Zobrazeno 1 - 10
of 93
pro vyhledávání: '"territorial matrix"'
Publikováno v:
European Cells & Materials, Vol 34, Pp 70-82 (2017)
Dramatic alterations in mechanical properties have been documented for osteoarthritic (OA) cartilage. However, the matrix composition underlying these changes has not been mapped and their aetiology is not entirely understood. We hypothesised that an
Externí odkaz:
https://doaj.org/article/7cfd5cb6501040c6b6a1ab063aeae750
Autor:
Katherine Lakstins, David C. Flanigan, Lauren Arnold, Gunjan Agarwal, Gilian Gunsch, Devina Purmessur, Nikhit Gadde, Safdar N. Khan, Blain Jones
Publikováno v:
Journal of Orthopaedic Research. 39:1898-1907
Given the importance of the cartilage endplate (CEP) in low back pain (LBP), there is a need to characterize the human CEP at the molecular, cell, and tissue levels to inform treatment strategies that target it. The goal of this study was to characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147f2bd2a243a7376c502f61f4f94d2d
https://doi.org/10.1002/jor.24854
https://doi.org/10.1002/jor.24854
Autor:
Christian Brenneis, Donata Harazin, Didier Merciris, Anne Gigout, Sven Lindemann, Ahuva Nissim, Louise M. Topping
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-11 (2021)
Background Osteoarthritis (OA) is a disease of the whole joint, with articular cartilage breakdown as a major characteristic. Inflammatory mediators, proteases, and oxidants produced by chondrocytes are known to be responsible for driving cartilage d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf13e4bdcf95b9146c2b704b89f50e7a
http://europepmc.org/articles/PMC8045329
http://europepmc.org/articles/PMC8045329
Publikováno v:
Journal of the mechanical behavior of biomedical materials. 112
From previous investigations it has been shown that there exists healthy-appearing articular cartilage that contains collagen fibril network destructuring. It is hypothesised that such sub-micron scale destructuring not only presents an increased vul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24494f09977682d1c92e12fff3066e54
https://pubmed.ncbi.nlm.nih.gov/32861062
https://pubmed.ncbi.nlm.nih.gov/32861062
Publikováno v:
Matrix Biology, 71-72, 40-50
Osteoarthritis is a painful joint disease characterized by progressive degeneration of the articular cartilage as well as associated changes to the subchondral bone, synovium, and surrounding joint tissues. While the effects of osteoarthritis on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe664d432aebabba3e477b67a864a23
https://doi.org/10.1016/j.matbio.2018.05.008
https://doi.org/10.1016/j.matbio.2018.05.008
Publikováno v:
European Cells & Materials, Vol 34, Pp 70-82 (2017)
Dramatic alterations in mechanical properties have been documented for osteoarthritic (OA) cartilage. However, the matrix composition underlying these changes has not been mapped and their aetiology is not entirely understood. We hypothesised that an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81429b2a999ed4e4fe5344ced620ac83
https://doi.org/10.22203/ecm.v034a05
https://doi.org/10.22203/ecm.v034a05
Autor:
Jessica C. Mansfield, C. Peter Winlove
Publikováno v:
Journal of Anatomy
The distribution and composition of endogenous lipids in articular cartilage and transport of exogenous fatty acids have been investigated on a microscopic scale in fresh bovine articular cartilage. To investigate the distribution and composition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984642f1a3fa472eb96d8b28a0033975
https://doi.org/10.1111/joa.12624
https://doi.org/10.1111/joa.12624
Autor:
Giovanni Grasselli, David M. L. Cooper, Robert S. Liddell, Kushagra Parolia, Birol Ay, John E. Davies, Yusheng Qiu
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Uncontrolled diabetes is associated with increased risk of bony fractures. However, the mechanisms have yet to be understood. Using high-resolution synchrotron micro-CT, we calculated the changes in the microstructure of femoral cortices of streptozo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e08b6643659b31426fbdb934d813a0
https://pubmed.ncbi.nlm.nih.gov/31925331
https://pubmed.ncbi.nlm.nih.gov/31925331
Autor:
Nicola J. Kuiper, Rebecca L Davies
Publikováno v:
Bioengineering, 6(1):22
Bioengineering, Vol 6, Iss 1, p 22 (2019)
Bioengineering
Bioengineering, Vol 6, Iss 1, p 22 (2019)
Bioengineering
Articular cartilage is composed of chondrons within a territorial matrix surrounded by a highly organized extracellular matrix comprising collagen II fibrils, proteoglycans, glycosaminoglycans, and non-collagenous proteins. Damaged articular cartilag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87720208748edad55c6ff90fabc8fb9d
Autor:
Liqin Zheng, Huang Xinpeng, Jiyang Dong, Xiaoqin Zhu, Jianxin Chen, Shuangmu Zhuo, Hong Lihong, Jianfeng Wu
Publikováno v:
IEEE Photonics Journal, Vol 8, Iss 3, Pp 1-10 (2016)
Cartilage is one of the most important tissues in mammalian growth and is classified into three types: hyaline, fibro, and elastic. To illustrate its potential as a clinical diagnostic tool, nonlinear optical microscopy (NLOM) was applied to simultan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144636ef2c043e11d760c537bd756755
https://ieeexplore.ieee.org/document/7457199/
https://ieeexplore.ieee.org/document/7457199/