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Akademický článek

Structural ultrasound of joints and tendons in healthy children: development of normative data

Autor: Ruth Wittoek, Céline Decock, Nele Dewaele, Lara Arnold, Pieter Baeyens, Ignace De Schrijver, Lisa Pardaens, Ioannis Raftakis, Thomas Renson, Charline Rinkin, Alexander D. J. Thooft, Tine Vanhaverbeke, Caroline Verbist

Publikováno v: Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-8 (2023)

Abstract Background Musculoskeletal ultrasound is a well accessible technique to assess disease activity in children with juvenile idiopathic arthritis. Knowledge of reference values of joint structures is indispensable to differentiate between physi

Externí odkaz: https://doaj.org/article/40b13a976b3a4c129d137ce287a77961

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Akademický článek

GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery

Autor: Loes van Schie, Wander Van Breedam, Charlotte Roels, Bert Schepens, Martin Frank, Ahmad Reza Mehdipour, Bram Laukens, Wim Nerinckx, Francis Santens, Simon Devos, Iebe Rossey, Karel Thooft, Sandrine Vanmarcke, Annelies Van Hecke, Xavier Saelens, Nico Callewaert

Publikováno v: mAbs, Vol 15, Iss 1 (2023)

ABSTRACTAs small and stable high-affinity antigen binders, VHHs boast attractive characteristics both for therapeutic use in various disease indications, and as versatile reagents in research and diagnostics. To further increase the versatility of VH

Externí odkaz: https://doaj.org/article/67952f97f7f1443594a2016e37e133b0

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Akademický článek

Cerebro-spinal fluid glucose and lactate concentrations changes in response to therapies in patIents with primary brain injury: the START-TRIP study

Publikováno v: Critical Care, Vol 27, Iss 1, Pp 1-11 (2023)

Abstract Introduction Altered levels of cerebrospinal fluid (CSF) glucose and lactate concentrations are associated with poor outcomes in acute brain injury patients. However, no data on changes in such metabolites consequently to therapeutic interve

Externí odkaz: https://doaj.org/article/c2ed81f5c0274e3283204443d4d5c798

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Akademický článek

Serum Metabolomic Profiles in Critically Ill Patients with Shock on Admission to the Intensive Care Unit

Autor: Aurélie Thooft, Raphaël Conotte, Jean-Marie Colet, Karim Zouaoui Boudjeltia, Patrick Biston, Michaël Piagnerelli

Publikováno v: Metabolites, Vol 13, Iss 4, p 523 (2023)

Inflammatory processes are common in intensive care (ICU) patients and can induce multiple changes in metabolism, leading to increased risks of morbidity and mortality. Metabolomics enables these modifications to be studied and identifies a patient�

Externí odkaz: https://doaj.org/article/8978ba8ef5184b1c9d15d591ddc5fdba

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