Zobrazeno 1 - 10
of 3 348
pro vyhledávání: '"the Alzheimer's disease Neuroimaging Initiative"'
Autor:
Xiao-jun Jing, Zhi-yuan Zan, Xin Zhou, Yong-lan Xiong, Shu-jiang Ren, Hua Zhang, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Annals of Geriatric Medicine and Research, Vol 28, Iss 3, Pp 273-283 (2024)
Background Advances in blood biomarker discovery have enabled the improved diagnosis and prognosis of Alzheimer's disease (AD). Most branched-chain amino acids, except isoleucine (Ile), are correlated with both mild cognitive impairment (MCI) and AD.
Externí odkaz:
https://doaj.org/article/c4411d928933473db874d44edf282465
Autor:
Maria Ly, Gary Yu, Sang Joon Son, Tharick Pascoal, Helmet T. Karim, the Alzheimer’s disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionBrain age is a machine learning-derived estimate that captures lower brain volume. Previous studies have found that brain age is significantly higher in mild cognitive impairment and Alzheimer’s disease (AD) compared to healthy controls
Externí odkaz:
https://doaj.org/article/0666e007dc07440d98ccfdb725de8e77
Autor:
Tao-Ran Li, Bai-Le Li, Xin-Ran Xu, Jin Zhong, Tai-Shan Wang, Feng-Qi Liu, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundThe relationship between white matter hyperintensities (WMH) and the core features of Alzheimer’s disease (AD) remains controversial. Further, due to the prevalence of co-pathologies, the precise role of WMH in cognition and neurodegenera
Externí odkaz:
https://doaj.org/article/0b585721d2874dd2be2204c870793c39
Autor:
Rebecca L. Winfree, Emma Nolan, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Katherine A. Gifford, Kimberly R. Pechman, Mabel Seto, Vladislav A. Petyuk, Yanling Wang, Julie Schneider, David A. Bennett, Angela L. Jefferson, Timothy J. Hohman, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Recent evidence suggests that Alzheimer’s disease (AD) genetic risk variants (rs1582763 and rs6591561) of the MS4A locus are genome-wide significant regulators of soluble TREM2 levels such that the minor allele of the protective variant (r
Externí odkaz:
https://doaj.org/article/7f931778e48b4a1db9dee9d86d867c84
Autor:
Cecilia Boccalini, Silvia Paola Caminiti, Arturo Chiti, Giovanni B. Frisoni, Valentina Garibotto, Daniela Perani, the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 5, Pp 1236-1249 (2024)
Abstract Objectives Mild cognitive impairment presenting with an amnestic syndrome (aMCI) and amyloid positivity is considered due to AD. Many subjects, however, can show an overall very slow progression relevant for differential diagnosis, prognosis
Externí odkaz:
https://doaj.org/article/6937f1e22c344bb5b1a4f89ef8317a0a
Autor:
Xubing Hao, Rashmie Abeysinghe, Fengbo Zheng, Paul E. Schulz, The Alzheimer’s Disease Neuroimaging Initiative, Licong Cui
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss S3, Pp 1-12 (2024)
Abstract Background Alzheimer’s Disease (AD) is a devastating disease that destroys memory and other cognitive functions. There has been an increasing research effort to prevent and treat AD. In the US, two major data sharing resources for AD resea
Externí odkaz:
https://doaj.org/article/3e93843e387e4f0db28115495e60a313
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background Joint analysis of multiple phenotypes in studies of biological systems such as Genome-Wide Association Studies is critical to revealing the functional interactions between various traits and genetic variants, but growth of data in
Externí odkaz:
https://doaj.org/article/3142c9768ee44101b434dffee2fcf688
Autor:
Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Kensaku Kasuga, Yuko Saito, Shigeo Murayama, Akiyoshi Kakita, Hiroyasu Akatsu, Kouichi Ozaki, Shumpei Niida, Ryozo Kuwano, Takeshi Iwatsubo, Akihiro Nakaya, Takeshi Ikeuchi, the Alzheimer’s Disease Neuroimaging Initiative, the Japanese Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Polygenic effects have been proposed to account for some disease phenotypes; these effects are calculated as a polygenic risk score (PRS). This score is correlated with Alzheimer’s disease (AD)-related phenotypes, such as biomar
Externí odkaz:
https://doaj.org/article/57b43de8caa148689ec698144a567a93
Autor:
Chao Wang, Rukun Cheng, Wenhao Yang, Lin Qiu, Haifeng Liu, the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Brain and Behavior, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Objective To explore the functional connectivity (FC) characteristics of the episodic memory network (EMN) in amnestic mild cognitive impairment (aMCI) patients with different levels of executive function (EF). Methods This study included 76
Externí odkaz:
https://doaj.org/article/3cd38d7a1a3d4c47b91fc44b1745e386
Autor:
Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Kensaku Kasuga, Yuko Saito, Shigeo Murayama, Akiyoshi Kakita, Hiroyasu Akatsu, Kouichi Ozaki, Shumpei Niida, Ryozo Kuwano, Takeshi Iwatsubo, Akihiro Nakaya, Takeshi Ikeuchi, the Alzheimer’s Disease Neuroimaging Initiative, the Japanese Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/a23cc4e69d214992ac7e7d84d5eb743e