Zobrazeno 1 - 10
of 138
pro vyhledávání: '"tDNA"'
Autor:
Patrizio Giacomini, Fabio Valenti, Matteo Allegretti, Matteo Pallocca, Francesca De Nicola, Ludovica Ciuffreda, Maurizio Fanciulli, Stefano Scalera, Simonetta Buglioni, Elisa Melucci, Beatrice Casini, Mariantonia Carosi, Edoardo Pescarmona, Elena Giordani, Francesca Sperati, Nicoletta Jannitti, Martina Betti, Marcello Maugeri-Saccà, Fabiana Letizia Cecere, Veronica Villani, Andrea Pace, Marialuisa Appetecchia, Patrizia Vici, Antonella Savarese, Eriseld Krasniqi, Virginia Ferraresi, Michelangelo Russillo, Alessandra Fabi, Lorenza Landi, Gabriele Minuti, Federico Cappuzzo, Massimo Zeuli, Gennaro Ciliberto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Molecular Tumor Boards (MTB) operating in real-world have generated limited consensus on good practices for accrual, actionable alteration mapping, and outcome metrics. These topics are addressed herein in 124 MTB patients, all re
Externí odkaz:
https://doaj.org/article/8cd52fa220ea4469af2300403ba19259
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Malignant primary brain tumors are the most common cancer in children aged 0–14 years, and are the most common cause of death among pediatric cancer patients. Compared to other cancers, pediatric brain tumors have been difficult to diagnose and stu
Externí odkaz:
https://doaj.org/article/36f0af5885ae421299e5c95652a593b3
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Gliomas are tumors derived from mutations in glial brain cells. Gliomas cause significant morbidity and mortality and development of precision diagnostics and novel targeted immunotherapies are critically important. Radiographic imaging is the most c
Externí odkaz:
https://doaj.org/article/47e3e13cdbda4542af7565028d7866e6
Akademický článek
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Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background The human genome is hierarchically organized into local and long-range structures that help shape cell-type-specific transcription patterns. Transfer RNA (tRNA) genes (tDNAs), which are transcribed by RNA polymerase III (RNAPIII)
Externí odkaz:
https://doaj.org/article/a0d62565df354eec80d90fab7141c26f
Autor:
Emil Aalto-Setälä, Georgiy A. Belogurov, Jacob Bakermans, David L.V. Bauer, Anssi M. Malinen, Olena Parilova, David Dulin, Martin Blessing, Achillefs N. Kapanidis
Publikováno v:
Journal of Molecular Biology
Malinen, A M, Bakermans, J, Aalto-Setälä, E, Blessing, M, Bauer, D L V, Parilova, O, Belogurov, G A, Dulin, D & Kapanidis, A N 2022, ' Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway ', Journal of Molecular Biology, vol. 434, no. 2, 167383, pp. 1-18 . https://doi.org/10.1016/j.jmb.2021.167383
Journal of Molecular Biology, 434(2):167383, 1-18. Academic Press Inc.
Malinen, A M, Bakermans, J, Aalto-Setälä, E, Blessing, M, Bauer, D L V, Parilova, O, Belogurov, G A, Dulin, D & Kapanidis, A N 2022, ' Real-Time Single-Molecule Studies of RNA Polymerase–Promoter Open Complex Formation Reveal Substantial Heterogeneity Along the Promoter-Opening Pathway ', Journal of Molecular Biology, vol. 434, no. 2, 167383, pp. 1-18 . https://doi.org/10.1016/j.jmb.2021.167383
Journal of Molecular Biology, 434(2):167383, 1-18. Academic Press Inc.
Graphical abstract
Highlights • The formation of single RNA polymerase–promoter open complexes probed in real-time. • Substantial heterogeneity was found along the promoter-opening pathway. • Branched steps include template strand loadin
Highlights • The formation of single RNA polymerase–promoter open complexes probed in real-time. • Substantial heterogeneity was found along the promoter-opening pathway. • Branched steps include template strand loadin
Autor:
Wang, Yuxuan, Springer, Simeon, Zhang, Ming, McMahon, K. Wyatt, Kinde, Isaac, Dobbyn, Lisa, Ptak, Janine, Brem, Henry, Chaichana, Kaisorn, Gallia, Gary L., Gokaslan, Ziya L., Groves, Mari L., Jallo, George I., Lim, Michael, Olivi, Alessandro, Quinones-Hinojosa, Alfredo, Rigamonti, Daniele, Riggins, Greg J., Sciubba, Daniel M., Weingart, Jon D., Wolinsky, Jean-Paul, Ye, Xiaobu, Oba-Shinjo, Sueli Mieko, Marie, Suely K. N., Holdhoff, Matthias, Agrawal, Nishant, Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Bettegowda, Chetan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Aug 01. 112(31), 9704-9709.
Externí odkaz:
https://www.jstor.org/stable/26464287
Akademický článek
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Autor:
Ana Catarina S Lopes, Juliana Falcão Rodrigues, Maysa BM Clementino, Catia AC Miranda, Ana Paula A Nascimento, Marcos Antônio de Morais Júnior
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 102, Iss 7, Pp 827-832 (2007)
PCR analysis of 16S-23S internal transcribed spacer (PCR ribotyping) and tRNA intergenic spacer (tDNA-PCR) were evaluated for their effectiveness in identification of clinical strains of Klebsiella pneumoniae and differentiation with related species.
Externí odkaz:
https://doaj.org/article/c583d279f0014b95aa5c2a145646b192