Zobrazeno 1 - 10
of 806
pro vyhledávání: '"therapeutic equivalence"'
Publikováno v:
RUDN Journal of Law, Vol 28, Iss 4, Pp 875-891 (2024)
Due to restrictions on importing medicines from abroad, the domestic pharmaceutical industry is shifting its focus towards the development and manufacturing generic drugs - medications containing a pharmacological substance identical to the original
Externí odkaz:
https://doaj.org/article/dfc7bd182f0f41b0964e31202d994566
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 20, Iss 4, Pp 433-443 (2024)
The article defines the original drug (OD) and examines the history of the appearance of generic drugs (GD), as well as the evolution of views to prove their bioequivalence to OD. The question is considered to what extent pharmacokinetic equivalence
Externí odkaz:
https://doaj.org/article/90292c4341a74f9f9576ec1cdc3666e4
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Recent advances in synthetic drug manufacturing have introduced a new dynamic to the European regulatory system, with chemically synthesized polypeptide products using biological originator products as their reference medicine. Whereas biosimilars ar
Externí odkaz:
https://doaj.org/article/492c4dcbe04b41718470cc9df0ffdd3c
Autor:
Jiri Grim, MD, PhD, Marianna Armogida, MD, Preeti Kachroo, BAMS, MD(AM), Kamran Siddiqui, MBBS, MBA, Mauro Cavinato, PhD, Mako Araga, MS
Publikováno v:
Current Therapeutic Research, Vol 100, Iss , Pp 100734- (2024)
ABSTRACT: Background: A new oral paracetamol formulation with the same paracetamol quantity (24 mg/mL) as a marketed formulation but with finer active ingredient particle size and lower amounts of maltitol (5.85 g/dose in the test formulation vs 7.25
Externí odkaz:
https://doaj.org/article/c24be78049ce4cb49ea62d121639df34
Publikováno v:
Neurology International, Vol 14, Iss 1, Pp 271-283 (2022)
The brand interchangeability of antiepileptic drugs (AEDs) is a topic of debate, especially regarding their therapeutic equivalence. This study evaluates the efficacy and tolerability of generic levetiracetam compared to the brand-name equivalent in
Externí odkaz:
https://doaj.org/article/a2321e6fb87d4cd68385a4adfe3438d1
Publikováno v:
Неврология, нейропсихиатрия, психосоматика, Vol 13, Iss 6, Pp 98-104 (2021)
The review discusses the interchangeability of medications, approaches to the registration of original and generic drugs, and types of their equivalence, as well as problems with generics in clinical practice. Results of pharmacoepidemiological studi
Externí odkaz:
https://doaj.org/article/3b9d5039cf8f446993cedb618f7179fd
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 11, Iss 4, Pp 228-238 (2021)
Evolution of knowledge about pharmacokinetics and pharmacodynamics of locally acting products, and an increase in the number of generics and medicines under development have laid the ground for the development of new scientific approaches to planning
Externí odkaz:
https://doaj.org/article/baba2b84c4db49889665ee128e817deb
Autor:
Soo Kun Lim, Bak Leong Goh, Ravindran Visvanathan, Su Hyun Kim, Jin Seok Jeon, Sung Gyun Kim, Jae Hyun Chang, Chun Soo Lim, Zaki Morad
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Erythropoietin stimulating agent (ESA) has been standard of care in treating renal anaemia for the past 20 years. Many patients have limited access to ESA in view of long-term costs leading to suboptimal ESA dosage. Biosimilar epo
Externí odkaz:
https://doaj.org/article/a13faceccad049b6924089674f593de5
Autor:
Jong Man Kim, Pyoung-Jae Park, Geun Hong, Dong Jin Joo, Kwan Woo Kim, Je Ho Ryu, Young Seok Han, Jai Young Cho, Gi-Won Song, Bong-Wan Kim, Dong-Sik Kim, Seong Hoon Kim, Sang Tae Choi, Young Kyoung You, Kyung-Suk Suh, Yang-Won Na, Koo Jeong Kang, Jae-Won Joh
Publikováno v:
Korean Journal of Transplantation, Vol 35, Iss 3, Pp 168-176 (2021)
Background : Once-daily tacrolimus reduces non-compliance relative to twice-daily tacrolimus. However, little is known about the safety and efficacy of conversion from twice-daily tacrolimus to generic once-daily tacrolimus in liver transplantation (
Externí odkaz:
https://doaj.org/article/875cebc3b61e467cabf331fc49306d14
Autor:
Minish Jain, Sharad Desai, Rajnish Nagarkar, Rakesh Neve, Unmesh Takalkar, Dhananjay Bakhle, Chirag Shah
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 16, Iss 8, Pp XC01-XC07 (2022)
Introduction: Pegfilgrastim is indicated in patients receiving myelosuppressive anticancer drugs to reduce the Duration of Severe Neutropenia (DSN) and incidence of Febrile Neutropenia (FN). The efficacy and safety of a proposed Pegfilgrastim biosimi
Externí odkaz:
https://doaj.org/article/9b55a14751e540a387707e2304f95a66