Zobrazeno 1 - 10
of 2 403
pro vyhledávání: '"therapeutic resistance"'
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Developing resistance to cancer treatments is a major challenge, often leading to disease recurrence and metastasis. Understanding the underlying mechanisms of therapeutic resistance is critical for developing effective strategies. O-GlcNAcy
Externí odkaz:
https://doaj.org/article/72fc510600394a2cb0ee3cd1f4cf80bb
Autor:
Chih-Hsiung Hsieh, Pei-Shiuan Ho, Wen-Lun Wang, Fu-Hsuan Shih, Chen-Tai Hong, Pei-Wen Wang, Dar-Bin Shieh, Wei-Lun Chang, Yi-Ching Wang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Stromal fibrosis is highly associated with therapeutic resistance and poor survival in esophageal squamous cell carcinoma (ESCC) patients. Low expression of plasma gelsolin (pGSN), a serum abundant protein, has been found to corre
Externí odkaz:
https://doaj.org/article/91f79a3af5354b18b038a5a565c91bb0
Autor:
Aiman Al-Ruwishan, Bushra Amer, Ahmed Salem, Ahmed Abdi, Namoonga Chimpandu, Abdelmonem Esa, Alexandros Melemenis, Muhammad Zubair Saleem, Roselit Mathew, Yaser Gamallat
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8340-8367 (2024)
Despite recent advancements in technology, breast cancer still poses a significant threat, often resulting in fatal consequences. While early detection and treatments have shown some promise, many breast cancer patients continue to struggle with the
Externí odkaz:
https://doaj.org/article/b2c40c9c36904375920d6e62cd7b6769
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract The resistance of cancer cells to treatment significantly impedes the success of therapy, leading to the recurrence of various types of cancers. Understanding the specific mechanisms of therapy resistance may offer novel approaches for allev
Externí odkaz:
https://doaj.org/article/6ebb5d0783234eec89c936b4f7ad4a5b
Autor:
Jianing Li, Yongsheng Zhang, Tong Fu, Guoli Xing, Hongbo Cai, Kaiqing Li, Yutong Xu, Ying Tong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundT cell receptor (TCR)-T cell therapy is an innovative form of cancer immunotherapy that genetically modifies patients’ T cells to target and destroy cancer cells. However, the current status of clinical trials of TCR-T cell therapy for th
Externí odkaz:
https://doaj.org/article/55b6fca0ec8141f7972064a2542e3996
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-28 (2024)
Abstract Cancer therapeutic resistance remains a significant challenge in the pursuit of effective treatment strategies. Circular RNAs (circRNAs), a class of non-coding RNAs, have recently emerged as key regulators of various biological processes, in
Externí odkaz:
https://doaj.org/article/e11adeae289d4df9a2ec29d23ec0e983
Autor:
Haiyan E. Liu, Meghah Vuppalapaty, Christian R. Hoerner, Colin P. Bergstrom, Michael Chiu, Clementine Lemaire, James Che, Amanpreet Kaur, Adam Dimmick, Sean Liu, Thomas J. Metzner, Menna Araya, Steve Crouse, Markus Sprenger-Haussels, Martin Schlumpberger, John T. Leppert, Siegfried Hauch, Elodie Sollier, Alice C. Fan
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Therapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor inhibitors (ARIs) and prostate-specific membrane antigen (PSMA). Having the ability to detec
Externí odkaz:
https://doaj.org/article/f147876cb7db462d84fa5bc412a8c4d4
Autor:
Fei Luo, Mingda Zhang, Bowen Sun, Chenxin Xu, Yi Yang, Yingwen Zhang, Shanshan Li, Guoyu Chen, Ceshi Chen, Yanxin Li, Haizhong Feng
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Cancer stem-like cell is a key barrier for therapeutic resistance and metastasis in various cancers, including breast cancer, yet the underlying mechanisms are still elusive. Through a genome-wide lncRNA expression profiling, we i
Externí odkaz:
https://doaj.org/article/d683b299b311482783d9ef43f7f2af04
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background Immunotherapy (IO) plus tyrosine kinase inhibitor (TKI) therapy is the first-line recommendation for advanced renal cell carcinoma (RCC), but no biomarker has been approved for it. Annexin A2 (ANXA2) can induce immune escape in tu
Externí odkaz:
https://doaj.org/article/2c762b09099d45d6942ed545c5610751
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract Cancer stem cells (CSCs) are a small subset of tumor cells, efficient in self‐renewal within the tumor and also play a vital role in cancer resistance and metastasis. Recent cancer research has focused on exosomes, a tiny subpopulation of
Externí odkaz:
https://doaj.org/article/11587f8c7e804a368cca146d7665166e