Zobrazeno 1 - 10
of 223
pro vyhledávání: '"telomerase reverse transcriptase (TERT)"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 10, Pp 1436-1441 (2024)
Oxidative stress is the result of imbalance between the formation of reactive oxygen species (ROS) and antioxidant level. Mitochondria are important organelles regulating oxidative stress. Telomerase reverse transcriptase (TERT) not only in the nucle
Externí odkaz:
https://doaj.org/article/15cfdfd4a7f446aaab4b5c903fb45e00
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immunosenescence impacts both the innate and adaptive immune systems, predominantly affecting certain immune cell types. A notable manifestation of immunosenescence is the diminished efficacy of adaptive immunity. The excessive senescence of immune c
Externí odkaz:
https://doaj.org/article/ec485cf3bb8346a68aceb3a0c9577e4f
Autor:
Michiko Matsuse, Norisato Mitsutake
Publikováno v:
Endocrine Journal, Vol 70, Iss 11, Pp 1035-1049 (2023)
TERT promoter mutations (TERT-p mutations) have been found in many types of cancer and have emerged to play critical roles in tumor progression. The mutations upregulate TERT transcription, and TERT not only elongates telomeres and confers unlimited
Externí odkaz:
https://doaj.org/article/3d1d60a7c28941d19f207257e6d5fdbd
Prognostic value and immune landscapes of TERT promoter methylation in triple negative breast cancer
Autor:
Fei Lin, Jiajia Huang, Wancui Zhu, Tongchao Jiang, Jia Guo, Wen Xia, Miao Chen, Ling Guo, Wuguo Deng, Huanxin Lin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTreatment options for patients with triple-negative breast cancer (TNBC) remain limited to mainstay therapies owing to a lack of efficacious therapeutic targets. Accordingly, there is an urgent need to discover and identify novel molecular
Externí odkaz:
https://doaj.org/article/c26b6962b53343aa8f16f7d12d40316a
Akademický článek
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Autor:
Tsung-Jang Yeh, Chi-Wen Luo, Jeng-Shiun Du, Chien-Tzu Huang, Min-Hung Wang, Tzer-Ming Chuang, Yuh-Ching Gau, Shih-Feng Cho, Yi-Chang Liu, Hui-Hua Hsiao, Li-Tzong Chen, Mei-Ren Pan, Hui-Ching Wang, Sin-Hua Moi
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 691 (2023)
Head and neck cancers (HNCs) are among the ten leading malignancies worldwide. Despite significant progress in all therapeutic modalities, predictive biomarkers, and targeted therapies for HNCs are limited and the survival rate is unsatisfactory. The
Externí odkaz:
https://doaj.org/article/4ed27ffb8415412c8bc1882fbbe58848
Autor:
Gh. Rasool Bhat, Amrita Bhat, Sonali Verma, Itty Sethi, Ruchi Shah, Varun Sharma, Khursheed A. Dar, Deepak Abrol, Subiya Kaneez, Sandeep Kaul, Ramesh Ganju, Rakesh Kumar
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Telomere genetics has recently been emerged as an important field in molecular oncology. Various genome-wide association studies in different population groups have revealed that polymorphisms in Telomere maintenance gene (TERT) g
Externí odkaz:
https://doaj.org/article/2a8430d296664832b40167989cefbd89
Autor:
Yanxiu Li, Iokfai Cheang, Zhongwen Zhang, Wenming Yao, Yanli Zhou, Haifeng Zhang, Yun Liu, Xiangrong Zuo, Xinli Li, Quan Cao
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundTelomere length and telomerase are associated in development of cardiovascular diseases. Study aims to investigate the associations of TERC and TERT gene polymorphism and leukocyte telomere length (LTL) in the prognosis of acute heart failu
Externí odkaz:
https://doaj.org/article/8e794b6af68a4348a7d49a979c6ddc98
Akademický článek
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Akademický článek
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