Zobrazeno 1 - 10
of 2 491
pro vyhledávání: '"tissue inflammation"'
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice
Autor:
Subin Moon, Yejin Park, Sooyeon Jang, Saeha Kim, Dan-Gyeong Song, Dae-Chul Shin, Chan Hee Lee
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background IL-2 regulates T cell differentiation: low-dose IL-2 induces immunoregulatory Treg differentiation, while high-dose IL-2 acts as a potent activator of cytotoxic T cells and NK cells. Therefore, high-dose IL-2 has been studied for
Externí odkaz:
https://doaj.org/article/6cb8a07e15ed40088848993a384e3abd
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-15 (2024)
Abstract Background Obesity is a global epidemic, and the low-grade chronic inflammation of adipose tissue in obese individuals can lead to insulin resistance and type 2 diabetes. Adipose tissue macrophages (ATMs) are the main source of pro-inflammat
Externí odkaz:
https://doaj.org/article/3ad9844f50dc4563bdf5a910d6d77bfa
Autor:
Antonio Cardamone, Anna Rita Coppoletta, Roberta Macrì, Saverio Nucera, Stefano Ruga, Federica Scarano, Rocco Mollace, Annachiara Mollace, Samantha Maurotti, Edoardo Micotti, Cristina Carresi, Vincenzo Musolino, Micaela Gliozzi, Vincenzo Mollace
Publikováno v:
Pharmacological Research, Vol 209, Iss , Pp 107417- (2024)
Non-alcoholic fatty liver disease (NAFLD), redefined as Metabolic Associated Fatty Liver Disease (MAFLD), is characterized by an extensive multi-organ involvement. MAFLD-induced systemic inflammatory status and peripheral metabolic alteration lead to
Externí odkaz:
https://doaj.org/article/dcf51dc87a7f4431baf3edcc3578743e
Autor:
Chirivi, Miguel 1, Abou-Rjeileh, Ursula 1, Gandy, Jeff 1, Parales-Giron, Jair 2, Panda, Vishal 3, 4, Terrian, Leah 3, 5, Bhattacharya, Sudin 3, 5, 6, 7, Lock, Adam L. 2, *, Contreras, G. Andres 1, *
Publikováno v:
In Journal of Dairy Science January 2025 108(1):1078-1091
Autor:
Huiyuan Zhai, Dongxu Wang, Yong Wang, Hongwei Gu, Juan Jv, Liangliang Yuan, Chao Wang, Leiyao Chen
Publikováno v:
Endocrine Connections, Vol 13, Iss 5, Pp 1-11 (2024)
Chronic inflammation induced by obesity plays a crucial role in the pathogenesis of insulin resistance. The infiltration of macrophages into adipose tissues contributes to adipose tissue inflammation and insulin resistance. Kaempferol, a flavonoid pr
Externí odkaz:
https://doaj.org/article/ebcca27d944e4ebbb33291e4eb5801d0
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Macrophage filopodia, which are dynamic nanotube-like protrusions, have mainly been studied in the context of pathogen clearance. The mechanisms by which they facilitate intercellular communication and mediate tissue inflammation remain poor
Externí odkaz:
https://doaj.org/article/067dcf397d2844ad97935a9e6758898f
Autor:
Kunal Sarkar, Sarbashri Bank, Arindam Chatterjee, Koushik Dutta, Anwesha Das, Santanu Chakraborty, Nirvika Paul, Jit Sarkar, Sriparna De, Sudakshina Ghosh, Krishnendu Acharyya, Dipankar Chattopadhyay, Madhusudan Das
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-25 (2023)
Abstract Type 2 diabetes mellitus (T2DM) predominantly considered a metabolic disease is now being considered an inflammatory disease as well due to the involvement of meta-inflammation. Obesity-induced adipose tissue inflammation (ATI) is one of the
Externí odkaz:
https://doaj.org/article/d20852e46891430aad1b05d3a61833c0
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundChronic and acute inflammation of the mucosa-associated lymphoid tissue have been positively linked to the development of psychiatric disorders in observational studies. However, it remains unclear whether this association is causal. In the
Externí odkaz:
https://doaj.org/article/49e1d7ea6e874754b5aa0e388abb4831
Autor:
Jan Ackermann, Lilli Arndt, Janine Fröba, Andreas Lindhorst, Markus Glaß, Michaela Kirstein, Constance Hobusch, F. Thomas Wunderlich, Julia Braune, Martin Gericke
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionObesity is associated with chronic low-grade inflammation of adipose tissue (AT) and an increase of AT macrophages (ATMs) that is linked to the onset of type 2 diabetes. We have recently shown that neutralization of interleukin (IL)-6 in
Externí odkaz:
https://doaj.org/article/92c010c02ff34f8d808756182478a481