Zobrazeno 1 - 10 of 15 pro vyhledávání: '"the COVID-19 Immunoprofiling Team"'
1
Akademický článek
The single-dose Janssen Ad26.COV2.S COVID-19 vaccine elicited robust and persistent anti-spike IgG antibody responses in a 12-month Ugandan cohort
Autor: Jennifer Serwanga, Laban Kato, Gerald Kevin Oluka, Violet Ankunda, Jackson Sembera, Claire Baine, Isaac Kitabye, Angela Namuyanja, Solomon Opio, Joseph Ssebwana Katende, Peter Ejou, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionThe study investigation examined the immune response to the Janssen Ad26.COV2.S COVID-19 vaccine within a Ugandan cohort, specifically targeting antibodies directed against spike (S) and nucleocapsid (N) proteins. We aimed to examine the
Externí odkaz: https://doaj.org/article/1db485c38c5a405ea296012ef5315fec
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2
Akademický článek
The subdued post-boost spike-directed secondary IgG antibody response in Ugandan recipients of the Pfizer-BioNTech BNT162b2 vaccine has implications for local vaccination policies
Autor: Violet Ankunda, Joseph Ssebwana Katende, Gerald Kevin Oluka, Jackson Sembera, Claire Baine, Geoffrey Odoch, Peter Ejou, Laban Kato, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu, Jennifer Serwanga, Christine Hermilia Akoli, Angela Namuyanja, Solomon Opio, Arthur Watelo Kalyebi, Ivan Ssali, Ben Gombe, Susan Mugaba, Hellen Nantambi
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionThis study aimed to delineate longitudinal antibody responses to the Pfizer-BioNTech BNT162b2 COVID-19 vaccine within the Ugandan subset of the Sub-Saharan African (SSA) demographic, filling a significant gap in global datasets.MethodsWe
Externí odkaz: https://doaj.org/article/749743b1ec32400191b68e3c3266412d
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3
Akademický článek
Sustained S-IgG and S-IgA antibodies to Moderna’s mRNA-1273 vaccine in a Sub-Saharan African cohort suggests need for booster timing reconsiderations
Autor: Jennifer Serwanga, Violet Ankunda, Joseph Ssebwana Katende, Claire Baine, Gerald Kevin Oluka, Geoffrey Odoch, Hellen Nantambi, Susan Mugaba, Angella Namuyanja, Ivan Ssali, Peter Ejou, Laban Kato, The COVID-19 Immunoprofiling Team, Monica Musenero, Pontiano Kaleebu, Jackson Sembera, Betty Oliver Auma, Solomon Opio, Ben Gombe
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
IntroductionThis study sought to elucidate the long-term antibody responses to the Moderna mRNA-1273 COVID-19 vaccine within a Ugandan cohort, aiming to contribute to the sparse data on m-RNA vaccine immunogenicity in Sub-Saharan Africa.MethodsWe tra
Externí odkaz: https://doaj.org/article/4193f652b87f48fe898580c284e37647
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4
Akademický článek
Sustained spike-specific IgG antibodies following CoronaVac (Sinovac) vaccination in sub-Saharan Africa, but increased breakthrough infections in baseline spike-naive individuals
Autor: Jackson Sembera, Claire Baine, Violet Ankunda, Joseph Ssebwana Katende, Gerald Kevin Oluka, Christine Hermilia Akoli, Laban Kato, Geoffrey Odoch, Peter Ejou, Solomon Opio, Monica Musenero, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu, Jennifer Serwanga
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionThis study investigated the antibody responses to the inactivated COVID-19 vaccine, CoronaVac (Sinovac Biotech) in the African population to provide valuable insights into long-term immunity and breakthrough infections against SARS-CoV-2
Externí odkaz: https://doaj.org/article/fd22ad6deacf4d7ba908cf15ff6472fc
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5
Akademický článek
Seroprevalence and durability of antibody responses to AstraZeneca vaccination in Ugandans with prior mild or asymptomatic COVID-19: implications for vaccine policy
Autor: Jennifer Serwanga, Claire Baine, Susan Mugaba, Violet Ankunda, Betty Oliver Auma, Gerald Kevin Oluka, Laban Kato, Isaac Kitabye, Jackson Sembera, Geoffrey Odoch, Peter Ejou, Amina Nalumansi, Ben Gombe, Monica Musenero, Pontiano Kaleebu, the COVID-19 Immunoprofiling Team, Christine Hermilia Akoli, Deus Mwesigwa, Ivan Ssali, Hellen Nantambi, Angela Namuyanja, Solomon Opio, Arthur Watelo Kalyebi, Joseph Ssebwana Katende
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionThe duration and timing of immunity conferred by COVID-19 vaccination in sub-Saharan Africa are crucial for guiding pandemic policy interventions, but systematic data for this region is scarce. This study investigated the antibody respons
Externí odkaz: https://doaj.org/article/12ba7b1e3b934d3ea067f47b5d80e727
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6
Akademický článek
Pre-pandemic SARS-CoV-2-specific IFN-γ and antibody responses were low in Ugandan samples and significantly reduced in HIV-positive specimens
Autor: Hellen Nantambi, Jackson Sembera, Violet Ankunda, Ivan Ssali, Arthur Watelo Kalyebi, Gerald Kevin Oluka, Laban Kato, Bahemuka Ubaldo, Freddie Kibengo, Joseph Ssebwana Katende, Ben Gombe, Claire Baine, Geoffrey Odoch, Susan Mugaba, Obondo James Sande, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu, Jennifer Serwanga
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionWe investigated whether prior SARS-CoV-2-specific IFN-γ and antibody responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low disease severity.MethodsWe used nucleoprotein (N), spike (S), NTD, RBD, envelope,
Externí odkaz: https://doaj.org/article/546f6a4b64e04285a89374a02f81b4d1
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8
Akademický článek
Optimisation and Validation of a conventional ELISA and cut-offs for detecting and quantifying anti-SARS-CoV-2 Spike, RBD, and Nucleoprotein IgG, IgM, and IgA antibodies in Uganda
Autor: Gerald Kevin Oluka, Patricia Namubiru, Laban Kato, Violet Ankunda, Ben Gombe, Matthew Cotten, The COVID-19 Immunoprofiling Team, Monica Musenero, Pontiano Kaleebu, Julie Fox, Jennifer Serwanga, Claire Baine, Jackson Sembera, Susan Mugaba, Christine Hermilia Akoli, Geoffrey Odoch, Deus Mwesigwa, Peter Ejou, Joseph Ssebwana Katende
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
There is an urgent need for better immunoassays to measure antibody responses as part of immune-surveillance activities and to profile immunological responses to emerging SARS-CoV-2 variants. We optimised and validated an in-house conventional ELISA
Externí odkaz: https://doaj.org/article/eade7db238e74c73973a178e6839d878
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9
Akademický článek
Persistent and robust antibody responses to ChAdOx1-S Oxford-AstraZeneca (ChAdOx1-S, Covishield) SARS-CoV-2 vaccine observed in Ugandans across varied baseline immune profiles.
Autor: Jennifer Serwanga, Gerald Kevin Oluka, Claire Baine, Violet Ankunda, Jackson Sembera, Laban Kato, Joseph Ssebwana Katende, Geoffrey Odoch, Betty Oliver Auma, Ben Gombe, COVID-19 Immunoprofiling Team, Monica Musenero, Pontiano Kaleebu
Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0303113 (2024)
Understanding SARS-CoV-2 vaccine-induced antibody responses in varied antigenic and serological prior exposures can guide optimal vaccination strategies for enhanced immunogenicity. We evaluated spike (S)-directed IgG, IgM, and IgA antibody optical d
Externí odkaz: https://doaj.org/article/97ffa7599c1441e4807481d7a29eb2bb
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10
Akademický článek
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