Zobrazeno 1 - 10
of 449
pro vyhledávání: '"targeted immunotherapy"'
Autor:
Dan Li, Hui Jin, Yan Liu, Jiayin Liu, Xue Zhang, Long Wang, Zhisong Fan, Li Feng, Jing Zuo, Jing Han, Yudong Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveThis study explores the benefits of targeted-immunotherapy combination in third-line or beyond treatment for microsatellite stable (MSS) metastatic colorectal cancer (mCRC) in a real-world setting.MethodsPatients with MSS mCRC who were treat
Externí odkaz:
https://doaj.org/article/96cdba37744c4a77900b327427deea6d
Autor:
Elizabeth Pickup, Christopher Redmond, Matthew A. Sherman, Lakshmi Ramachandran Nair, Sangeeta Sule, Elizabeth Wells, Alexandra B. Kornbluh
Publikováno v:
Annals of the Child Neurology Society, Vol 2, Iss 2, Pp 168-175 (2024)
Abstract Objective Overlap syndromes have been described between N‐methyl‐ d‐aspartate receptor encephalitis (NMDARE) and other neuroinflammatory conditions, although rarely involving neurosarcoidosis. Molecularly targeted immunotherapy may be
Externí odkaz:
https://doaj.org/article/af55391982594ddc83d7300121b77e5f
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Breast cancer (BC) is the second-leading factor of mortality for women globally and is brought on by a variety of genetic and environmental causes. The conventional treatments for this disease have limitations, making it difficult to improve
Externí odkaz:
https://doaj.org/article/016dbfdba0e546e1acf466c6b3b3fe47
Autor:
Yaya Chu, Gaurav Nayyar, Meijuan Tian, Dean A. Lee, Mehmet F. Ozkaynak, Jessica Ayala-Cuesta, Kayleigh Klose, Keira Foley, Alyssa S. Mendelowitz, Wen Luo, Yanling Liao, Janet Ayello, Gregory K. Behbehani, Stanley Riddell, Timothy P. Cripe, Mitchell S. Cairo
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200820- (2024)
The prognosis for children with recurrent and/or refractory neuroblastoma (NB) is dismal. The receptor tyrosine kinase-like orphan receptor 1 (ROR1), which is highly expressed on the surface of NB cells, provides a potential target for novel immunoth
Externí odkaz:
https://doaj.org/article/2644140197174223981934890cc1a2e8
Autor:
Witida Laopajon, Nuchjira Takheaw, Kamonporn Kotemul, Supansa Pata, Suradej Hongeng, Watchara Kasinrerk
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 4, Iss 6, Pp 1145-1156 (2023)
Aim: The present study aims to generate chimeric mouse single-chain variable fragment (scFv) and immunoglobulin G1 (IgG1) crystallizable fragment (Fc) antibody against disialoganglioside (GD2) for the treatment of neuroblastoma (NB). The generated sc
Externí odkaz:
https://doaj.org/article/34d65b7957394f8e82d8ec4a81ca6295
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Gangliosides are glycosphingolipids with prevalence in nervous tissue and their involvement in certain neuronal diseases have been widely known. Interestingly, many recent studies highlighted their importance in the development and progression of var
Externí odkaz:
https://doaj.org/article/026fe6518de94beaa2c36f5f858578ae
Autor:
Bin Wang, Maoping Tang, Ziwei Yuan, Zhongyu Li, Bin Hu, Xin Bai, Jinxian Chu, Xiaoyang Xu, Xue-Qing Zhang
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 232-248 (2022)
Immunotherapy is emerging as a powerful tool for combating many human diseases. However, the application of this life-saving treatment in serious brain diseases, including glioma, is greatly restricted. The major obstacle is the lack of effective tec
Externí odkaz:
https://doaj.org/article/7a41d2d2cab6488eb14ef3ee3939d080
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is one of the most prevalent cancer types and the leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) accounts for 80-85% of all cancer incidences. Lung cancer therapy and prognosis largely depend on the d
Externí odkaz:
https://doaj.org/article/0fc9250adb7042138a90cf2d0751c83a
Autor:
Christopher M Harpur, Alison C West, Mélanie A Le Page, Maggie Lam, Christopher Hodges, Osezua Oseghale, Andrew J Gearing, Michelle D Tate
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 3, Pp n/a-n/a (2023)
Abstract Objectives Novel host‐targeted therapeutics could treat severe influenza A virus (IAV) infections, with reduced risk of drug resistance. LAT8881 is a synthetic form of the naturally occurring C‐terminal fragment of human growth hormone.
Externí odkaz:
https://doaj.org/article/11ff7667bc7c44c4a9ff402e4a1045e1