Zobrazeno 1 - 10
of 132
pro vyhledávání: '"tRNA-derived fragment"'
Autor:
Matthew Uzelac, Weg M. Ongkeko
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102135- (2024)
Roughly 54,000 individuals are diagnosed with head and neck cancers in the United States yearly. Transfer RNA-derived fragments (tRF) are the products of enzymatic cleavage of precursor tRNAs, and have been proposed for use as biomarkers of head and
Externí odkaz:
https://doaj.org/article/fc263f627d4c43868e373cc6c2e77e0b
Autor:
Annie N. Do, Shruti Magesh, Matthew Uzelac, Tianyi Chen, Wei Tse Li, Michael Bouvet, Kevin T. Brumund, Jessica Wang-Rodriguez, Weg M. Ongkeko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10631 (2024)
Transfer-RNA-derived fragments (tRFs) are a novel class of small non-coding RNAs that have been implicated in oncogenesis. tRFs may act as post-transcriptional regulators by recruiting AGO proteins and binding to highly complementary regions of mRNA
Externí odkaz:
https://doaj.org/article/87967fcc2a2f4ae5bf112a67046c615f
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Glioblastoma (GBM) is the most aggressive malignant primary brain tumor. The transfer RNA-derived fragments (tRFs) are a new group of small noncoding RNAs, which are dysregulated in many cancers. Until now, the expression and func
Externí odkaz:
https://doaj.org/article/dd26a97824e04e018dfc84503ea38b81
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Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe transition from a healthy gastric mucosa to gastric cancer is a multi-step process. Early screening can significantly improve the survival rate of gastric cancer patients. A reliable liquid biopsy for gastric cancer prediction is urgent
Externí odkaz:
https://doaj.org/article/813b78f26a30486eba7d01f4d74833cf
Autor:
Qiuyang Chen, Linyuan Shen, Tianci Liao, Yanhao Qiu, Yuhang Lei, Xingyu Wang, Lei Chen, Ye Zhao, Lili Niu, Yan Wang, Shunhua Zhang, Li Zhu, Mailin Gan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14552 (2023)
As a novel non-coding RNA with important functions corresponding to various cellular stresses, the function of tRFs in angiogenesis remains unclear. Firstly, small RNA sequencing was performed on normal and post-muscle injury mouse tibialis anterior
Externí odkaz:
https://doaj.org/article/dca1fba164b14ec588b616a702019876
Akademický článek
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Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: Bladder cancer (BLCA) is one of the most common cancer types worldwide. The disease is responsible for about 200,000 deaths annually, thus improved diagnostics and therapy is needed. A large body of evidence reveal that small RNAs of less
Externí odkaz:
https://doaj.org/article/e62a02d3d1aa4953b009ba417d414862
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 322 (2022)
(1) Transfer RNA (tRNA)-derived fragments (tRFs) are a new category of regulatory non-coding RNAs with distinct biological functions in cancer. They are produced from pre-tRNAs or mature tRNAs and their sequences are relatively short; thus, the ampli
Externí odkaz:
https://doaj.org/article/dcbe4aeeea2a458ea4ee3dea00310be2