A SARS-CoV-2 mini-genome assay based on negative-sense RNA to study replication inhibitors and emerging mutations

Autor: Oade Ms, Dirk Eggink, Colin A. Russell, Vial T, te Velthuis Aj

Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded RNA virus and the causative agent of the Coronavirus disease 2019 (COVID-19) pandemic. Efforts to identify inhibitors of SARS-CoV-2 replication enzymes and better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b8c0789937d1a240dd71a7f28e6c64a
https://doi.org/10.1101/2021.06.28.450211

Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus

Autor: Benjamin E. Nilsson-Payant, Gopal, Yung W, Benjamin R. tenOever, Hollie French, Jurre Y. Siegers, Matthew Hardwick, te Velthuis Aj

Publikováno v: bioRxiv
article-version (status) pre
article-version (number) 2

Infections with respiratory viruses can spread via liquid droplets and aerosols, and cause diseases such as influenza and COVID-19. Face masks and other personal protective equipment (PPE) can act as barriers that prevent the spread of respiratory dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc3ada7b05386958728fe140b7a99a6
https://doi.org/10.1101/2020.11.02.365833

Structure of the RNA-dependent RNA polymerase P2 from the cystovirus φ8.

Autor: Latimer-Smith, Merlyn¹ (AUTHOR), Salgado, Paula S.^2,3 (AUTHOR), Forsyth, Ismay¹ (AUTHOR), Makeyev, Eugene^4,5 (AUTHOR), Poranen, Minna M.⁴ (AUTHOR), Stuart, Dave I.^1,2 (AUTHOR), Grimes, Jonathan M.² (AUTHOR), El Omari, Kamel^1,6 (AUTHOR) kamel.el-omari@diamond.ac.uk

Publikováno v: Scientific Reports. 10/12/2024, Vol. 14 Issue 1, p1-11. 11p.

Zn²⁺-dependent association of cysteine-rich protein with virion orchestrates morphogenesis of rod-shaped viruses.

Autor: Yue, Ning¹ (AUTHOR), Jiang, Zhihao¹ (AUTHOR), Pi, Qinglin¹ (AUTHOR), Yang, Meng¹ (AUTHOR), Gao, Zongyu¹ (AUTHOR), Wang, Xueting¹ (AUTHOR), Zhang, He¹ (AUTHOR), Wu, Fengtong¹ (AUTHOR), Jin, Xuejiao¹ (AUTHOR), Li, Menglin² (AUTHOR), Wang, Ying² (AUTHOR), Zhang, Yongliang¹ (AUTHOR), Li, Dawei¹ (AUTHOR) Dawei.Li@cau.edu.cn

Publikováno v: PLoS Pathogens. 6/17/2024, Vol. 20 Issue 6, p1-22. 22p.

Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.

Autor: Robb NC; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK nicole.robb@physics.ox.ac.uk., Te Velthuis AJ; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK.; Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK., Wieneke R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt am Main, Germany., Tampé R; Institute of Biochemistry, Biocenter, Goethe University Frankfurt, Max-von-Laue-Strasse 9, 60438 Frankfurt am Main, Germany., Cordes T; Molecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands., Fodor E; Molecular Microscopy Research Group, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands ervin.fodor@path.ox.ac.uk., Kapanidis AN; Biological Physics Research Group, Clarendon Laboratory, Department of Physics, University of Oxford, Parks Road, Oxford OX1 3PU, UK kapanidis@physics.ox.ac.uk.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2016 Dec 01; Vol. 44 (21), pp. 10304-10315. Date of Electronic Publication: 2016 Sep 30.