Zobrazeno 1 - 10
of 335
pro vyhledávání: '"targeted maximum likelihood estimation"'
Autor:
Ivan Nicholas Nkuhairwe, Tonya Marianne Esterhuizen, Lovemore Nyasha Sigwadhi, Jacques Lukenze Tamuzi, Rhoderick Machekano, Peter S. Nyasulu
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Causal inference from observational studies is an area of interest to researchers, advancing rapidly over the years and with it, the methods for causal effect estimation. Among them, Targeted Maximum Likelihood estimation (TMLE) p
Externí odkaz:
https://doaj.org/article/5fa1a91c01b449dcafd4eb54288fbc40
Autor:
Cristian C. Serrano-Mayorga, Sara Duque, Elsa D. Ibáñez-Prada, Esteban Garcia-Gallo, María P. Rojas Arrieta, Alirio Bastidas, Alejandro Rodríguez, Ignacio Martin-Loeches, Luis F. Reyes
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Cefepime and piperacillin/tazobactam are antimicrobials recommended by IDSA/ATS guidelines for the empirical management of patients admitted to the intensive care unit (ICU) with community-acquired pneumonia (CAP). Concerns have been raised
Externí odkaz:
https://doaj.org/article/70da2d8147a345ddb85242e522214142
Autor:
Adovich S. Rivera, Omar Al-Heeti, Lucia C. Petito, Mathew J. Feinstein, Chad J. Achenbach, Janna Williams, Babafemi Taiwo
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Key points Question Is statin use prior to hospital admission for COVID-19 associated with reducing severe inpatient outcomes? Findings In this observational study using electronic health records from a multi-hospital health system in Chicago, we use
Externí odkaz:
https://doaj.org/article/9fcbd9b911734c4f8870cd82a9f1292a
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Objectives To have confidence in one's interpretation of treatment effects assessed by comparing trial results to external controls, minimizing bias is a critical step. We sought to investigate different methods for causal inference in simul
Externí odkaz:
https://doaj.org/article/d331ea02795446d0964693cb2f479408
Autor:
Bryan T. Mayer, Lily Zhang, Allan C. deCamp, Chenchen Yu, Alicia Sato, Heather Angier, Kelly E. Seaton, Nicole Yates, Julie E. Ledgerwood, Kenneth Mayer, Marina Caskey, Michel Nussenzweig, Kathryn Stephenson, Boris Julg, Dan H. Barouch, Magdalena E. Sobieszczyk, Srilatha Edupuganti, Colleen F. Kelley, M. Juliana McElrath, Huub C. Gelderblom, Michael Pensiero, Adrian McDermott, Lucio Gama, Richard A. Koup, Peter B. Gilbert, Myron S. Cohen, Lawrence Corey, Ollivier Hyrien, Georgia D. Tomaras, Yunda Huang
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 594 (2024)
Monoclonal antibodies are commonly engineered with an introduction of Met428Leu and Asn434Ser, known as the LS mutation, in the fragment crystallizable region to improve pharmacokinetic profiles. The LS mutation delays antibody clearance by enhancing
Externí odkaz:
https://doaj.org/article/34ca5d472d9b40e7a742cd8a83e9c15b
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Akademický článek
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Publikováno v:
BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Approximately one-third of pregnant and postnatal women in Ethiopia experience depression posing a substantial health burden for these women and their families. Although associations between postnatal depression and worse infant h
Externí odkaz:
https://doaj.org/article/5820115d627a49a2a725020ef1d07246
Autor:
Carolin Veit, Ronald Herrera, Gudrun Weinmayr, Jon Genuneit, Doris Windstetter, Christian Vogelberg, Erika von Mutius, Dennis Nowak, Katja Radon, Jessica Gerlich, Tobias Weinmann
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Long-term effectiveness of asthma control medication has been shown in clinical trials but results from observational studies with children and adolescents are lacking. Marginal structural models estimated using targeted maximum l
Externí odkaz:
https://doaj.org/article/f06b8e04390744a89376f13f6ed1fbb6
Akademický článek
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