Zobrazeno 1 - 10
of 211
pro vyhledávání: '"thiosemicarbazone derivatives"'
Autor:
Bing Zhao, Xinhui Zhang, Tingting Yu, Ying Liu, Xiaoling Zhang, Yongfang Yao, Xuejian Feng, Hongmin Liu, Dequan Yu, Liying Ma, Shangshang Qin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 203-221 (2021)
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no p
Externí odkaz:
https://doaj.org/article/8b2399cb7ac94e9d919b5377e17e0cde
Autor:
Ximeng Duan, Zhiyu Xie, Liying Ma, Xueyang Jin, Ming Zhang, Yuliang Xu, Yue Liu, Hongxiang Lou, Wenqiang Chang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Metal chelation is generally considered as a promising antifungal approach but its specific mechanisms are unclear. Here, we identify 13 thiosemicarbazone derivatives that exert broad-spectrum antifungal activity with potency comparable or s
Externí odkaz:
https://doaj.org/article/c5a32919efc9471e8fc6532295509d87
Autor:
Mehdi Mousavi, Fereidoon Daryaee, Omid Ranjbaran, Behnam Mohseni, Saeideh Taheri, Abdolreza Hassanzadeh
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 30, Iss 184, Pp 106-118 (2020)
Background and purpose: Nonlinear analysis methods for quantitative structure–activity relationship (QSAR) studies better describe molecular behaviors, than linear analysis. Artificial neural networks are mathematical models and algorithms which im
Externí odkaz:
https://doaj.org/article/6f24075fd5d34654adf530a67e70e59c
Publikováno v:
Molbank, Vol 2021, Iss 4, p M1284 (2021)
Based on recent discoveries concerning the numerous biological properties of thiazolidinones and thiosemicarbazones, new N-substituted heterocyclic derivatives have been designed by combining the indole ring with thioxothiazolidinone, thiazolidinone
Externí odkaz:
https://doaj.org/article/589179aa2e774eb0be6df32d4498f599
Akademický článek
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Akademický článek
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Publikováno v:
Medical Oncology. 39
In this study, firstly, 22 thiosemicarbazone derivatives (3a-y) were synthesized. Then, ADME parameters, pharmacokinetic properties, drug-like structures, and suitability for medicinal chemistry of these molecules were studied theoretically by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c84f6c1ad0209e3a804dc1ca3970369
https://doi.org/10.1007/s12032-022-01784-y
https://doi.org/10.1007/s12032-022-01784-y
Autor:
Xin-Hui Zhang, Hong-Min Liu, Yongfang Yao, Li-Ying Ma, Xue-Jian Feng, Qin Shangshang, Tingting Yu, Bing Zhao, De-Quan Yu, Xiaoling Zhang, Ying Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 203-221 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44e2471539ae24953ab00f10282f4be
http://www.sciencedirect.com/science/article/pii/S2211383520306316
http://www.sciencedirect.com/science/article/pii/S2211383520306316
Akademický článek
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Publikováno v:
Arabian Journal of Chemistry, Vol 9, Iss S2, Pp S1935-S1942 (2016)
The work described in this paper involves the synthesis and structural characterization of Ni(II) complexes derived from dihydroxybenzaldehyde thiosemicarbazones (H3L1, H3L2, H3L3, H3L4) and 1,2-bis(diphenylphosphino)ethane (dppe). Ligands and their
Externí odkaz:
https://doaj.org/article/3b75349078054cdbacaf1e39bfb6fdda