Zobrazeno 1 - 10
of 262
pro vyhledávání: '"tRNA modifications"'
Autor:
Matthieu G. Gagnon, Jiqiang Ling
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/5e5ddef3f16d4343b1a52375d0239f5b
Autor:
Yun Li, Zongyu Yu, Wenlin Jiang, Xinyi Lyu, Ailian Guo, Xiaorui Sun, Yiting Yang, Yunfang Zhang
Publikováno v:
Biomolecules, Vol 14, Iss 10, p 1340 (2024)
As the most ancient RNA, transfer RNAs (tRNAs) play a more complex role than their constitutive function as amino acid transporters in the protein synthesis process. The transcription and maturation of tRNA in cells are subject to stringent regulatio
Externí odkaz:
https://doaj.org/article/a024b83832d84db99471beeda2c33ea2
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Methylthiotransferases (MTTases) are radical S-adenosylmethionine (SAM) enzymes that catalyze the addition of a methylthio (-SCH3) group to an unreactive carbon center. These enzymes are responsible for the production of 2-methylthioadenosine (ms2A)
Externí odkaz:
https://doaj.org/article/b586e04207044e328901ce26701610e1
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Viruses completely depend on the host translation machineries to express the viral proteins. Recent data reveal an unprecedented interaction of positive strand RNA ((+)RNA) viruses with the host tRNA epitranscriptome to favor viral protein expression
Externí odkaz:
https://doaj.org/article/a5afac8f895f4bacb7e470567bcdc8d3
Akademický článek
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Autor:
Xiwen Liu, Ruoyu Chen, Yujie Sun, Ran Chen, Jie Zhou, Qingnan Tian, Xuan Tao, Zhang Zhang, Guan-zheng Luo, Wei Xie
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background The adenosine-to-inosine (A-to-I) editing in anticodons of tRNAs is critical for wobble base-pairing during translation. This modification is produced via deamination on A34 and catalyzed by the adenosine deaminase acting on tRNA
Externí odkaz:
https://doaj.org/article/29fcbe9aa0eb47beb79997647b29e3cf
Autor:
Zhihang Chen, Wanjie Zhu, Shenghua Zhu, Kaiyu Sun, Junbin Liao, Haining Liu, Zihao Dai, Hui Han, Xuxin Ren, Qingxia Yang, Siyi Zheng, Baogang Peng, Sui Peng, Ming Kuang, Shuibin Lin
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 12, Pp n/a-n/a (2021)
Abstract Background N7‐methylguanosine (m7G) modification is one of the most common transfer RNA (tRNA) modifications in humans. The precise function and molecular mechanism of m7G tRNA modification in hepatocellular carcinoma (HCC) remain poorly u
Externí odkaz:
https://doaj.org/article/cfe522a8965f4ad4acfb6ece699d17fc
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/f89bd9e3ceb44bd3bec70a185db15c76
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Lung cancer, one of the most malignant tumors, has extremely high morbidity and mortality, posing a serious threat to global health. It is an urgent need to fully understand the pathogenesis of lung cancer and provide new ideas for its treatment. Int
Externí odkaz:
https://doaj.org/article/8c3126d152de4ec29802cc3d7649112a
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background The uneven use of synonymous codons in the transcriptome regulates the efficiency and fidelity of protein translation rates. Yet, the importance of this codon bias in regulating cell state-specific expression programmes is current
Externí odkaz:
https://doaj.org/article/9544b0e83302442294142357427874d7