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102057- (2024)
Background: Synovial sarcoma (SynSa) is one of the most common translocation-related soft tissue sarcomas. Patients with metastatic SynSa have limited treatment options and a very poor prognosis. Several novel experimental therapies are currently bei
Externí odkaz:
https://doaj.org/article/1849db8fb1904ffe95310ec132df2b55