Zobrazeno 1 - 10
of 94
pro vyhledávání: '"tPA, tissue plasminogen activator"'
Autor:
Liang Han, Chen Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 8, Pp 2306-2325 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and severely limits brain penetration of systemically administered drugs, resulting in ineffective drug therapy of brain diseases. However, during the onset and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a05eff9f72ac70fe48cb5ed9a111b5b
http://www.sciencedirect.com/science/article/pii/S2211383520308522
http://www.sciencedirect.com/science/article/pii/S2211383520308522
Publikováno v:
Medicina; Volume 58; Issue 10; Pages: 1355
Background and Objectives: Thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA) is used to treat acute ischemic stroke. Dabigatran is a reversible thrombin inhibitor approved for stroke prevention in patients with nonvalvul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69070c52573ed612aa4050b19e7ad050
https://pubmed.ncbi.nlm.nih.gov/36295516
https://pubmed.ncbi.nlm.nih.gov/36295516
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 29, Iss 7, Pp 764-774 (2021)
Saudi Pharmaceutical Journal, Vol 29, Iss 7, Pp 764-774 (2021)
Background Arterial catheterization is frequently performed in neonatal intensive care units with an inherent risk of peripheral ischemic injury, especially in preterm infants. The treatment options following vascular damage involve invasive and non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1058cf71ce13334703010fe405bd9a76
http://europepmc.org/articles/PMC8347849
http://europepmc.org/articles/PMC8347849
Autor:
Kurt D. Piggott, Jason Turner, LaTasha Lewis, Song-Gui Yang, Cynthia Laviolette, Timothy W. Pettitt
Publikováno v:
JACC Case Reports
Pulmonary artery thrombosis is reported in neonates with risk factors for hypercoagulability. No consensus exists regarding standard therapy for this condition. We present a neonate, with no risk factors for thrombosis, who was admitted after birth t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7c6de5f932b3e27e0baa163a161a07
http://europepmc.org/articles/PMC8353554
http://europepmc.org/articles/PMC8353554
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 5, Pp 1341-1354 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Breast cancer brain metastases (BCBMs) are one of the most difficult malignancies to treat due to the intracranial location and multifocal growth. Chemotherapy and molecular targeted therapy are extremely ineffective for BCBMs due to the inept brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8871da41ea9c8b40f305cc15fb1a6f
https://doi.org/10.1016/j.apsb.2020.10.015
https://doi.org/10.1016/j.apsb.2020.10.015
Publikováno v:
Thrombosis Research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3e4c5bb130680eabc67062f6391a0f
http://europepmc.org/articles/PMC8686202
http://europepmc.org/articles/PMC8686202
Autor:
Xueyuan Yang, Soo K. Shin, Jin Xie, Kylee J. Duberstein, Madison M. Fagan, Simon R. Platt, Kelly M. Scheulin, Erin E. Kaiser, Holly A. Kinder, Elizabeth S. Waters, Julie Jeon, Franklin D. West, Anil Kumar, Hea Jin Park
Publikováno v:
IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
Background The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f797c86f00c6b2f76590c2d6fd382a6
http://europepmc.org/articles/PMC8019951
http://europepmc.org/articles/PMC8019951
Autor:
Deborah Pushparajah, Salma Jimenez, Shirley Wong, Hibah Alattas, Roderick A. Slavcev, Nafiseh Nafissi
Publikováno v:
Advanced Drug Delivery Reviews
The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan City, China in December 2019. Scientific communities around the world hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94880f08a67e236cd51c7dda2e6ac22e
http://europepmc.org/articles/PMC7789827
http://europepmc.org/articles/PMC7789827
Autor:
Djedjiga Abdelhamid, Massoud Mirshahi, Shahsoltan Mirshahi, Iman Al dybiat, Meriem Belalou, Marc Pocard, Matti Ullah, Jeannette Soria, Shahid Shah
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 809-819 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Aim Evaluation of fibrin role on cancer cells implantation in injured tissues and studying the molecular mechanism of cancer cell interaction with the peritoneal damage. Material and methods Mouse colon cancer (CT26) and human mesothelial cells (HMCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6baa12bc8e7c11ff2fbb3e3377a366
http://www.sciencedirect.com/science/article/pii/S1476558620301524
http://www.sciencedirect.com/science/article/pii/S1476558620301524
Autor:
Ishtiaque Ahammad, Samia Sultana Lira
Publikováno v:
International Journal of Biological Macromolecules
SARS-CoV-2 is the deadly virus behind COVID-19, the disease that went on to ravage the world and caused the biggest pandemic 21st century has witnessed so far. On the face of ongoing death and destruction, the urgent need for the discovery of a vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352a07660711c1227db925386eb3a8b5
https://doi.org/10.1016/j.ijbiomac.2020.06.213
https://doi.org/10.1016/j.ijbiomac.2020.06.213