Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation

Autor: Philipp Adams, Gilles Iserentant, Jean-Yves Servais, Linos Vandekerckhove, Guido Vanham, Carole Seguin-Devaux, the PhenoCure Study Group

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

Antiretroviral therapy (ART) is not curative as HIV-1 persists in long-lived viral reservoirs. Consequently, patients are dependent on life-long drug adherence with possible side effects. To overcome these limitations strategies of a functional cure

Externí odkaz: https://doaj.org/article/2539b03dba354e79b24b2c8006d41d67

Cytotoxic CD8+ T Cells Expressing CXCR5 Are Detectable in HIV-1 Elite Controllers After Prolonged In Vitro Peptide Stimulation.

Autor: Adams P; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.; Departments of Biomedical and Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Iserentant G; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg., Servais JY; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg., Vandekerckhove L; Department of Internal Medicine, Ghent University, Ghent, Belgium., Vanham G; Departments of Biomedical and Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Seguin-Devaux C; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Feb 24; Vol. 11, pp. 622343. Date of Electronic Publication: 2021 Feb 24 (Print Publication: 2020).