Macitentan in Pulmonary Arterial Hypertension Due to Congenital Heart Disease (CHD-PAH): Real-World Evidence from the OPUS/OrPHeUS Studies.

Autor: Chin, Kelly M.¹ (AUTHOR) kelly.chin@utsouthwestern.edu, Channick, Richard² (AUTHOR), Kim, Nick H.³ (AUTHOR), Ong, Rose⁴ (AUTHOR), Turricchia, Stefano⁵ (AUTHOR), Martin, Nicolas⁶ (AUTHOR), Mitchell, Lada⁶ (AUTHOR), McLaughlin, Vallerie V.⁷ (AUTHOR)

Publikováno v: Cardiology & Therapy. Dec2024, Vol. 13 Issue 4, p775-796. 22p.

Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy.

Autor: Lahrouchi N; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Postma AV; Department of Clinical Genetics, and.; Department of Medical Biology, Amsterdam UMC, Amsterdam, Netherlands., Salazar CM; Department of Pharmacological Sciences and Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, USA., De Laughter DM; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Tjong F; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Piherová L; Research Unit for Rare Diseases, Department of Pediatrics and Adolescent Medicine, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Bowling FZ; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA., Zimmerman D; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Lodder EM; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Ta-Shma A; Department of Pediatric Cardiology, Hadassah, Hebrew University Medical Center, Jerusalem, Israel., Perles Z; Department of Pediatric Cardiology, Hadassah, Hebrew University Medical Center, Jerusalem, Israel., Beekman L; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Ilgun A; Department of Medical Biology, Amsterdam UMC, Amsterdam, Netherlands., Gunst Q; Department of Medical Biology, Amsterdam UMC, Amsterdam, Netherlands., Hababa M; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Škorić-Milosavljević D; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Stránecký V; Research Unit for Rare Diseases, Department of Pediatrics and Adolescent Medicine, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Tomek V; Children's Heart Centre, 2nd Faculty of Medicine, Charles University in Prague, Motol University Hospital, Prague, Czech Republic., de Knijff P; Department of Human Genetics, Leiden University Medical Centre, Leiden, Netherlands., de Leeuw R; Department of Human Genetics, Leiden University Medical Centre, Leiden, Netherlands., Robinson JY; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Burn SC; Department of Obstetrics, Gynecology and Women's Health., Mustafa H; Department of Obstetrics, Gynecology and Women's Health., Ambrose M; Department of Pediatrics, Division of Pediatric Cardiology, and., Moss T; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA., Jacober J; Department of Pediatrics, Ochsner Clinic, Tulane University, University of Queensland, New Orleans, Louisiana, USA., Niyazov DM; Department of Pediatrics, Ochsner Clinic, Tulane University, University of Queensland, New Orleans, Louisiana, USA., Wolf B; Division of Genetics, Birth Defects and Metabolic Disorders, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Kim KH; Division of Genetics, Birth Defects and Metabolic Disorders, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Cherny S; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Division of Cardiology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA., Rousounides A; Makarios Medical Centre, Nicosia, Cyprus., Aristidou-Kallika A; Ultrasound and Fetal Medicine Diagnostic Centre, Nicosia, Cyprus., Tanteles G; Cyprus School of Molecular Medicine, Nicosia, Cyprus.; Department of Clinical Genetics, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus., Ange-Line B; UMR 1231 INSERM, GAD, Université Bourgogne Franche-Comté, Dijon, France.; Unité Fonctionnelle d'Innovation en Diagnostique Génomique des Maladies Rares, FHU-TRANSLAD, Centre Hospitalier Universitaire Estaing (CHU), Dijon Bourgogne, Dijon, France., Denommé-Pichon AS; UMR 1231 INSERM, GAD, Université Bourgogne Franche-Comté, Dijon, France.; Unité Fonctionnelle d'Innovation en Diagnostique Génomique des Maladies Rares, FHU-TRANSLAD, Centre Hospitalier Universitaire Estaing (CHU), Dijon Bourgogne, Dijon, France., Francannet C; Service de Génétique Médicale, CHU Estaing, Clermont-Ferrand, France., Ortiz D; Medical Genetics Department, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA., Haak MC; Department of Obstetrics and., Ten Harkel AD; Department of Pediatric Cardiology, Leiden University Medical Centre, Leiden, Netherlands., Manten GT; Department of Obstetrics and., Dutman AC; Department of Pathology, Isala Women and Children's Hospital, Zwolle, Netherlands., Bouman K; University Medical Center Groningen, Department of Genetics, University of Groningen, Groningen, Netherlands., Magliozzi M; Genetic and Rare Disease Research Division, Bambino Gesù Children's Hospital IRCCS, Rome, Italy., Radio FC; Genetic and Rare Disease Research Division, Bambino Gesù Children's Hospital IRCCS, Rome, Italy., Santen GW; Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands., Herkert JC; University Medical Center Groningen, Department of Genetics, University of Groningen, Groningen, Netherlands., Brown HA; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Elpeleg O; Department of Genetics, Hadassah, Hebrew University Medical Center, Jerusalem, Israel., van den Hoff MJ; Department of Medical Biology, Amsterdam UMC, Amsterdam, Netherlands., Mulder B; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences., Airola MV; Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York, USA., Kmoch S; Research Unit for Rare Diseases, Department of Pediatrics and Adolescent Medicine, 1st Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Barnett JV; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Clur SA; Department of Pediatric Cardiology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands., Frohman MA; Department of Pharmacological Sciences and Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York, USA., Bezzina CR; Amsterdam UMC, University of Amsterdam, Heart Center, Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Mar 01; Vol. 131 (5).

Predictive Role of Atrial Strain, Aortic Stiffness, and Muscle-Related Factors for Maximal and Submaximal Exercise Capacity in Fontan Patients.

Autor: Tekerlek H; Department of Cardiopulmonary Physiotherapy and Rehabilitation, Faculty of Health Sciences, Karamanoglu Mehmetbey University, Karaman, Turkey. haluktekerlek@gmail.com., Aykan HH; Department of Pediatric Cardiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.; Life Support Center, Hacettepe University, Ankara, Turkey., Vardar-Yagli N; Department of Cardiorespiratory Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey., Selcuk SN; Department of Pediatric Cardiology, Ankara Etlik City Hospital, Ankara, Turkey., Basol-Goksuluk M; Department of Biostatistics, Faculty of Medicine, Erciyes University, Kayseri, Turkey., Karagoz T; Department of Pediatric Cardiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey., Saglam M; Department of Cardiorespiratory Rehabilitation, Faculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.

Publikováno v: Pediatric cardiology [Pediatr Cardiol] 2024 Oct 29. Date of Electronic Publication: 2024 Oct 29.

A rare association of the absence of left pulmonary artery with ventricular septal defect, pulmonary hypertension, and more interestingly, patent ductus arteriosus in an adult patient: Case report and literature review.

Autor: Parsaee, Mozhgan¹ (AUTHOR), Saedi, Sedigheh² (AUTHOR), Behrooj, Soudabeh¹ (AUTHOR), Emami, Elaheh¹ (AUTHOR), Salehi, Pegah¹ (AUTHOR) p.salehi345711@gmail.com, Mohammadzadeh, Ali² (AUTHOR)

Publikováno v: Clinical Case Reports. Jul2024, Vol. 12 Issue 7, p1-5. 5p.

Treating Lows: Management of Orthostatic Hypotension.

Autor: Kulkarni S; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Department of Clinical Pharmacology and Therapeutics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Jenkins D; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Lewisham and Greenwich NHS Foundation Trust, London, United Kingdom; and., Dhar A; University of Mississippi Medical Center, Jackson, Mississippi, United States of America., Mir F; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Department of Clinical Pharmacology and Therapeutics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

Publikováno v: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2024 Sep 01; Vol. 84 (3), pp. 303-315. Date of Electronic Publication: 2024 Sep 01.