Zobrazeno 1 - 10
of 4 505
pro vyhledávání: '"the forced swim test"'
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 38, Iss 1 (2024)
Acetylcholinesterase inhibitors (AChEIs) are drugs that enhance cholinergic neuro-transmission and are used for the treatment of Alzheimer’s disease and myasthenia gravis. Common AChEIs include rivastigmine, donepezil and galantamine (GAL), but the
Externí odkaz:
https://doaj.org/article/a5a283a085034d828ddf35935f9dfff5
Synergistic antidepressant-like effect of xylopic acid co-administered with selected antidepressants
Autor:
Charles Kwaku Benneh, Wonder Kofi Mensah Abotsi, Robert Peter Biney, Priscilla Kolibea Mante, Mustapha Kobina Abeka, Augustine Tandoh, Eric Woode
Publikováno v:
IBRO Neuroscience Reports, Vol 16, Iss , Pp 329-335 (2024)
Background: Xylopic acid (XA), a kaurene diterpene from the dried fruits of Xylopia aethiopica, has anxiolytic- and antidepressant-like activity in mice and zebrafish. We aimed to assess the potential synergistic antidepressant-like effects of XA whe
Externí odkaz:
https://doaj.org/article/4797d0ff48d3474698cfd2a16423cdf5
Publikováno v:
Scientific African, Vol 25, Iss , Pp e02267- (2024)
Depression is a major world health issue. Though conventional antidepressants are employed for its management, they are fraught with inconsistent efficacy and untoward side effects. Therefore, finding alternative medicines for depression treatment is
Externí odkaz:
https://doaj.org/article/d18374418ac74553ad6d6c2ede0471fb
Autor:
Widjiati Widjiati, Epy Muhammad Luqman, Suryo Kuntjorodjakti, Aulanni'am Aulanni'am, Zahra Shabira, Sultan Fadhilla Taqwa, Riski Lesta Mega, Dean Chou, Ahmad Shofy Mubarak, Viski Fitri Hendrawan
Publikováno v:
Open Veterinary Journal, Vol 14, Iss 2, Pp 738-742 (2024)
Background: Chronic physical stress has many effects on the nervous system and can cause structural changes in different parts of the brain and hemomodulatory, including hormonal. Current pharmacotherapeutic treatments have limited efficacy and are a
Externí odkaz:
https://doaj.org/article/31a9dd41f2ab4660b6720c2e7d293416
Akademický článek
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Publikováno v:
In Medical Journal Armed Forces India October 2023
Akademický článek
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Autor:
Pushpa V. H., Jayanthi M. K., Rashmi H. R., Veeresh Kumar N. Shivamurthy, Shashank M. Patil, Prithvi S. Shirahatti, Ramith Ramu
Publikováno v:
Pharmaceutical Biology, Vol 60, Iss 1, Pp 1656-1668 (2022)
Context Michelia champaca L. (Magnoliaceae) has been known since ancient times for its rich medicinal properties.Objective The ethanol extract of Michelia champaca leaves (EEMC) was evaluated on depression and anxiety using in vivo and in silico stud
Externí odkaz:
https://doaj.org/article/c1a8013d5b224a459997e7119b30caa1
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 11, Pp 1589-1602 (2022)
Purpose: The aim of this study was to design fast dissolving tablets (FDT) of the anti –psychiatric drug haloperidol in solid dispersion forms as a way to enhance its dissolution profile and anti-psychiatric effect. Methods: Solubility studies of h
Externí odkaz:
https://doaj.org/article/b15ac14e573648588c374bad16e575d0
Autor:
Christiane Brandwein, Cathalijn H.C. Leenaars, Laura Becker, Natascha Pfeiffer, Ana-Maria Iorgu, Melissa Hahn, Gaia A. Vairani, Lars Lewejohann, André Bleich, Anne S. Mallien, Peter Gass
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106917- (2023)
As depression is projected to become the leading mental disease burden globally by 2030, understanding the underlying pathology, as well as screening potential anti-depressants with a higher efficacy, faster onset of action, and/or fewer side-effects
Externí odkaz:
https://doaj.org/article/0fd7811df4754f24849ecd19164f9ef6