Zobrazeno 1 - 10
of 11 386
pro vyhledávání: '"taxol"'
Autor:
Hulya Karaca, Murat Kaya, Handan Açelya Kapkac, Serkan Levent, Yusuf Ozkay, Secil Deniz Ozan, Jens Nielsen, Anastasia Krivoruchko
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Metabolic engineering enables the sustainable and cost-efficient production of complex chemicals. Efficient production of terpenes in Saccharomyces cerevisiae can be achieved by recruiting an intermediate of the mevalonate pathway
Externí odkaz:
https://doaj.org/article/a295840edbce4ef7bdd81a762e3bc912
Autor:
Olivier Romito, Aude Lemettre, Aurélie Chantôme, Ophélie Champion, Noémie Couty, Lobna Ouldamer, Nadine Hempel, Mohamed Trebak, Caroline Goupille, Marie Potier‐Cartereau
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 1853-1865 (2024)
No data are currently available on the functional role of small conductance Ca2+‐activated K+ channels (SKCa) in ovarian cancer. Here, we characterized the role of SK2 (KCa2.2) in ovarian cancer cell migration and chemosensitivity. Using the select
Externí odkaz:
https://doaj.org/article/9b4055aa053c49139808a9db354ee945
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Taxol serves as an efficient natural anticancer agent with extensive applications in the treatment of diverse malignancies. Although advances in synthetic biology have enabled the de novo synthesis of taxol precursors in various microbial ch
Externí odkaz:
https://doaj.org/article/b57aa68916484135abdcbcba39d5f7f8
Autor:
Maria P. Silva, Luísa T. Ferreira, Natércia F. Brás, Lurdes Torres, Andreia Brandão, Manuela Pinheiro, Marta Cardoso, Adriana Resende, Joana Vieira, Carlos Palmeira, Gabriela Martins, Miguel Silva, Carla Pinto, Ana Peixoto, João Silva, Rui Henrique, Sofia Maia, Helder Maiato, Manuel R. Teixeira, Paula Paulo
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background Prostate cancer (PrCa) is the most frequently diagnosed cancer in men. Variants in known moderate- to high-penetrance genes explain less than 5% of the cases arising at early-onset (
Externí odkaz:
https://doaj.org/article/89556ac24efa46d1a230f329bd5bf87d
Autor:
ZHAO Qianqian, ZHU Jingbo
Publikováno v:
Guangxi Zhiwu, Vol 44, Iss 6, Pp 1042-1051 (2024)
This research aimed to establish an analytical method for the quantification of 10-deacetylbaccatin Ⅲ (10-DAB Ⅲ) and Taxol in Taxus yunnanensis. The method of matrix solid phase dispersion coupled with high performance liquid chromatography (MSPD
Externí odkaz:
https://doaj.org/article/96df2788acf6412c989576fee76957a0
Autor:
Asmaa Gamal, Eman Fikry, Nora Tawfeek, Azza M. El-Shafae, Ashraf S. A. El-Sayed, Maher M. El-Domiaty
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract The biosynthetic potency of Taxol by fungi raises their prospective to be a platform for commercial production of Taxol, nevertheless, the attenuation of its productivity with the fungal storage, is the challenge. Thus, screening for a novel
Externí odkaz:
https://doaj.org/article/21c61d8038084d30a6111f5f260294da
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Akademický článek
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Autor:
Behnaz Nowrouzi, Pablo Torres-Montero, Eduard J. Kerkhoven, José L. Martínez, Leonardo Rios-Solis
Publikováno v:
Metabolic Engineering Communications, Vol 18, Iss , Pp e00229- (2024)
Saccharomyces cerevisiae has been conveniently used to produce Taxol® anticancer drug early precursors. However, the harmful impact of oxidative stress by the first cytochrome P450-reductase enzymes (CYP725A4-POR) of Taxol® pathway has hampered suf
Externí odkaz:
https://doaj.org/article/8b15fb22fd7246e281e56e56c65f6c83