Zobrazeno 1 - 10
of 98
pro vyhledávání: '"the Diabetes Prevention Program Research Group"'
Autor:
Diabetes Prevention Program Research Group, Jose C. Florez, Toni I. Pollin, William C. Knowler, Steven E. Kahn, Robert L. Hanson, Paul W. Franks, L. Keoki Williams, Shujie Xiao, Adriana M. Hung, Ayush Giri, Kathleen M. Giacomini, Ewan R. Pearson, Sook Wah Yee, Adem Y. Dawed, Qing Pan, Josep M. Mercader, Maegan Harden, Jennifer N. Todd, Ling Chen, Shylaja Srinivasan, Kathleen A. Jablonski, James A. Perry, Josephine Li
Genome-wide significant loci for metformin response in type 2 diabetes reported elsewhere have not replicated in the Diabetes Prevention Program (DPP). To assess pharmacogenetic interactions in pre-diabetes, we conducted a genome-wide association stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6390e02ff019f014b64ab35178d8cd
https://doi.org/10.2337/figshare.21719837
https://doi.org/10.2337/figshare.21719837
Autor:
the Diabetes Prevention Program Research Group, David M. Nathan, Mathias Schlögl, Christine Darwin, Xavier Pi-Sunyer, Ronald B. Goldberg, Barbara Blodi, Emily Y. Chew, Dana Dabelea, Emily B. Schroeder, William C. Knowler, Qing Pan, Neil H. White
OBJECTIVE: To determine whether interventions that slow or prevent the development of type 2 diabetes mellitus in those at risk reduce the subsequent prevalence of diabetic retinopathy. RESEARCH DESIGN AND METHODS: The Diabetes Prevention Program (DP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442d9fcc99adfdcc7eb5661ba1c80819
https://doi.org/10.2337/figshare.19638765
https://doi.org/10.2337/figshare.19638765
Autor:
Goldberg, Ronald B, Orchard, Trevor J, Crandall, Jill P, Boyko, Edward J, Budoff, Matthew, Dabelea, Dana, Gadde, Kishore M, Knowler, William C, Lee, Christine G, Nathan, David M, Watson, Karol, Temprosa, Marinella, Diabetes Prevention Program Research Group
Publikováno v:
Circulation, vol 145, iss 22
BackgroundLifestyle intervention and metformin have been shown to prevent diabetes; however, their efficacy in preventing cardiovascular disease associated with the development of diabetes is unclear. We examined whether these interventions reduced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::5c853a99ae71bc65e1de71a9ea93c8ec
https://escholarship.org/uc/item/3r06g7r1
https://escholarship.org/uc/item/3r06g7r1
Autor:
Lee, Christine G, Heckman-Stoddard, Brandy, Dabelea, Dana, Gadde, Kishore M, Ehrmann, David, Ford, Leslie, Prorok, Philip, Boyko, Edward J, Pi-Sunyer, Xavier, Wallia, Amisha, Knowler, William C, Crandall, Jill P, Temprosa, Marinella, Diabetes Prevention Program Research Group
Publikováno v:
Diabetes care, vol 44, iss 12
ObjectiveTo determine whether metformin or lifestyle modification can lower rates of all-cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study.Research design and methodsFrom 1996 to 1999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6c0c7636340734bf1defed8b7a09e975
https://escholarship.org/uc/item/7tz8r11k
https://escholarship.org/uc/item/7tz8r11k
Autor:
the Diabetes Prevention Program Research Group, Marinella Temprosa, Jill P. Crandall, William C. Knowler, Amisha Wallia, Xavier Pi-Sunyer, Edward J. Boyko, Philip Prorok, Leslie Ford, David Ehrmann, Kishore M. Gadde, Dana Dabelea, Brandy Heckman-Stoddard, Christine G. Lee
Objective: To determine whether metformin or lifestyle modification can lower rates of all-cause and cause-specific mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. Research Design and Methods: From 1996-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51119dfaf2cdd1e8429b8021b118f58a
https://doi.org/10.2337/figshare.16652587.v1
https://doi.org/10.2337/figshare.16652587.v1
Publikováno v:
In The Lancet 2009 374(9702):1677-1686
Autor:
Jose C Florez, Kathleen A Jablonski, Jarred B McAteer, Paul W Franks, Clinton C Mason, Kieren Mather, Edward Horton, Ronald Goldberg, Dana Dabelea, Steven E Kahn, Richard F Arakaki, Alan R Shuldiner, William C Knowler, Diabetes Prevention Program Research Group
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44424 (2012)
Common genetic variants have been recently associated with fasting glucose and insulin levels in white populations. Whether these associations replicate in pre-diabetes is not known. We extended these findings to the Diabetes Prevention Program, a cl
Externí odkaz:
https://doaj.org/article/184f6b243eb44be98ad6f7224b7b3386
Autor:
Toni I Pollin, Tamara Isakova, Kathleen A Jablonski, Paul I W de Bakker, Andrew Taylor, Jarred McAteer, Qing Pan, Edward S Horton, Linda M Delahanty, David Altshuler, Alan R Shuldiner, Ronald B Goldberg, Jose C Florez, Paul W Franks, Diabetes Prevention Program Research Group
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002895 (2012)
Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes
Externí odkaz:
https://doaj.org/article/1511d67fc92e4fdfa24084c24f50a268
Autor:
Jeanne M McCaffery, Kathleen A Jablonski, Paul W Franks, Sam Dagogo-Jack, Rena R Wing, William C Knowler, Linda Delahanty, Dana Dabelea, Richard Hamman, Alan R Shuldiner, Jose C Florez, Diabetes Prevention Program Research Group
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21518 (2011)
TCF7L2 variants have been associated with type 2 diabetes, body mass index (BMI), and deficits in proinsulin processing and insulin secretion. Here we sought to test whether these effects were apparent in high-risk individuals and modify treatment re
Externí odkaz:
https://doaj.org/article/35d76592b8954f64bdc43b0944fe37cb
Autor:
Mingjian Shi, Chuan Wang, Hao Mei, Temprosa, Marinella, Florez, Jose C., Tripputi, Mark, Merino, Jordi, Lipworth, Loren, Xiao-Ou Shu, Gerszten, Robert E., Wang, Thomas J., Beckman, Joshua A., Gamboa, Jorge L., Mosley, Jonathan D., Ferguson, Jane F., Shi, Mingjian, Wang, Chuan, Mei, Hao, Shu, Xiao-Ou, Diabetes Prevention Program Research Group
Publikováno v:
Journal of the American Heart Association; 6/7/2022, Vol. 11 Issue 11, p1-12, 24p