Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase

Autor: Isabella Bolognino, Antonio Carrieri, Rosa Purgatorio, Marco Catto, Rocco Caliandro, Benedetta Carrozzini, Benny Danilo Belviso, Maria Majellaro, Eddy Sotelo, Saverio Cellamare, Cosimo Damiano Altomare

Publikováno v: Separations, Vol 9, Iss 7, p 7 (2022)
Separations 9 (2022). doi:10.3390/separations9010007
info:cnr-pdr/source/autori:Bolognino, Isabella; Carrieri, Antonio; Purgatorio, Rosa; Catto, Marco; Caliandro, Rocco; Carrozzini, Benedetta; Belviso, Benny Danilo; Majellaro, Maria; Sotelo, Eddy; Cellamare, Saverio; Altomare, Cosimo Damiano/titolo:Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase/doi:10.3390%2Fseparations9010007/rivista:Separations/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Separations; Volume 9; Issue 1; Pages: 7

The enantiomeric separation of 15 racemic 4-aryl-3,4-dihydropyrimidin-2(1H)-one (DHP) alkoxycarbonyl esters, some of which proved to be highly active as A2B adenosine receptor antagonists, was carried out by HPLC on ChirobioticTM TAG, a chiral statio

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https://www.mdpi.com/2297-8739/9/1/7

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Three-dimensional structure of cyclic antibiotic teicoplanin aglycone using NMR distance and dihedral angle restraints in a DMSO solvation model

Autor: Shengli Ma, Nina C. Gonnella, Om P. Choudhary, Keith R. Fandrick, Nelu Grinberg, Mark Mcloughlin

Publikováno v: Magnetic Resonance in Chemistry. 53:829-835

The three-dimensional solution conformation of teicoplanin aglycone was determined using NMR spectroscopy. A combination of NOE and dihedral angle restraints in a DMSO solvation model was used to calculate an ensemble of structures having a root mean

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79222f5538e99188a676391800782736
https://doi.org/10.1002/mrc.4279

Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantio separation of racemic amino acids employing composition-constrained eluents

Autor: Matthias Bechtold, Sven Panke, Matthias Heinemann

Publikováno v: Journal of Chromatography A, 1113(1-2), 167-176. ELSEVIER SCIENCE BV

The suitability of a teicoplanin-aglycone based chiral stationary phase for the simulated moving bed (SMB) enantioseparation of amino acids under enzyme-compatible conditions was shown following a procedure that is based solely on model-based simulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bbb710460f475812205fdec22355cb7
https://research.rug.nl/en/publications/ba7e6514-d6cd-4afd-b1f7-8b03b66da71f

Enantioseparation of dipeptides and tripeptides by micro-HPLC comparing teicoplanin and teicoplanin aglycone as chiral selectors

Autor: Maria Hölbling, Martin G. Schmid, Nikola Schnedlitz, Gerald Gübitz

Publikováno v: Journal of Biochemical and Biophysical Methods. 61:1-10

Chiral separation of glycyl- and diastereomeric dipeptides and tripeptides was performed by micro-HPLC using macrocyclic antibiotics as chiral selectors. Teicoplanin was compared with teicoplanin aglycone (TAG) regarding selectivity, efficiency and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c322532c99dc4d400ca197703f16e085
https://doi.org/10.1016/j.jbbm.2004.04.006