Zobrazeno 1 - 10
of 2 260
pro vyhledávání: '"t-all"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 12297-12309 (2024)
Xiangbo Zeng,1,2,* Dingrui Nie,1,3,* Zhen Liu,2 Xueting Peng,1 Xianfeng Wang,1 Kangjie Qiu,1 Shuxin Zhong,1 Ziwei Liao,4 Xianfeng Zha,1,5 Yangqiu Li,1,2 Chengwu Zeng1 1Key Laboratory for Regenerative Medicine of Ministry of Education, Institu
Externí odkaz:
https://doaj.org/article/cac9b44f350c4d5faefb9891e09f723f
Publikováno v:
The Application of Clinical Genetics, Vol Volume 17, Pp 187-198 (2024)
Agata Rocka,1 Maria Suchcicka,2 Aleksandra M Jankowska,2 Magdalena M Woźniak,1 Monika Lejman3 1Pediatric Radiology, Medical University of Lublin, Medical University of Lublin, Prof. Antoni Gębali 6, Lublin, 20-093, Poland; 2Student Scien
Externí odkaz:
https://doaj.org/article/6e8d374939664af987b8ac58545d20c6
Autor:
Tongting Ji, Yang Yang, Juanjuan Yu, Hongli Yin, Xinran Chu, Pengju Yang, Ling Xu, Xiaodong Wang, Shaoyan Hu, Yizhen Li, Xiaochen Wu, Wengyuan Liu, Bi Zhou, Wenjuan Wang, Shuqi Zhang, Wei Cheng, Yanling Chen, Lei Shi, Zhiheng Li, Ran Zhuo, Yongping Zhang, Yanfang Tao, Di Wu, Xiaolu Li, Zimu Zhang, Jun-jie Fan, Jian Pan, Jun Lu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Despite the use of targeted therapeutic approaches, T-cell acute lymphoblastic leukemia (T-ALL) is still associated with a high incidence of complications and a poor prognosis. Indisulam (also known as E7070), a newly identified m
Externí odkaz:
https://doaj.org/article/fe8dbc62f5da40a89726b93bc9a83c7e
Autor:
H. Daniel Lacorazza
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The MAP2K7 signaling pathway activates the c-Jun NH2-terminal protein kinase (JNK) in response to stress signals, such as inflammatory cytokines, osmotic stress, or genomic damage. While there has been interest in inhibiting JNK due to its involvemen
Externí odkaz:
https://doaj.org/article/ff6e42e5dfdd4a3da9bf27b3171caab3
Autor:
Punit Jain, Poonam Jain, Robert S. Ohgami, Veena Pawar, Kunal Sehgal, Pradnya Chaudhari, Ravindra Nikalji, Tejinder Singh, Vipin Khandelwal, Sanjay Khare, Vaishali Lokhande, Ashwathy Haridas, Laxman Jessani, Kanika Khandelwal
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 251-255 (2024)
Abstract Primary renal involvement by T lymphoblasts is rare among adults with T acute lymphoblastic leukaemia. We report a 28‐year‐old man presenting with acute renal failure due to infiltration by T lymphoblasts and his response to paediatric
Externí odkaz:
https://doaj.org/article/fb2a4533e9ab4efba1a634ed819ed01c
Publikováno v:
Research Results in Pharmacology, Vol 10, Iss 2, Pp 27-39 (2024)
Introduction: Acute lymphoblastic leukemia (ALL) is the most frequent pediatric leukemia; it can be defined according to chromosomic and genomic data. Cytogenetic analyses and determination of chromosomal numbers (such as hypo- or hyperdiploidy) and/
Externí odkaz:
https://doaj.org/article/e06b932a662b4d8eaa73c281f1f65503
Autor:
Libuse Lizcova, Eva Prihodova, Lenka Pavlistova, Karla Svobodova, Ester Mejstrikova, Ondrej Hrusak, Pavla Luknarova, Iveta Janotova, Lucie Sramkova, Jan Stary, Zuzana Zemanova
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background T-cell acute lymphoblastic leukemia (T-ALL) represents a rare and clinically and genetically heterogeneous disease that constitutes 10–15% of newly diagnosed pediatric ALL cases. Despite improved outcomes of these children, the
Externí odkaz:
https://doaj.org/article/dd9bf69a7ebc4b1da84c61d75b2dbb82
Autor:
Zhixiong Zhu, Hexian Li, Qizhong Lu, Zongliang Zhang, Jia Li, Zeng Wang, Nian Yang, Zhengyu Yu, Chen Yang, Yongdong Chen, Huaqing Lu, Wei Wang, Ting Niu, Chunlai Nie, Aiping Tong
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Clinical trials of Chimeric Antigen Receptor T‐cell (CAR‐T) therapy have demonstrated remarkable success in treating both solid tumors and hematological malignancies. Nanobodies (Nbs) have emerged as promising antigen‐targeting domains
Externí odkaz:
https://doaj.org/article/8b15ce605dcc484b9a66e75fbf9aa14f
Publikováno v:
eLife, Vol 12 (2024)
In T-cell acute lymphoblastic leukemia (T-ALL), more than 50% of cases display autoactivation of Notch1 signaling, leading to oncogenic transformation. We have previously identified a specific chemovar of Cannabis that induces apoptosis by preventing
Externí odkaz:
https://doaj.org/article/992a7a0a20fe47ebbdecbe6108e0dd96
Autor:
Jiajie Jing, Yuan Ma, Ziwen Xie, Bingyan Wang, Yueming Chen, Enjie Chi, Jiadong Wang, Kejin Zhang, Zhujun Wang, Sisi Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute lymphoblastic leukemia (ALL) is a prevalent malignancy affecting the hematopoietic system, encompassing both B-cell ALL (B-ALL) and T-cell ALL (T-ALL). T-ALL, characterized by the proliferation of T-cell progenitors in the bone marrow, presents
Externí odkaz:
https://doaj.org/article/00585f0c291c4af8b9a193fafc1491ee