Zobrazeno 1 - 10
of 186
pro vyhledávání: '"tapinarof"'
Autor:
Hesham Salem, Mahmoud A. Abdelmajed, Hoda Madian, Nadeen Emad, Sara Osama, Amir Ata, Ebtihal Samir
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-9 (2024)
Abstract Topical tapinarof is used to treat plaque psoriasis (a skin disease in which red and scaly patches form are appeared on some areas of the body). The goal of the current research is to establish a facile and rapid fluorimetric technique for t
Externí odkaz:
https://doaj.org/article/d796de2c5a094483816816e31acadae6
Akademický článek
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Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Background: Tapinarof is a nonsteroidal, topical, aryl hydrocarbon receptor agonist. Tapinarof has been shown to be efficacious and have acceptable safety profile in the treatment of atopic dermatitis (AD).Objective: We sought to evaluate the improve
Externí odkaz:
https://doaj.org/article/ca3f5f18158f423495f802d4db1d2eb1
Autor:
Leon Kircik, Matthew Zirwas, Shawn G. Kwatra, G. Michael Lewitt, Holly Glover, Tomas Chao, Philip M. Brown, David S. Rubenstein, Anna M. Tallman
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 1, Pp 201-211 (2023)
Abstract Introduction Patients with psoriasis report pruritus as their most bothersome symptom. Tapinarof cream 1% once daily demonstrated significant efficacy versus vehicle and was well tolerated in adults with mild to severe plaque psoriasis in tw
Externí odkaz:
https://doaj.org/article/2c5d9e4972684e8faa868f89e77d9aad
Autor:
Barbara Balogh, Ágota Pető, Ádám Haimhoffer, Dávid Sinka, Dóra Kósa, Pálma Fehér, Zoltán Ujhelyi, Monica Argenziano, Roberta Cavalli, Ildikó Bácskay
Publikováno v:
Gels, Vol 10, Iss 11, p 675 (2024)
Psoriasis is an immune-mediated skin condition. There are many therapeutic options for its treatment; however, none of them is completely effective. Tapinarof is a promising new active substance; it was recently approved by the FDA for the treatment
Externí odkaz:
https://doaj.org/article/6e0529bc7ace429985dddbff2562f685
Publikováno v:
Psoriasis: Targets and Therapy, Vol Volume 13, Pp 59-69 (2023)
Riley K Spencer,1,2 Joy Q Jin,2,3 Kareem G Elhage,2 Mitchell S Davis,2 Wilson Liao,2 Tina Bhutani2 1Arizona College of Osteopathic Medicine, Midwestern University, Glendale, AZ, USA; 2Department of Dermatology, University of California at San Francis
Externí odkaz:
https://doaj.org/article/8e86a99cfa254f25bfb75a091e8643cc
Autor:
Seemal R. Desai, Linda Stein Gold, Michael C. Cameron, Alexandra Golant, G. Michael Lewitt, Matthew J. Bruno, George Martin, Philip M. Brown, David S. Rubenstein, Victoria Butners, Anna M. Tallman
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 10, Pp 2443-2460 (2023)
Abstract Tapinarof cream 1% (VTAMA®; Dermavant Sciences, Inc.) is a non-steroidal, topical, aryl hydrocarbon receptor agonist approved by the US Food and Drug Administration (FDA) to treat plaque psoriasis in adults and under investigation for the t
Externí odkaz:
https://doaj.org/article/765499add9ea47908d1b15a7a34f1ce3
Akademický článek
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Publikováno v:
JAAD Case Reports, Vol 45, Iss , Pp 66-67 (2024)
Externí odkaz:
https://doaj.org/article/bab3a47ab5f147e189b98f0dffbb0062
Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis
Autor:
Steven P. Proper, Alexander T. Dwyer, Andrews Appiagyei, Jennifer M. Felton, Netali Ben-Baruch Morgenstern, Justin M. Marlman, Michael Kotliar, Artem Barski, Ty D. Troutman, Marc E. Rothenberg, Tesfaye B. Mersha, Nurit P. Azouz
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IntroductionAtopic dermatitis (AD) is an allergic skin disease mediated by skin barrier impairment and IL-13-driven immune response. Activation of the aryl hydrocarbon receptor (AHR) has shown promise in early clinical trials for AD; however, the mec
Externí odkaz:
https://doaj.org/article/250f10865655442983c6157c3f1b2cd5