Zobrazeno 1 - 10
of 2 733
pro vyhledávání: '"therapy response"'
Autor:
Qinglin Tan, Peiliang Kong, Guobiao Chen, Yanmin Cai, Kejun Liu, Chen Chen, Huiting Mo, Yuancheng Huang, Jianming Lu, Yifen Wu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Trophinin Associated Protein (TROAP) has been implicated in some tumors, yet its role in renal cell carcinoma (RCC) remains underexplored. This study aims to elucidate the prognostic and therapeutic implications of TROAP in RCC, e
Externí odkaz:
https://doaj.org/article/2780cfdf2cc94faf9f7687ddda80ffde
Autor:
Kai Li, Rui Wang, Guo-Wei Liu, Zi-Yang Peng, Ji-Chang Wang, Guo-Dong Xiao, Shou-Ching Tang, Ning Du, Jia Zhang, Jing Zhang, Hong Ren, Xin Sun, Yi-Ping Yang, Da-Peng Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The tumor microenvironment (TME) plays a pivotal role in the onset, progression, and treatment response of cancer. Among the various components of the TME, cancer-associated fibroblasts (CAFs) are key regulators of both immune and non-immune
Externí odkaz:
https://doaj.org/article/f8c95d8abdd3488fa1e2f3b9f93536ee
Autor:
Xi Zhang, Rui Chen, Zirong Huo, Wenqing Li, Mengju Jiang, Guodong Su, Yuru Liu, Yu Cai, Wuhao Huang, Yuyan Xiong, Shengguang Wang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Despite the improved survival observed in PD-1/PD-L1 blockade therapy, a substantial proportion of cancer patients, including those with non-small cell lung cancer (NSCLC), still lack a response. Methods Transcriptomic profiling w
Externí odkaz:
https://doaj.org/article/9a46a025d65b4900ac6cb59d8d129582
Autor:
Eva Chrenková, Hana Študentová, Kateřina Holá, Zuzana Kahounová, Romana Hendrychová, Karel Souček, Jan Bouchal
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundProstate cancer is the second leading cause of male cancer-related deaths in Western countries, which is predominantly attributed to the metastatic castration-resistant stage of the disease (CRPC). There is an urgent need for better prognos
Externí odkaz:
https://doaj.org/article/163eb8b28e5347c29d9888fde0a8ca1e
Autor:
Anikó E. Malik, Drew Slauenwhite, Sarah M. McAlpine, John G. Hanly, Jean S. Marshall, Thomas B. Issekutz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveAntigen-presenting dendritic cells (DCs) and monocytes play an essential role in rheumatoid arthritis (RA) pathogenesis, however, their tolerogenic potential remains unclear. Herein, the tolerogenic profiles of DCs are characterized in treat
Externí odkaz:
https://doaj.org/article/ada887f28e424002807018d3e254353f
Autor:
Georgios Sidiropoulos, Paschalis Karakasis, Antonios Antoniadis, Athanasios Saplaouras, Theodoros Karamitsos, Nikolaos Fragakis
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 14, p 4173 (2024)
Background: Right ventricular (RV) failure is an important predicting factor regarding overall and event-free survival regardless of baseline left ventricular (LV) function in patients with severe heart failure (HF). Previous studies have indicated t
Externí odkaz:
https://doaj.org/article/ea534743645c4a65bdce12529f420208
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27011- (2024)
Thioredoxin reductase 1 (Txnrd1) is known to have prognostic significance in a subset of breast cancer patients. Despite the pivotal role of Txnrd1 in regulating several cellular and physiological processes in cancer progression and metastasis, its c
Externí odkaz:
https://doaj.org/article/31d68328d00b48ec89fb7e06f1957c99
Autor:
Maria Tamara Neves Pereira, Mariana Tinoco, Margarida Castro, Luísa Pinheiro, Filipa Cardoso, Lucy Calvo, Sílvia Ribeiro, Vitor Monteiro, Victor Sanfins, António Lourenço
Publikováno v:
Monaldi Archives for Chest Disease (2024)
Cardiac resynchronization therapy (CRT) is an effective treatment for selected heart failure (HF) patients. Although transvenous implantation is the standard method, it is not feasible in some patients, so the epicardial lead emerges as an alternativ
Externí odkaz:
https://doaj.org/article/b428770b26ec4d7ca78055dfaeb7598a
Autor:
Marco G. Hermann, Nils Schröter, Alexander Rau, Marco Reisert, Nadja Jarc, Michel Rijntjes, Jonas A. Hosp, Peter C. Reinacher, Wolfgang H. Jost, Horst Urbach, Cornelius Weiller, Volker A. Coenen, Bastian E.A. Sajonz
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103607- (2024)
Background: Nigrostriatal microstructural integrity has been suggested as a biomarker for levodopa response in Parkinson’s disease (PD), which is a strong predictor for motor response to deep brain stimulation (DBS) of the subthalamic nucleus (STN)
Externí odkaz:
https://doaj.org/article/cde4b460a77d45d1b4cbc0cd593af5e3
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
ObjectiveThis retrospective study aims to evaluate the therapeutic effect of varying dosages of adjuvant radioactive iodine (RAI) therapy on intermediate-risk papillary thyroid carcinoma (PTC) patients.MethodsThis retrospective study involved a total
Externí odkaz:
https://doaj.org/article/c44c2cf1613248be9694cda790d650db