Zobrazeno 1 - 10
of 298
pro vyhledávání: '"targeted treatments"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Hepatocellular carcinoma (HCC) is a primary liver malignancy with high mortality rates and poor prognosis. Recent advances in high-throughput sequencing and bioinformatic technologies have greatly enhanced the understanding of the genetic an
Externí odkaz:
https://doaj.org/article/32e161ab2ba34b51ba4a3b302e6e35ee
Autor:
Yuchen Chen, Xue-Jun Song
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 589 (2024)
Diabetic neuropathic pain (DNP) is one of the common and severe late-stage complications of diabetes mellitus, which could greatly influence the patients’ quality of life. Patients with DNP often experience spontaneous pain and evoked pain such as
Externí odkaz:
https://doaj.org/article/eab6a258b0a54619af6b2d8bb4af4a1a
Akademický článek
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Publikováno v:
European Medical Journal, Vol 5, Iss 2, Pp 76-84 (2020)
Early diagnosis and personalised disease management remain serious challenges in the field of haematological malignancies, especially for acute conditions. Additionally, reliable and timely detection of minimal residual disease is the key to improvin
Externí odkaz:
https://doaj.org/article/500dcee116ac4e38ab28e3070262f6ba
Autor:
Anette Hauge, Einar K. Rofstad
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Most tumors develop abnormal fibrotic regions consisting of fibroblasts, immune cells, and a dense extracellular matrix (ECM) immersed in a viscous interstitial fluid, and an abundant fibrotic tumor microenvironment (TME) is associated with
Externí odkaz:
https://doaj.org/article/8a91fd5aceec44b7b22ea72f0457fa4e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3819-3832 (2020)
While high-throughput drug screening offers possibilities to profile phenotypic responses of hundreds of compounds, elucidation of the cell context-specific mechanisms of drug action requires additional analyses. To that end, we developed a computati
Externí odkaz:
https://doaj.org/article/25a61671e8804d9591c69081345c5309
Autor:
Myron Christodoulides
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Neisseria pathogens express a Macrophage Infectivity Potentiator Protein (MIP), which belongs to the FK506 binding protein (FKBP) family of proteins that exhibit peptidyl-prolyl cis/trans isomerase (PPIase) activity. Neisseria MIP proteins are potent
Externí odkaz:
https://doaj.org/article/5340ea231eb84ecfa53edd9319ec7d3e
Akademický článek
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Autor:
Marjorie C. Delahaye, Kaoutar-Insaf Salem, Jeoffrey Pelletier, Michel Aurrand-Lions, Stéphane J. C. Mancini
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
B-cell acute lymphoblastic leukemia (B-ALL) represents the malignant counterpart of bone marrow (BM) differentiating B cells and occurs most frequently in children. While new combinations of chemotherapeutic agents have dramatically improved the prog
Externí odkaz:
https://doaj.org/article/90c726d814ee44fd9f214b6f91d38ddd
Autor:
Burmester, Gerd R, Pope, Janet E
Publikováno v:
In The Lancet 10-16 June 2017 389(10086):2338-2348