Zobrazeno 1 - 10
of 213
pro vyhledávání: '"thbs2"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2251-2266 (2024)
Background: Acting as mediators in cell-matrix and cell-cell communication, matricellular proteins play a crucial role in cancer progression. Thrombospondins (TSPs), a type of matricellular glycoproteins, are key regulators in cancer biology with mul
Externí odkaz:
https://doaj.org/article/ac8a0eb6caec48e38248e4087cd707cc
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34630- (2024)
Background: Breast cancer is a highly malignant disease worldwide, but there are currently no sufficient molecular biomarkers to predict patient prognosis and guide radiotherapy. The tumor microenvironment (TME) is an important factor affecting tumor
Externí odkaz:
https://doaj.org/article/ecc34a30fa5c4b7b89c9a7b258e54126
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background THBS2, a member of the extracellular matrix glycoprotein family, can effectively inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role of THBS2 in various types of cancers and the mechanisms u
Externí odkaz:
https://doaj.org/article/603349a1a80a4e638cc6aa7029b1ddfe
Autor:
Cuihua Qi, Huiying Shi, Mengke Fan, Weigang Chen, Hailing Yao, Chen Jiang, Lingjun Meng, Suya Pang, Rong Lin
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Our previous study found that bone marrow-derived mesenchymal stem cells (BMSCs) promote Helicobacter pylori (H pylori)-associated gastric cancer (GC) progression by secreting thrombospondin-2 (THBS2). Extracellular vesicles (EVs)
Externí odkaz:
https://doaj.org/article/b57d3a7f71bb4675ab815d42951ab499
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible lung disease characterized by pulmonary fibrosis and lung dysfunction, ultimately leading to respiratory failure. Many preclinical studies have invest
Externí odkaz:
https://doaj.org/article/c73d06e5f9d246c99ad570c9878253a0
Autor:
Jianxiong Li, Huaguo Liang, Wentao Xiao, Peng Wei, Hongmei Chen, Zexin Chen, Ruihui Yang, Huan Jiang, Yongli Zhang
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Ovarian cancer is one of the most lethal cancers in women because it is often diagnosed at an advanced stage. The molecular markers investigated thus far have been unsatisfactory. Methods We performed whole-exome sequencing on the
Externí odkaz:
https://doaj.org/article/6239f1ab428e4d3ea1511fa8776adc2e
Autor:
Haytham Ali, Manar AbdelMageed, Lina Olsson, Gudrun Lindmark, Marie-Louise Hammarström, Sten Hammarström, Basel Sitohy
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionApproximately 25% of colon cancer (CC) patients having curative surgery will relapse. Therefore, it is crucial to identify patients with increased recurrence risk to offer them adjuvant chemotherapy. Three markers with prominent expressio
Externí odkaz:
https://doaj.org/article/56d4ebe012504fed8377f8f5dc7c7687
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 38, Iss 5, Pp 469-478 (2022)
Abstract Colorectal cancer (CRC) is the most common human digestive malignancy with a poor prognosis; the pathophysiology of colon cancer involves multiple linkages of regulatory networks. Recently, thrombospondin 2 (THBS2) has been extensively studi
Externí odkaz:
https://doaj.org/article/d64ca0c4ee0d4e7dbd46c41abea974be
Autor:
Zheng Yang, Hongfang Wu, Kai Zhang, Shilei Rao, Shuran Qi, Manxiang Liu, Ying Chen, Yang Wang
Publikováno v:
Thoracic Cancer, Vol 13, Iss 5, Pp 678-689 (2022)
Abstract Background Radioresistance is a common cause of treatment failure in many cancers, including non‐small cell lung cancer (NSCLC). Circular RNA (circRNA) has been shown to be involved in the radiosensitivity of many cancers. However, the rol
Externí odkaz:
https://doaj.org/article/e54114b9590141dd9ae4e7b6809052bb