Analysis of Protection and Immune Response against Teladorsagia circumcincta in Goats Immunised with Thiol-Binding Proteins from Adult Worms

Autor: Leire Ortega, Jessica Quesada, Antonio Ruiz, Magnolia María Conde-Felipe, Otilia Ferrer, María del Carmen Muñoz, José Adrián Molina, Francisco Rodríguez, José Manuel Molina

Publikováno v: Vaccines, Vol 12, Iss 4, p 437 (2024)

In view of the increasing occurrence of anthelmintic-resistant strains of gastrointestinal nematodes in ruminants, various alternative control strategies have been investigated, such as those based on the induction of protective immune responses by i

Externí odkaz: https://doaj.org/article/5e356fa9f6de4d1abf18a641ff490f26

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Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES)

Autor: A. W. C. A. Cornelissen, E. de Vries, Nicole Bakker, Ana Patrícia Yatsuda, Dave P. Knox, Lonneke Vervelde, K Kanobana

Publikováno v: Bakker, N, Vervelde, L, Kanobana, K, Knox, DP, Cornelissen, AWCA, de Vries, E & Yatsuda, AP 2004, ' Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES) ', Vaccine, vol. 22, no. 5-6, pp. 618-628 . https://doi.org/10.1016/j.vaccine.2003.08.025

Fractionated excretory/secretory products (ES) of adult Haemonchus contortus were evaluated as protective antigens. The proteins were successively eluted from a Thiol Sepharose column using 25 mM cysteine followed by 25 mM Dl-dithiothreitol (DTT). Sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188d6b41efbb4e317df1730ba9e0071b
https://pubmed.ncbi.nlm.nih.gov/14741153

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