Zobrazeno 1 - 10
of 1 637
pro vyhledávání: '"ten Dijke P"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Metastasis is the leading cause of cancer-related deaths. Transforming growth factor beta (TGF-β) signaling drives metastasis and is strongly enhanced during cancer progression. Yet, the use of on-target TGF-β signaling inhibitors in the t
Externí odkaz:
https://doaj.org/article/9bb0f02efb034e0c9c89d7c9a48e9cec
Autor:
Yang Hao, Sen Ma, Zili Gu, Alireza Haghparast, Timo Schomann, Zhenfeng Yu, Yuanyuan He, Xiaoxv Dong, Luis J Cruz, Peter ten Dijke
Publikováno v:
Cancer Communications, Vol 43, Iss 4, Pp 513-518 (2023)
Externí odkaz:
https://doaj.org/article/e4d22267e14c4c74a9cf19bb458b1e6c
Autor:
van Ommen Gert Jan B, den Dunnen Johan T, de Gorter David JJ, Terlouw Samuel, van Heiningen Sandra H, Hoogaars Willem MH, Kemaladewi Dwi U, Aartsma-Rus Annemieke, ten Dijke Peter, 't Hoen Peter AC
Publikováno v:
BMC Medical Genomics, Vol 4, Iss 1, p 36 (2011)
Abstract Background Myostatin is a potent muscle growth inhibitor that belongs to the Transforming Growth Factor-β (TGF-β) family. Mutations leading to non functional myostatin have been associated with hypermuscularity in several organisms. By con
Externí odkaz:
https://doaj.org/article/07a8f75a00944b1382c2e811e51b786e
Autor:
Lonneke Rotteveel, Alex J. Poot, Esther J. M. Kooijman, Robert C. Schuit, Ingrid Schalij, Xiaoqing Sun, Kondababu Kurakula, Chris Happé, Wissam Beaino, Peter ten Dijke, Adriaan A. Lammertsma, Harm Jan Bogaard, Albert D. Windhorst
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Transforming growth factor β (TGFβ) activity is perturbed in remodelled pulmonary vasculature of patients with pulmonary arterial hypertension (PAH), cancer, vascular diseases and developmental disorders. Inhibition of TGFβ, which signals
Externí odkaz:
https://doaj.org/article/d4e5834623554ec79cfeb8672ef8eb29
Publikováno v:
BMC Cell Biology, Vol 8, Iss 1, p 41 (2007)
Abstract Background Bone morphogenetic proteins (BMPs) are members of the TGF-beta superfamily and were originally identified as proteins that induce ectopic bone formation. BMPs were shown subsequently to be involved in several biological processes
Externí odkaz:
https://doaj.org/article/bfcb407fa4be494e8d37cf289060a436
Publikováno v:
MedComm, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Immune checkpoint inhibitors (ICIs) have shown remarkable success in cancer treatment. However, in cancer patients without sufficient antitumor immunity, numerous data indicate that blocking the negative signals elicited by immune checkpoint
Externí odkaz:
https://doaj.org/article/b2492f23f9e647fd80df24463a55f385
Autor:
Feng Xie, Xiaoxue Zhou, Peng Su, Heyu Li, Yifei Tu, Jinjin Du, Chen Pan, Xiang Wei, Min Zheng, Ke Jin, Liyan Miao, Chao Wang, Xuli Meng, Hans van Dam, Peter ten Dijke, Long Zhang, Fangfang Zhou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Understanding the factors that hamper immune therapy in breast cancer may increase the range of patients who benefit. Here authors show that breast cancer cells produce and subsequently transfer active TGF-β type II receptors to CD8 + T cells to ren
Externí odkaz:
https://doaj.org/article/38ffd7d9ac664b15a78b87301f59ec04
Akademický článek
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Autor:
Inderson, A., van Hooft, J.E., Micke, P., Johansen, J.S., van Wezel, T., Crobach, S., Baart, V.M., Quist, B.S., Roet, J.E.G., Kop, M.E., Harryvan, T.J., Hawinkels, L.J.A.C., Östman, A., ten Dijke, P., Strell, C., Hornsveld, M.
Publikováno v:
In Gastro Hep Advances 2022 1(4):678-681
Autor:
Dieuwke L. Marvin, Jelmer Dijkstra, Rabia M. Zulfiqar, Michiel Vermeulen, Peter ten Dijke, Laila Ritsma
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8676 (2023)
Despite advances in treatment for metastatic melanoma patients, patients with liver metastasis have an unfavorable prognosis. A better understanding of the development of liver metastasis is needed. The multifunctional cytokine Transforming Growth Fa
Externí odkaz:
https://doaj.org/article/18040f596993496fbe86606be96ee69d