Zobrazeno 1 - 10
of 316
pro vyhledávání: '"thyroid receptor"'
Autor:
Trinity Quan, Jessica Cockburn, Sukhbinder Dhesy-Thind, Anita Bane, Hon Leong, Christopher Geleff, Catherine Devion, Noor Ajel, Katarzyna J. Jerzak
Publikováno v:
Current Oncology, Vol 31, Iss 5, Pp 2364-2375 (2024)
Background: Breast cancer (BC) is frequently diagnosed among Canadian women. While targeted therapies are available for most BC patients; treatment resistance is common and novel therapeutic targets are of interest. Thyroid hormones (TH) bound to thy
Externí odkaz:
https://doaj.org/article/667202c7178345e89c8dd0d5a7baeddf
Autor:
Edelyn Christina, Hendra Budiawan, Hapsari Indrawati, Erwin Soeriadi, Trias Nugrahadi, A Hussein Kartamihardja
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 11, Iss 2, Pp 185-190 (2023)
Graves’ disease (GD) is the commonest cause of hyperthyroidism, accounted for 70-80% in iodine sufficient countries and up to 50% in iodine deficient countries. Combination of genetic predisposition and environmental factors influences the developm
Externí odkaz:
https://doaj.org/article/56eff70e91c84018ac5ef018cb569a23
Autor:
J. Porter Hunt, Tyler J. Free, Jackelyn Galiardi, Kevin M. Watt, David W. Wood, Bradley C. Bundy
Publikováno v:
Life, Vol 13, Iss 10, p 1972 (2023)
Thyroid receptor signaling controls major physiological processes and disrupted signaling can cause severe disorders that negatively impact human life. Consequently, methods to detect thyroid receptor ligands are of great toxicologic and pharmacologi
Externí odkaz:
https://doaj.org/article/3f7bf1f0c97f409fb006ab91c4f5e407
Publikováno v:
Zhongguo aizheng zazhi, Vol 31, Iss 3, Pp 161-169 (2021)
Background and purpose: Thyroid hormone and its receptors are closely related to breast cancer. Thyroid receptor-interacting protein 6 (TRIP6) may promote the occurrence and development of breast cancer by interacting with thyroid receptor. This stud
Externí odkaz:
https://doaj.org/article/5385ab348a8c49719c2a10af2aba9c1a
Autor:
Ryo Omagari, Mayuko Yagishita, Fujio Shiraishi, Ryo Kamata, Masanori Terasaki, Takuya Kubo, Daisuke Nakajima
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108303- (2022)
The human thyroid receptor (hTR)-antagonist activities of 691 compounds were evaluated using a yeast two-hybrid assay with Saccharomyces cerevisiae Y190 introduced hTRα and coactivator. In parallel, those YTOX tests were conducted to evaluate whethe
Externí odkaz:
https://doaj.org/article/0152ce0e928f4b7c88e4ef6e8906d3e9
Autor:
Dominika Kowalska, Anita Sosnowska, Natalia Bulawska, Maciej Stępnik, Harrie Besselink, Peter Behnisch, Tomasz Puzyn
Publikováno v:
Molecules, Vol 28, Iss 2, p 479 (2023)
In this study, we investigated PFAS (per- and polyfluoroalkyl substances) binding potencies to nuclear hormone receptors (NHRs): peroxisome proliferator-activated receptors (PPARs) α, β, and γ and thyroid hormone receptors (TRs) α and β. We have
Externí odkaz:
https://doaj.org/article/3e4c617fa8df4790b3231bb43c986a7f
Autor:
Farah Kausar
Publikováno v:
Bioscientific Review, Vol 2, Iss 1 (2020)
Thyroid dysfunction alters the physiological events of pregnancy that may have serious outcomes if left untreated. Hyperthyroidism (a thyroid disease) is related to complications during pregnancy. A challenging task for the physician is to correctly
Externí odkaz:
https://doaj.org/article/1deb9ed26b974d6e932e939bbe104b97
Publikováno v:
Environmental Health Perspectives, 1999 Apr 01. 107(4), 273-278.
Externí odkaz:
https://www.jstor.org/stable/3434593
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