Zobrazeno 1 - 10
of 258
pro vyhledávání: '"tgf—transforming growth factor"'
Autor:
Samuel James Brake, Wenying Lu, Collin Chia, Greg Haug, Josie Larby, Ashutosh Hardikar, Gurpreet K. Singhera, Tillie L. Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCOPD is a common disease characterized by respiratory airflow obstruction. TGF-β1 and SMAD pathway is believed to play a role in COPD pathogenesis by driving epithelial mesenchymal transition (EMT).MethodsWe investigated TGF-β1 signalling
Externí odkaz:
https://doaj.org/article/1785ac62c9de46619da72af6e7aa262d
Autor:
Sirisha Vammi, Jaya Lakshmi Bukyya, Anulekha Avinash CK, M. L. Avinash Tejasvi, Archana Pokala, Chanchala HP, Priyanka Talwade, Praveen Kumar Neela, T. K. Shyamilee, Mary Oshin, Veenila Pantala
Publikováno v:
Global Medical Genetics, Vol 08, Iss 02, Pp 041-050 (2021)
Bone is a specialized form of connective tissue, which is mineralized and made up of approximately 28% type I collagen and 5% noncollagenous matrix proteins. The properties of bone are very remarkable, because it is a dynamic tissue, undergoing const
Externí odkaz:
https://doaj.org/article/78aa2de362fc4971a60606b21c060be6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionTGF-β and its receptors play a crucial role in asthma pathogenesis and bronchial remodeling in the course of the disease. TGF-β1, TGF-β2, and TGF-β3 isoforms are responsible for chronic inflammation, bronchial hyperreactivity, myofibr
Externí odkaz:
https://doaj.org/article/fa54ec33dc054f0b816f26e993509b89
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Artemisinin is an anti-inflammatory phytomedicine with broad-spectrum antiviral activity. Artemisinin and its antimalarial properties were discovered by the Chinese scientist Tu Youyu, who became one of the laureates of the 2015 Nobel Prize in Physio
Externí odkaz:
https://doaj.org/article/2edafb1073a142b2bcdb33e435f792bb
Autor:
Somayeh Saadat, Mahdi Noureddini, Maryam Mahjoubin-Tehran, Sina Nazemi, Layla Shojaie, Michael Aschner, Behnaz Maleki, Mohammad Abbasi-kolli, Hasan Rajabi Moghadam, Behrang Alani, Hamed Mirzaei
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions, known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the heart muscle. Transforming growth factor β (TGF-β) as a pivotal cyt
Externí odkaz:
https://doaj.org/article/518fd9fb6bda4710bbf170fb24642cf1
Autor:
Melanie A. Kimm, Vanessa Franziska Schmidt, Max L.A. Ebert, Lena Pfaff, Anne von Thaden, Moritz Wildgruber
Publikováno v:
JACC: Basic to Translational Science
Central Illustration
Highlights • Neointimal hyperplasia is the major factor contributing to restenosis after angioplasty procedures. • Multiple animal models exist to study basic and translational aspects of restenosis formation. • Animal
Highlights • Neointimal hyperplasia is the major factor contributing to restenosis after angioplasty procedures. • Multiple animal models exist to study basic and translational aspects of restenosis formation. • Animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88165634a122d3faf899cdcac81ed099
https://doi.org/10.1016/j.jacbts.2021.06.006
https://doi.org/10.1016/j.jacbts.2021.06.006
Autor:
Janarthanan Sathananthan, Devyn Zaminski, Stephanie L. Sellers, Gaurav S. Gulsin, Rihab Bouchareb, Azeem Latib, Rong Bing, Philippe Pibarot
Publikováno v:
JACC: Basic to Translational Science
Highlights • Activated platelets are associated with AS. • Platelets are a player in bioprosthetic valve dysfunction. • Randomized trials have assessed clinical outcomes with various antiplatelet/anticoagulation strategies in patients undergoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49d6ebbebf0b817edc101a06595b4e7
http://europepmc.org/articles/PMC8733745
http://europepmc.org/articles/PMC8733745
Autor:
Bulat A. Ziganshin, Maryann Tranquilli, Osama Anis, Gary S. Kopf, Richard S. Sieller, Mohammad A. Zafar, John A. Elefteriades
Publikováno v:
JACC Case Reports
Three patients developed severe ascending aortic aneurysm requiring surgical resection after heart transplantation. In all 3 cases, the donor aorta of the transplant remained normal in caliber, despite the development of a large aneurysm in the nativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af97b8bae60548b46d6e742f9adbe05b
https://doi.org/10.1016/j.jaccas.2021.07.010
https://doi.org/10.1016/j.jaccas.2021.07.010
Autor:
Steven G. Wise, David A. Robinson, Yuen Ting Lam, Isabelle Ryder, Martin K.C. Ng, Miguel Santos, Richard P. Tan, Nianji Yang, Praveesuda L. Michael
Publikováno v:
JACC: Basic to Translational Science
Highlights • Revascularization for PAD has been characterized by the adaptation of technologies from the treatment of CAD, with few therapies specifically developed for PAD. • In light of recent increases in all-cause mortality driven by endovasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e4ee4b9cd9a162099cb42e89723720
https://doi.org/10.1016/j.jacbts.2021.04.008
https://doi.org/10.1016/j.jacbts.2021.04.008
Autor:
Shinichiro Ono, Kyoichiro Maekawa, Kengo Kanetaka, Mampei Yamashita, Tamotsu Kuroki, Masaaki Hidaka, Toshiyuki Adachi, Naomi Matsumura, Susumu Eguchi, Tomohiko Adachi, Yusuke Sakai
Publikováno v:
Regenerative Therapy, Vol 16, Iss, Pp 42-52 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction Intraportal islet transplantation is a promising therapeutic approach for patients with type 1 diabetes mellitus (T1DM). However, despite being minimally invasive, the method has some limitations, such as short-term graft loss, portal ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893c069593595c8b4c866ee01a5eb3c2
http://www.sciencedirect.com/science/article/pii/S2352320420301012
http://www.sciencedirect.com/science/article/pii/S2352320420301012