Zobrazeno 1 - 10
of 78
pro vyhledávání: '"three prime repair exonuclease 1"'
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy. Its typical neuroimaging features are punctate white matter lesions or pseudotumor alt
Externí odkaz:
https://doaj.org/article/16b7f4c533c44014b35c2614ea27d8b8
Autor:
Faruk Incecik, Sibel Balci, Rabia Miray Kisla Ekinci, Ozlem M Herguner, Atil Bisgin, Mustafa Yilmaz
Publikováno v:
Annals of Indian Academy of Neurology, Vol 23, Iss 5, Pp 699-703 (2020)
Three prime repair exonuclease 1 (TREX1) degrades single- and double-stranded DNA with 3’-5’ exonuclease activity. TREX1 mutations are related to type 1 interferon-mediated autoinflammation owing to accumulated intracellular nucleic acids. Severa
Externí odkaz:
https://doaj.org/article/4b7cfba5ccfb4792ae03363261cd1f54
Autor:
Shu Dai, Zhenhong Zhu, Qian-wei Xiong, Hongliang Xia, Xiangming Yan, Shi-zhong Cai, Wei Liu, Zhou-rui Ma
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
Human melanoma is a highly aggressive type of cancer, causing significant mortalities despite the advances in treatment. Carboplatin is a cisplatin analog necessary for the treatment of various cancers and can also be used to treat human melanoma. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fe3de5246fe2c7cd026ccaeeb38553
http://europepmc.org/articles/PMC8806763
http://europepmc.org/articles/PMC8806763
Autor:
Qilong Wang, Yanze Yang, Mei Du, Jinna Wei, Xianxian Zheng, Zhang Han, Erwei Liu, Xiumei Gao, Yuefei Wang, Patrick Kwabena Oduro
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 50-75 (2022)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling exert essential regulatory function in microbial-and onco-immunology through the induction of cytokines, primarily type I interferons. Recently, the aberrant and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eaf60046ceb32698b7a7ea7c3674b44
http://www.sciencedirect.com/science/article/pii/S2211383521001775
http://www.sciencedirect.com/science/article/pii/S2211383521001775
Autor:
Tao Wang, Yuyan Yang, Xue Zhang, Yuehua Liu, Yaping Liu, Jiaxing Song, Lu Yang, Huilei Miao, Shiyu Zhang
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-8 (2021)
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal
Background Type I interferonopathies are a group of rare autoimmune diseases characterised by excessive activation of type I interferon that leads to disturbances in immune function. Three prime repair exonuclease 1 (TREX1) is an important exonucleas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b79262cda3a2bf5444d7146712e09e
https://doaj.org/article/cc5cd8cdd6f4424c86122fb35818ebf9
https://doaj.org/article/cc5cd8cdd6f4424c86122fb35818ebf9
Akademický článek
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Autor:
Jui Pandhare, Min Li, Nicklas Sapp, Benem-Orom Davids, Chandravanu Dash, Robert Craigie, Prem Prakash, Thomas Hollis, Muthukumar Balasubramaniam, Shalonda M. Ingram
Publikováno v:
J Virol
Three prime repair exonuclease 1 (TREX1) is the most abundant 3′→5′ exonuclease in mammalian cells. It has been suggested that TREX1 degrades HIV-1 DNA to enable the virus to evade the innate immune system. However, the exact role of TREX1 duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c051368f762657b4f1c5315e3a57e8
https://doi.org/10.1128/jvi.00555-21
https://doi.org/10.1128/jvi.00555-21
Publikováno v:
BMC Neurology
BMC Neurology, Vol 21, Iss 1, Pp 1-5 (2021)
BMC Neurology, Vol 21, Iss 1, Pp 1-5 (2021)
Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy. Its typical neuroimaging features are punctate white matter lesions or pseudotumor alterations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d118cc1fee6db60a66f15fc1ca5acc
https://doi.org/10.1186/s12883-021-02250-4
https://doi.org/10.1186/s12883-021-02250-4
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Frontiers in Pediatrics
Frontiers in Pediatrics
TREX1 (three prime repair exonuclease 1) gene encodes DNA 3′ end repair exonuclease that plays an important role in DNA repair. Mutations in TREX1 gene have been identified as the cause of a rare autoimmune neurological disease, Aicardi-Goutières
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf3a5827d906de1290ef6c3e0ac8d62
https://doi.org/10.3389/fped.2021.634281
https://doi.org/10.3389/fped.2021.634281
Autor:
Faruk Incecik, Ozlem M Herguner, Atil Bisgin, Sibel Balci, Rabia Miray Kisla Ekinci, Mustafa Yilmaz
Publikováno v:
Annals of Indian Academy of Neurology
Annals of Indian Academy of Neurology, Vol 23, Iss 5, Pp 699-703 (2020)
Annals of Indian Academy of Neurology, Vol 23, Iss 5, Pp 699-703 (2020)
Three prime repair exonuclease 1 (TREX1) degrades single- and double-stranded DNA with 3’-5’ exonuclease activity. TREX1 mutations are related to type 1 interferon-mediated autoinflammation owing to accumulated intracellular nucleic acids. Severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e8e61159547b355414e59ff652484b
https://doi.org/10.4103/aian.aian_469_18
https://doi.org/10.4103/aian.aian_469_18