Zobrazeno 1 - 10
of 877
pro vyhledávání: '"therapeutic vaccination"'
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1179 (2024)
Cutaneous leishmaniasis (CL), caused by protozoan parasites of the Leishmania genus, is prevalent in tropical and subtropical regions, with important morbidity, particularly in low- to middle-income countries. Current systemic treatments, including p
Externí odkaz:
https://doaj.org/article/f52174d95af042d7a4079900e683202c
Autor:
Molly R. Braun, Anne C. Moore, Jonathan D. Lindbloom, Katherine A. Hodgson, Emery G. Dora, Sean N. Tucker
Publikováno v:
Vaccines, Vol 12, Iss 9, p 955 (2024)
Therapeutic vaccination can harness the body’s cellular immune system to target and destroy cancerous cells. Several treatment options are available to eliminate pre-cancerous and cancerous lesions caused by human papillomaviruses (HPV), but may no
Externí odkaz:
https://doaj.org/article/13084199717a41a68551113613ad3ced
Autor:
Max Augustin, Melanie Stecher, Hauke Wüstenberg, Veronica Di Cristanziano, Ute Sandaradura de Silva, Lea Katharina Picard, Elisabeth Pracht, Dominic Rauschning, Henning Gruell, Florian Klein, Christoph Wenisch, Michael Hallek, Philipp Schommers, Clara Lehmann
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundWhile the short-term symptoms of post-COVID syndromes (PCS) are well-known, the long-term clinical characteristics, risk factors and outcomes of PCS remain unclear. Moreover, there is ongoing discussion about the effectiveness of post-infec
Externí odkaz:
https://doaj.org/article/cd68ffa85084495d8def15fe468e058c
Autor:
Diahann T. S. L. Jansen, Monique T. A. de Beijer, Robbie J. Luijten, Kitty Kwappenberg, Anna-Sophia Wiekmeijer, Amy L. Kessler, Roel F. A. Pieterman, Rachid Bouzid, Willem-Jan Krebber, Robert A. de Man, Cornelis J. M. Melief, Sonja I. Buschow
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTherapeutic vaccination based on synthetic long peptides (SLP®) containing both CD4+ and CD8+ T cell epitopes is a promising treatment strategy for chronic hepatitis B infection (cHBV).MethodsWe designed SLPs for three HBV proteins, HBcA
Externí odkaz:
https://doaj.org/article/42979833c13449608bd111357e727466
Autor:
Dorien De Pooter, Wim Pierson, Soheil Pourshahian, Koen Dockx, Ben De Clerck, Isabel Najera, Heather Davis, Ellen Van Gulck, Daniel Boden
Publikováno v:
Vaccines, Vol 12, Iss 3, p 237 (2024)
Chronic infection with hepatitis B virus (HBV) develops in millions of patients per year, despite the availability of effective prophylactic vaccines. Patients who resolve acute HBV infection develop HBV-specific polyfunctional T cells accompanied by
Externí odkaz:
https://doaj.org/article/df00572e29d84e5eb22d4366e69e6a16
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionFor complete or functional cure of hepatitis B virus (HBV) infection, application of immunotherapy is now being attempted. Recently, we reported that a 6-mer hepatitis B virus (HBV)-derived peptide, Poly6, exerts a strong anticancer effec
Externí odkaz:
https://doaj.org/article/90c20610facd42d78d3066b0fddbc4d9
Autor:
David Repáraz, Marta Ruiz, Leyre Silva, Belén Aparicio, Josune Egea, Elizabeth Guruceaga, Daniel Ajona, Yaiza Senent, Enrique Conde, Flor Navarro, Sergio Barace, Diego Alignani, Sandra Hervás-Stubbs, Juan José Lasarte, Diana Llopiz, Pablo Sarobe
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Vaccination using optimized strategies may increase response rates to immune checkpoint inhibitors (ICI) in some tumors. To enhance vaccine potency and improve thus responses to ICI, we analyzed the gene expression profile of an immunosuppressive den
Externí odkaz:
https://doaj.org/article/53cc78736e214f2f9fa14856330d5191
Akademický článek
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Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1545-1554 (2021)
The prolonged viral antigen stimulation is the driving force for the development of immune tolerance to chronic hepatitis B virus (HBV) infection. The sustained reduction of viral proteins may allow for the recovery and efficient activation of HBV-sp
Externí odkaz:
https://doaj.org/article/c22cb7acfba643bc8b15345d3d067874
Akademický článek
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