Zobrazeno 1 - 10
of 154
pro vyhledávání: '"thioredoxin-interacting protein (TXNIP)"'
Autor:
Zheng-Lin Dong, Xin Jiao, Zeng-Guang Wang, Kai Yuan, Yi-Qi Yang, Yao Wang, Yun-Tao Li, Tian-Chang Wang, Tian-You Kan, Jian Wang, Hai-Rong Tao
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background Intervertebral disc degeneration (IVDD) is a multifaceted condition characterized by heterogeneity, wherein the balance between catabolism and anabolism in the extracellular matrix of nucleus pulposus (NP) cells plays a central ro
Externí odkaz:
https://doaj.org/article/677cbfe15a4e4a319d9e5ee7f698da37
Autor:
Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, Yuji Hattori, Yuya Ishihara, Nobuyuki Hamajima, Shuji Hashimoto, Koji Suzuki
Publikováno v:
Endocrine Journal, Vol 71, Iss 6, Pp 593-601 (2024)
Thioredoxin-interacting protein (TXNIP) plays an important role in glucose metabolism, and its expression is regulated by DNA methylation (DNAm). Although the association between TXNIP DNAm and type 2 diabetes mellitus has been demonstrated in studie
Externí odkaz:
https://doaj.org/article/c887e932ac4a41ebb7551cade7f5237d
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/39f3e5c1d8e7489eaefb6cae5d4f097f
Akademický článek
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Akademický článek
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Autor:
Yongshun Wang, Jingjin Liu, Huadong Liu, Xin Sun, Ruimian Chen, Bihong Liao, Xiaoyi Zeng, Xiaoxin Zhang, Shaohong Dong, Zhengyuan Xia, Jie Yuan
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Endothelial cells are highly sensitive to hemodynamic shear stresses, which act in the blood flow’s direction on the blood vessel’s luminal surface. Thus, endothelial cells on that surface are exposed to various physiological and pathological sti
Externí odkaz:
https://doaj.org/article/b09044c3f6f54148b8b48165a8b58e88
Autor:
Fengyu Cheng, Nan Wang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Inflammasomes are cytoplasmic complexes that form in response to exogenous microbial invasions and endogenous damage signals. Among the known inflammasomes, the activation of the NACHT (NAIP, CIITA, HET-E, and TP1 domain), leucine-rich repeat, and py
Externí odkaz:
https://doaj.org/article/5ea7524077cb44cb9e507e106d07172f
Autor:
Jung-Hwa Han, Dae-Hwan Nam, Seon-Hui Kim, Ae-Rang Hwang, So-Young Park, Jae Hyang Lim, Chang-Hoon Woo
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 458 (2023)
TXNIP is a critical regulator of glucose homeostasis, fatty acid synthesis, and cholesterol accumulation in the liver, and it has been reported that metabolic diseases, such as obesity, atherosclerosis, hyperlipidemia, type 2 diabetes, and nonalcohol
Externí odkaz:
https://doaj.org/article/bbe07d16e6264e0e9645378060c01b0d
Autor:
Ting Xue, Xiaodan Wang, Ying Hu, Ying Cheng, Han Li, Yuan Shi, Lijun Wang, Dongmin Yin, Donghong Cui
Publikováno v:
Brain Sciences, Vol 12, Iss 10, p 1395 (2022)
The brain is susceptible to perturbations of redox balance, affecting neurogenesis and increasing the risks of psychiatric disorders. Thioredoxin-interacting protein (TXNIP) is an endogenous inhibitor of the thioredoxin antioxidant system. Its deleti
Externí odkaz:
https://doaj.org/article/3f778f047dca4e6fb238849052e4829a
Akademický článek
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