Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment

Autor: Britt T.J. van Hagen, Nick P. van Goethem, Ellis Nelissen, Dean Paes, Karin Koymans, Scott van Hoof, Rudy Schreiber, Mark Varney, Adrian Newman-Tancredi, Jos Prickaerts

Publikováno v: Molecular and Cellular Neuroscience, 120:103719. Elsevier Science
Molecular and cellular neuroscience, 120:103719. Academic Press Inc.
Molecular and cellular neuroscience 120, 103719 (2022). doi:10.1016/j.mcn.2022.103719

Pattern separation is a hippocampal process in which highly similar stimuli are recognized as separate representations, and deficits could lead to memory impairments in neuropsychiatric disorders such as schizophrenia. The 5-HT1A receptor (5-HT1AR) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b78c02d55a363b652798063571d520
https://doi.org/10.1016/j.mcn.2022.103719