Targeting tumour hypoxia to prevent cancer metastasis:from biology, biosensing and technology to drug development : the METOXIA consortium

Autor: James Meehan, Gerhard Jobst, Jan Alsner, Agnes Görlach, Andreas Weltin, Hilda Mujcic, Hubert Flamm, Maria J. Calzada, Anne Hansen Ree, Jochen Kieninger, Philippe Lambin, Jacques Pouysségur, Brad Wouters, Simon P. Langdon, Carol Ward, Luis del Peso, Peter Ebbesen, Silvia Pastorekova, Ludwig Dubois, Yihai Cao, Gerald Urban, Dean C. Singleton, Manuel O. Landázuri, Heidi Lyng, Morten Busk, Margaret Ashcroft, Ian Kunkler, Roben G. Gieling, Kasper M.A. Rouschop, Claudiu T. Supuran, Dan Cojocari, Kasper Toustrup, Johanna Chiche, Marianne Koritzinsky, Scott K. Parks, Erik O. Pettersen, Kjersti Flatmark, Nathalie M. Mazure, Isabella Moser, Ibtissam Marchiq, Adrian L. Harris, Francesca M. Buffa, Jens Overgaard, Kaye J. Williams, Afshan Ahmed, Syed Haider, Andrea Scozzafava

Publikováno v: Pettersen, E O, Ebbesen, P, Gieling, R G, Williams, K J, Dubois, L, Lambin, P, Ward, C, Meehan, J, Kunkler, I H, Langdon, S P, Ree, A H, Flatmark, K, Lyng, H, Calzada, M J, del Peso, L, Landazuri, M O, Görlach, A, Flamm, H, Kieninger, J, Urban, G, Weltin, A, Singleton, D C, Haider, S, Buffa, F M, Harris, A L, Scozzafava, A, Supuran, C T, Moser, I, Jobst, G, Busk, M, Toustrup, K, Overgaard, J, Alsner, J, Pouyssegur, J, Chiche, J, Mazure, N, Marchiq, I, Parks, S, Ahmed, A, Ashcroft, M, Pastorekova, S, Cao, Y, Rouschop, K M, Wouters, B G, Koritzinsky, M, Mujcic, H & Cojocari, D 2015, ' Targeting tumour hypoxia to prevent cancer metastasis : from biology, biosensing and technology to drug development : the METOXIA consortium ', Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 30, no. 5, pp. 689-721 . https://doi.org/10.3109/14756366.2014.966704
Pettersen, E O, Ebbesen, P, Gieling, R G, Williams, K J, Dubois, L, Lambin, P, Ward, C, Meehan, J, Kunkler, I H, Langdon, S P, Ree, A H, Flatmark, K, Lyng, H, Calzada, M J, Peso, L D, Landazuri, M O, Görlach, A, Flamm, H, Kieninger, J, Urban, G, Weltin, A, Singleton, D C, Haider, S, Buffa, F M, Harris, A L, Scozzafava, A, Supuran, C T, Moser, I, Jobst, G, Busk, M, Toustrup, K, Overgaard, J, Alsner, J, Pouyssegur, J, Chiche, J, Mazure, N, Marchiq, I, Parks, S, Ahmed, A, Ashcroft, M, Pastorekova, S, Cao, Y, Rouschop, K M, Wouters, B G, Koritzinsky, M, Mujcic, H & Cojocari, D 2015, ' Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium ', Journal of Enzyme Inhibition and Medicinal Chemistry, pp. 689-721 . https://doi.org/10.3109/14756366.2014.966704
Journal of Enzyme Inhibition and Medicinal Chemistry, 30(5), 689-721. Routledge/Taylor & Francis Group

The hypoxic areas of solid cancers represent a negative prognostic factor irrespective of which treatment modality is chosen for the patient. Still, after almost 80 years of focus on the problems created by hypoxia in solid tumours, we still largely

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https://vbn.aau.dk/da/publications/5759bf2d-1ecb-4f12-9a44-dc3386a78408

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